Exploring the antimicrobial and antioxidative potential of Leucas aspera (Willd.) link: Phytochemical screening, molecular docking, and HR-LC/MS profiling against SARS-CoV-2 protei... by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…Molecular docking of the 19 compounds against the SARS-CoV-2 main protease (3CLPro) protein (PDB ID: 6LU7) and spike protein receptor binding domain (SGp-RBD) protein (PDB ID: 2GHV) revealed Famprofazone and Loxtidine compounds having the highest binding affinity with LibDock scores of 105.53 and 116.70 respectively. …”
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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Finally, we discovered that all biomarkers could bind to MLT with a strong binding energy. Conclusion: Our study identified three novel biomarkers related to MLT for AD, namely, GPRC5B, NFKBIA and RASSF4, providing a novel approach for the investigation and treatment of AD patients.…”
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Esophagoplasty Using a Jejunum Segment on a Vascular Pedicle by D. V. Ruchkin, V. A. Kozlov, M. M. Khamidov, D. E. Okonskaya, N. B. Kovalerova

“…Relaparotomy was required in one patient on day 7 after surgery for bile peritonitis, the cause of which was destructive acalculous cholecystitis with perforation. …”
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Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless. by Weronika Fic, François Juge, Johann Soret, Jamal Tazi

“…The genetic programs specifying eye development are highly conserved during evolution and involve the vertebrate Pax-6 gene and its Drosophila melanogaster homolog eyeless (ey). …”
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Freedom of Expression in South Sudanese Judicial Struggle: Bought or Fought For? With Special Reference to India by Varun Chhachhar, Wol Deng Akech

“…The paper seeks to reckon the concerned institutions in South Sudan to the ongoing liberal jurisprudences on the right to freedom of speech and expression on one hand and on the other hand informs the concerned institutions for a serious litigation and enforcement of Bill of Rights in South Sudan. Indeed, the paper has invoked progressive interpretations of fundamental rights from the U.K, India, and the U.S to help in justifying the grounds as to why South Sudanese litigants and courts should scarcely claim and upheld freedom of expression as fundamental and foundational tenet of a democratic society. …”
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Gastroesophageal reflux disease, resistant to proton pump inhibitors by V. O. Kaybysheva, A. S. Trukhmanov, V. T. Ivashkin

“…Potentials of treatment of the patients with sustained symptoms of GERD on a background of standard dose of proton pump inhibitors (PPI), include correction drug intake, doubling of PPI dose, application of intravenous forms, combination of antisecretory agents of different groups, addition to therapy of drugs, capable to adsorb bile components and modulation of psychoemotional status of patients.Conclusion. …”
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Sex and gender differences in the molecular etiology of Parkinson’s disease: considerations for study design and data analysis by Samantha L. Schaffner, Kira N. Tosefsky, Amy M. Inskter, Silke Appel-Cresswell, Julia M. Schulze-Hentrich

“…While the neuroprotective properties of estrogen are strongly implicated in reduced prevalence of PD in women, interactions with genotype and gender-biased lifestyle factors are incompletely understood. …”
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Noninvasive markers of inflammatory bowel disease activity by A. V. Nikitin, L. V. Vasilyeva, Anatoly A. Matiukhin

“…Fecal calprotectin and TNF-α levels were much higher in patients with high disease activity and extent of inflammatory process. …”
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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I by Bryan Neumann, Stephen McCarthy, Shane Gonen

“…We find that Protoxin-I binds to and displaces the VSDII S3-S4 linker, hindering translocation of the S4II helix during activation.…”
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Die oudheid van die letter en die nuutheid van die Gees. Enkele opmerkings oor die Skrif as lewende Woord by P. F. Theron

“…The contrast between gramma and pneuma, old and new, permeates the entire Bible (i.e. Old and New Testament). This tension is the work of the Spirit as the auctor primarius of Scripture, through which the “dead letter” is transformed into the living Word. …”
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An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants by Bruce Nmezi, Guillermo Rodriguez Bey, Talia DeFrancesco Oranburg, Kseniia Dudnyk, Santana M. Lardo, Nathan Herdman, Anastasia Jacko, Sandy Rubio, Emanuel Loeza-Alcocer, Julia Kofler, Dongkyeong Kim, Julia Rankin, Emma Kivuva, Nicholas Gutowski, Katherine Schon, Jelle van den Ameele, Patrick F. Chinnery, Sérgio B. Sousa, Filipe Palavra, Camilo Toro, Filippo Pinto e Vairo, Jonas Saute, Lisa Pan, Murad Alturkustani, Robert Hammond, Francois Gros-Louis, Michael S. Gold, Yungki Park, Geneviève Bernard, Raili Raininko, Jian Zhou, Sarah J. Hainer, Quasar S. Padiath

“…This element consists of CTCF binding sites that mediate three-dimensional chromatin looping involving LMNB1 and the recruitment of the PRC2 transcriptional repressor complex. …”
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Recirculation of digestive enzymes by G. F. Korot'ko

“…The principle of enterohepatic circulation of bile acids in general view is repeated at interorgan recirculation of hydrolases of the digestive glands providing process of digestion, and by enzyme signaling – integration and adaptation of functions of the gut organs by modulating effects.…”
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Wkład Tomasza Cranmera w rozwój angielskiej reformacji by Wojciech Medwid

“…As a part of his reform program he worked on the revision of canon law, a correction formula of the prayer book and formation of doctrine, which were ingrained in the Bible and the patristic thought. He argued about spiritual presence of Christ in the Eucharist. …”
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Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling by Ying Cheng, Man Zhang, Chenguang Li, Long Su, Lingli Fu, Shi Wu, Chaofei Xu, Bei Sun, Liming Chen

“…AGGF1 upregulates the expression of cell cycle proteins by increasing the binding of tumour necrosis factor ligand superfamily member 12 (TNFSF12) to fibroblast -growth -factor-inducible 14 (FN14, TNFRSF12A). …”
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Effects of benzotriazoles UV-328, UV-329, and UV-P on the self-renewal and adipo-osteogenic differentiation of human mesenchymal stem cells by Yue Zhang, Hui Zhao, Qianxi Feng, Rui Guo, Li Zhong, Shengxian Liang

“…Dual-luciferase reporter assays confirmed UV-P's interaction with PPARγ_LBD at an alternate binding site outside the canonical pocket. These findings raise concerns about the health impacts of BUVSs, particularly UV-P, and underscore the need for further investigation into their toxicological profiles.…”
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Design of a Rain Water Harvesting System at Faculty of Engineering, Technology, Applied Art and Design, Kabale University. by Nyanzi Ibrahim

“…This project aimed at designing a Rain water harvesting system at Kabale Univeristy,Faculty of Engineering as the solution to overcome the problem of the intermittent water supply from the main water supply by National water and sewerage corporation in addition to high water bills at the Faculty. The methods used in this project include Reconnaissance surveying (site attending) aimed at determining rainwater harvesting components available within the area of study eg.roof material and capturing the water demand at the faculty ,Data collection and analysis ie rainfall data captured from kabale district Meteological department.and finally designing the rainwater harvesting system after having all the necessary data at hand. …”
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Design of a Rain Water Harvesting System at Faculty of Engineering, Technology, Applied Art and Design, Kabale University. by Nyanzi, Ibrahim

“…This project aimed at designing a Rain water harvesting system at Kabale Univeristy,Faculty of Engineering as the solution to overcome the problem of the intermittent water supply from the main water supply by National water and sewerage corporation in addition to high water bills at the Faculty. The methods used in this project include Reconnaissance surveying (site attending) aimed at determining rainwater harvesting components available within the area of study eg.roof material and capturing the water demand at the faculty ,Data collection and analysis ie rainfall data captured from kabale district Meteological department.and finally designing the rainwater harvesting system after having all the necessary data at hand. …”
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Design of a Rain Water Harvesting System at Faculty of Engineering, Technology, Applied Art and Design, Kabale University. by Nyanzi, Ibrahim

“…Rain water harvesting is a technology used to collect,convey and storing rain water for later use from relatively clean surface such as roofs,the land surface or rock catchments.This project aimed at designing a Rain water harvesting system at Kabale Univeristy,Faculty of Engineering as the solution to overcome the problem of the intermittent water supply from the main water supply by National water and sewerage corporation in addition to high water bills at the Faculty. The methods used in this project include Reconnaissance surveying (site attending) aimed at determining rainwater harvesting components available within the area of study eg.roof material and capturing the water demand at the faculty ,Data collection and analysis ie rainfall data captured from kabale district Meteological department.and finally designing the rainwater harvesting system after having all the necessary data at hand. …”
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The Pastoral Model of Educating Seniors at Universities of the Third Age at UPJPII in Krakow by Jan Dziedzic

“…The university has a religious profile and implements a pastoral and educational program, that includes lectures and workshops in the field of the Bible and anthropology, ethics, theology, philosophy and history of the Church, as well as an educational and cultural program (religious tourism, theatre arts), that is meant as a form of creative support for seniors. …”
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United Nations and Gender Equality in Nigeria: A Reference of 2010-2020 by IJE O. JAIRUS, AJIYA SARAH, KARUEJE UCHE CHRISTOPER

“…It finally recommends that women status can only be enhanced and can contribute meaningfully to the socio economic and political development of our society if all forms of gender biases are removed and women are not regarded as inferior beings but as people created with equal endowment by God. …”
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