A call for broadening the altmetrics tent to democratize science outreach. by Ivan Jarić, Pavel Pipek, Ana Novoa

“…Common altmetrics indices are limited and biased in the social media that they cover. In this Perspective, we highlight how and why altmetrics should broaden its scope to provide more reliable metrics for scientific content and communication.…”
Get full text

Generosity and Solidarity -A Biblical Contribution and Perspective in Response to Poverty in Africa. by Rugyendo, Medard

“…Poverty has always existed but the Holy Bible isn’t silent about it speaks about the poor and needy but at the same time commands the faithful to give generously to those that are less fortunate in society (( Deut. 24:17-22, 2 Cor. 8 & 9). …”
Get full text

Inequalities within Uniting Reformed Church in Southern Africa on gender, with special reference to lGBTQIA+: Imago Dei by L. Modise

“…The challenge seems to be about the fundamental reading of the Bible, confession, and Church Order articles, which are discussed here. …”
Get full text

Okushoboorora Amatembezo Agu Orikurabamu Kuhinga Oburo Kuruga Aha Kububanjurira Ekishaka Kuhika Aha Kuburya. by Amutuhaire, Elias

“…Ebi mpandiikire omu kucondooza oku nibyoreka bimwe aha matembezo agu orikurabamu kuhinga oburo kuruga aha kububanjurira ekishaka kuhika aha kuburya omuri Nyansoro, Kicuzi, Ibanda. …”
Get full text

Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X by Melanie P. Muller, Alex Mortenson, Josepha C. Sedzro, Po-Chao Wen, James H. Morrissey, Emad Tajkhorshid

“…The TF exosite makes substantial contacts with both the FX- and FVIIa-GLA domains, in which TF residue K165 engages directly with the FVIIa-GLA domain, whereas K166 plays a central role in binding to the FX-GLA domain. These findings underscore the substrate-binding exosite of TF as being pivotal in the formation of the EC, serving as a critical interface linking the GLA domains of both FVIIa and FX.…”
Get full text

The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis. by Qiuling Li, Kayla Y Lim, Raad Altawell, Faith Verderose, Xiling Li, Wanying Dong, Joshua Martinez, Dion Dickman, Nicholas Stavropoulos

“…Here we implicate Insomniac (Inc), a conserved protein required for normal sleep and synaptic homeostasis in Drosophila, as a Cul3 adaptor. Inc binds Cul3 in vivo, and mutations within the N-terminal BTB domain of Inc that weaken Inc-Cul3 associations impair Inc activity, suggesting that Inc function requires binding to the Cul3 complex. …”
Get full text

Medio ambiente y derecho penal by Marco Antonio Terragni

“… El artículo refiere a algunos aspectos de los bienes jurídicos protegidos por esta rama del Derecho Penal y a las carencias que presenta por razón de dificultades metodológicas que parecen insalvables. …”
Get full text

CHURU-KOHO POTTERY OF LAM DONG PROVINCE IN RELATION TO CHAM POTTERY by Van Mon Truong

“…Research shows that Churu-Koho pottery (Lam Dong Province) is related to Cham pottery in Bau Truc (Ninh Thuan Province) and Binh Duc (Binh Thuan Province) and to the pottery of the Sa Huynh culture (Quang Ngai Province), which dates back to 3,000 BP. …”
Get full text

Saving Money at the Grocery Store by Glenda L. Warren

“…Warren, lists 21 strategies to save money on one’s grocery bill. Published by the UF Department of Family Youth and Community Sciences, December 2008. …”
Get full text

Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis by Rahil Ummar Faruk Abbu, Shaik Mohammad Abdul Fayaz, Divyashree M S, Raghu Chandrashekhar H, Prasanna Kumar Reddy Gayam, Archana Mahadev Rao

“…Methods: We examined the binding relationships between telomerase and the phytochemicals by performing molecular docking using Glide – Schrödinger, CB-Dock2 (Covalent Blind Docking 2), and Achilles Blind Docking. …”
Get full text

Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…In this study, we hypothesized that the G-quadruplex (G4)-binding ligands can be used as novel antibiotics as their binding can possibly downregulate/block the expression of vital genes. …”
Get full text

Targeting aldose reductase using natural African compounds as promising agents for managing diabetic complications by Miriam E. L. Gakpey, Shadrack A. Aidoo, Toheeb A. Jumah, George Hanson, Siyabonga Msipa, Florence N. Mbaoji, Omonijo Bukola, Palesa C. Tjale, Mamadou Sangare, Hedia Tebourbi, Olaitan I. Awe

“…The top 20 compounds with the highest binding affinity were selected. Subsequently, in silico analyses such as protein-ligand interaction, physicochemical and pharmacokinetic profiling (ADMET), and molecular dynamics simulation coupled with binding free energy calculations were performed to identify lead compounds with high binding affinity and low toxicity.ResultsFive natural compounds, namely, (+)-pipoxide, Zinc000095485961, Naamidine A, (−)-pipoxide, and 1,6-di-o-p-hydroxybenzoyl-beta-d-glucopyranoside, were identified as potential inhibitors of aldose reductase. …”
Get full text

Self-other distinction modulates the sense of self-agency during joint actions by Laura Zapparoli, Marika Mariano, Lucia Maria Sacheli, Tommaso Berni, Caterina Negrone, Carlo Toneatto, Eraldo Paulesu

“…Implicit sense of agency: in the Coordination task, we found a significant intentional binding effect only in Solo trials but not in Joint ones. …”
Get full text

Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

“…Furthermore, molecular docking and simulation studies showed a binding affinity with negative binding energy with TNF-α (7jra, − 11.342 kcal/mol), TGF-β1 (3tzm, − 9.162 kcal/mol) and NF-κB (1svc, − 6.665 kcal/mol). …”
Get full text

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…We then focus on SARS-CoV-2 infection and show how the binding of the viral pathogen to the angiotensin-converting enzyme 2 receptor, as well as to NRP-1, leads to elevated levels of VEGF-A and consequences such as coagulation, vascular dysfunction, and inflammation. …”
Get full text

Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

“…Results A series of vesamicol derivatives was synthesized and their binding towards VAChT, σ1 and σ2 receptors assessed. …”
Get full text

Clinical and Pathogenetic Parallels of Nonalcoholic Fatty Liver Disease and Gallstone Disease by Aleksey O. Bueverov

“…These include central and peripheral insulin resistance, changes in the expression of transcription factors (liver X-receptor and farnesoid X-receptor) and the bile acid membrane receptors (TGR5). Conversely, the effect of GD on the NAFLD course is assumed, although the pathogenetic factors of this association are still unknown. …”
Get full text

“Sacherklärungen” in biblischen texten - vorkommen und bedeutung für die Bibelübersetzung by C. Stenschke

“…These explanatory notes carry several implications for present day Bible translation and the content of modern Bible editions. …”
Get full text

Reading the New Testament from a theological perspective by H. C. van Zyl

“… This article argues that, from the perspective of the faith community, it is not enough to read the Bible only from a “technical” point of view; a theological perspective is also required. …”
Get full text

Henri Nouwen by RA Jonas

“… Henri Nouwen het gedurende sy leeftyd heelwat invloed uitgeoefen en boeke geskryf binne die veld van spiritualiteit. Sy dood in September 1996 was 'n gevoelige slag vir diegene wat hom persoonlike geken of deur sy boeke met hom kennis gemaak het. …”
Get full text