Screening Criteria for Multiple Organ Dysfunction after Abdominal Surgery (Clinical Research) by S. A. Tachyla, A. V. Marochkov, V. A. Livinskaya

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The effectiveness of complex treatment of endothelial dysfunction in patients with primary open angle glaucoma by A. M. Dusmukhamedova, D. M. Tuychibaeva, A. A. Khadzhimetov

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Influence of diastolic dysfunction on cognitive impairment and prognosis in patients with coronary artery disease by O. O. Nudchenko, L. I. Konoplianyk, N. A. Kozhukharova, M. M. Dolzhenko

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Is there a role for oxidative stress and mitochondrial dysfunction in age-associated bladder disorders? by Lori A Birder

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Reactive Airways Dysfunction Syndrome from Acute Inhalation of Dishwasher Detergent Powder by Timo J Hannu, Vesa E Riihimäki, Päivi L Piirilä

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Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>) by Vladimir A. Marchenko, Irina N. Zhilinskaya

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High-Pressure Pneumoperitoneum Aggravates Surgery-Induced Neuroinflammation and Cognitive Dysfunction in Aged Mice by Bo Lu, Hui Yuan, Xiaojie Zhai, Xiaoyu Li, Jinling Qin, Junping Chen, Bo Meng

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A PBPK modeling approach for personalized dose optimization of nicardipine in renal and hepatic dysfunction by Ammara Ayub, Ammara Zamir, Muhammad Fawad Rasool, Usman Arshad, Faleh Alqahtani

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The Effects of Hyperlipidemia on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Gynecological Tumor Surgery by Shen H, Xiong Y, Liang Y, Liu Z, Guo L, Qin Y, He J, Lin F

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Small RNA-big impact: exosomal miRNAs in mitochondrial dysfunction in various diseases by Xiaqing Li, Yi Han, Yu Meng, Lianghong Yin

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Understanding immune system dysfunction and its context in mood disorders: psychoneuroimmunoendocrinology and clinical interventions by Miguel A. Ortega, Oscar Fraile-Martinez, Cielo García-Montero, Raul Diaz-Pedrero, Laura Lopez-Gonzalez, Jorge Monserrat, Silvestra Barrena-Blázquez, Miguel Angel Alvarez-Mon, Guillermo Lahera, Melchor Alvarez-Mon

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The Effect of Liv.52 DS in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): A Pilot, Randomized, Double-Blind, Placebo-Controlled, Clinical Study by Jalihal U, Nanda RA, Katariya K, Ramanathan B, Kumawat R

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2BALANCE: a cognitive-motor dual-task protocol for individuals with vestibular dysfunction by Maya Danneels, Ruth Van Hecke, Laura Leyssens, Sofie Degeest, Dirk Cambier, Raymond van de Berg, Vincent Van Rompaey, Leen Maes

“…Ultimately, this project could enable individualised and holistic clinical care in these patients, taking into account single as well as dual-task performance.Ethics and dissemination The current study was approved by the ethics committee of Ghent University Hospital on 5 July 2019 with registration number B670201940465. …”
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Risk Factors for Postoperative Neurologic Dysfunction in Patients with Spinal Tuberculosis: A Retrospective Study by Shao P, Wang Y, Dong M, Fan H, Gao Y, Gao Y, Hao Z, Lv J, Bai J, Wu Z, Feng Y

“…We also compared the patients’ pre- and postoperative changes in relevant inflammatory indicators, such as the ESR and PCT.Results: Postoperatively, one patient developed paraplegia with an ASIA grade of A; 29 patients developed incomplete paraplegia with an ASIA score of grade B in 5 patients, grade C in 7 patients, and grade D in 17 patients. …”
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Functional State of Respiratory Muscles in Patients with Chronic Obstructive Pulmonary Disease by I. G. Kurpаtov, B. I. Geltser, V. N. Kotelnikov, M. F. Kinyaykin

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The Clock Drawing Task reveals executive dysfunction in the dialysis population – an underrecognized and underestimated problem by Piotr Olejnik, Aleksandra Golenia, Oliwia Maciejewska, Ewa Wojtaszek, Paweł Żebrowski, Jolanta Małyszko

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The role of endosarcomeric cytoskeleton proteins in the mechanisms of left ventricular diastolic dysfunction: focus on titin by V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, G. E. Chernogoryuk, N. N. Terentyeva, E. V. Grakova, K. V. Kopeva, V. Yu. Usov, N. P. Garganeeva, I. K. Livshits, I. V. Petrova, T. V. Lasukova

“…Impairment of myocardial relaxation and deterioration of its wall compliance under a wide range of pathological conditions (pressure overload, ischemia, inflammation, cardiotoxic effects, oxidative stress, etc.) underlying DD can be explained by a shift in titin expression toward its more rigid N2B isoform, hypophosphorylation by protein kinases A and G or dephosphorylation by serine / threonine phosphatase 5 of its molecule in the extensible protein segment containing a unique N2B sequence, hyperphosphorylation of PEVK regions of titin by protein kinase C, as well as inhibition of the Ca2+-dependent titin – actin interaction.The results of deciphering these mechanisms can become a tool for developing new approaches to targeted therapy for diastolic heart failure that currently does not have effective treatment, on the one hand, and the key to understanding the therapeutic effects of drugs already used to treat chronic heart failure with preserved LV ejection fraction, on the other hand.…”
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Curcumin Analog J7 Attenuates Liver Fibrosis and Metabolic Dysregulation in a Rat Model of Type 2 Diabetes via Modulation of TGF-&beta;/Smad and NF-&kappa;B/BCL-2/BAX Pathways by Ma J, Chen W, Vaishnani DK, Wang C, Xue S, Yang Q, Tong Y, Lei N, Zhao Z, Ying F

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IL-4 and IL-13 in Cardiovascular Disease: From Immune Modulation to Therapeutic Possibilities &amp;ndash; A Narrative Review by Kılıç AT, Bora R, Toprak B

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Effect of exogenous free Nε-(carboxymethyl)lysine on diabetes-associated cognitive dysfunction: neuroinflammation, and metabolic disorders by Huang Zhang, Lan Mo, Xi Chen, Mei Li, Maiquan Li, Yang Xu, Maomao Zeng, Zhiyong He, Qingwu Shen, Jie Chen, Wei Quan

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