Effect of endothelial responses on sepsis-associated organ dysfunction by Miao Wu, Yan Yan, Xinyu Xie, Jiawei Bai, Chengtai Ma, Xianjin Du, Sihan Zhou, Xiuyuan Hao

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Elucidating molecular pathogenesis and developing targeted therapeutic interventions for cerebrovascular endothelial cell-mediated vascular dementia by Yanrong Yang, Hua Chen, Qibing Liu, Yang Niu, Chunyang Mao, Rui Wang

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Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis by Yuliya V Yevsyutina, V. T. Ivashkin, E. Z. Abgadzhava

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Early pathohistological changes in dysfunction of arteriovenous fistula for hemodialysis by Stolić Radojica, Mitrović Slobodanka, Stolić Dragica, Mitić Nebojša

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Immunosuppressive cells in acute myeloid leukemia: mechanisms and therapeutic target by Mengnan Liu, Mengting Yang, Mengting Yang, Yue Qi, Yue Qi, Yuting Ma, Yuting Ma, Qulian Guo, Qulian Guo, Ling Guo, Ling Guo, Chunyan Liu, Chunyan Liu, Wenjun Liu, Wenjun Liu, Lan Xiao, Lan Xiao, You Yang, You Yang

“…This immunologically hostile niche is principally governed by specialized immunosuppressive cell populations—notably regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), leukemia-associated macrophages (LAMs), and regulatory B cells (Bregs)—which collectively establish an immune-privileged sanctuary for leukemic cells. …”
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Hydroxysteroid 17β‐dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high‐fat diet obese mice by Shehroz Mahmood, Nicola Morrice, Dawn Thompson, Sara Milanizadeh, Sophie Wilson, Philip D. Whitfield, George D. Mcilroy, Justin J. Rochford, Nimesh Mody

“…Abstract Hydroxysteroid 17β‐dehydrogenase 13 (HSD17B13) loss‐of‐function gene variants are associated with a decreased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD). …”
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T and NK cell functionality in a patient harboring heterozygous novel BCL11B p.Asp632fsAla∗91 and STX11 p.R129P mutations by Lorenzo Erra, Ana Colado, Franco Gino Brunello, Emma Prieto, Verónica Goris, Mariana Villa, Matías Oleastro, Marcelo Martí, Roberto Gabriel Pozner, Mercedes Borge, María Belén Almejun

“…BCL11B is a transcription factor essential for central nervous system development and T-cell differentiation that regulates numerous genes across various pathways. …”
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Oral administration of butylated hydroxytoluene induces neuroprotection in a streptozotocin-induced rat Alzheimer’s disease model via inhibition of neuronal ferroptosis by Parisa Faraji, Elham Parandavar, Hartmut Kuhn, Mehran Habibi-Rezaei, Astrid Borchert, Elham Zahedi, Shahin Ahmadian

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New insights toward personalized therapies for vulvovaginal candidiasis and vaginal co-infections by Francesco De Seta, Adilia Warris, Elena Roselletti

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Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review by Deenadhayalan Ashok, Monisha Prasad, Mohammad Fareed, Anis Ahmad Chaudhary

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Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice... by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

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An unexpected insight into the cause of olfactory dysfunction: fibrillogenesis of odorant-binding proteins by Olga V. Stepanenko, Maksim I. Sulatsky, Anna I. Sulatskaya, Olesya V. Stepanenko

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Macrophage Dysfunction in Tuberculosis–Diabetes Mellitus Comorbidity: A Scoping Review of Immune Dysregulation and Disease Progression by Simone E. Barry, Alice Sawka, Antonietta Maldari, Joseph Inauen, Sam LaBroome, James B. Geake

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Differentiation versus dysfunction: thyroid hormone, deiodinases and retinal photoreceptors by Lily Ng, Ye Liu, Young-Wook Cho, Hong Liu, Douglas Forrest

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Mitochondrial Dysfunction in Neurodegenerative Diseases: Mechanisms and Corresponding Therapeutic Strategies by Kai Meng, Haocheng Jia, Xiaoqing Hou, Ziming Zhu, Yuguang Lu, Yingying Feng, Jingwen Feng, Yong Xia, Rubin Tan, Fen Cui, Jinxiang Yuan

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FTO deficiency facilitates epithelia dysfunction in oral lichen planus by Yufeng Fan, Yukai Hao, Yan Ding, Xiangyu Wang, Xuejun Ge

“…At the molecular level, we explained that GSK-3β-induced phosphorylation promoted FTO protein degradation in diseased oral keratinocytes. Using a cell co-culture model, we further confirmed that FTO deficiency facilitated NF-κB activation and apoptosis in oral keratinocytes under inflammatory conditions. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

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Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction by LI Yi, REN Xinxin, WANG Qin, HE Xiaoyun

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Endothelial dysfunction as the main component of menopausal syndrome and cardiovascular diseases by D. D. Keshikova, O. K. Olshevskaya, L. D. Khidirova

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Recent Advances in Visual Dysfunction and Ocular Biomarkers in Neurological Disorders by Cheng J, Paracha SS, Agrawal S, Wu Z, Sung CH

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