Transcriptomics, Proteomics and Bioinformatics in Atrial Fibrillation: A Descriptive Review by Martina Belfiori, Lisa Lazzari, Melanie Hezzell, Gianni D. Angelini, Tim Dong

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Ischemia of the Eye on the Background of Primary Hypothyroidism and Primary Thyrotoxicosis by V. G. Likhvantseva, E. V. Korosteleva

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Sperm Proteomics: Road to Male Fertility and Contraception by Md Saidur Rahman, June-Sub Lee, Woo-Sung Kwon, Myung-Geol Pang

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Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI) by Jie Liu, Heleen vanBeusekom, Xian‐Le Bu, Gong Chen, Paulo Henrique Rosado de Castro, Xiaochun Chen, Xiaowei Chen, Andrew N. Clarkson, Tracy D. Farr, Yuhong Fu, Jianping Jia, Jukka Jolkkonen, Woojin Scott Kim, Paula Korhonen, Shen Li, Yajie Liang, Guang‐Hui Liu, Guiyou Liu, Yu‐Hui Liu, Tarja Malm, Xiaobo Mao, Joaquim Miguel Oliveira, Mike M. Modo, Pedro Ramos‐Cabrer, Karsten Ruscher, Weihong Song, Jun Wang, Xuanyue Wang, Yun Wang, Haitao Wu, Lize Xiong, Yi Yang, Keqiang Ye, Jin‐Tai Yu, Xin‐Fu Zhou, Marietta Zille, Colin L. Masters, Piotr Walczak, Johannes Boltze, Xunming Ji, Yan‐Jiang Wang

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Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence by Haryati Ahmad Hairi, Nurul Izzah Ibrahim, Muhammad Zulfiqah Sadikan, Putri Ayu Jayusman, Ahmad Nazrun Shuid

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Relaxation-exchange magnetic resonance imaging (REXI): a non-invasive imaging method for evaluating trans-barrier water exchange in the choroid plexus by Xuetao Wu, Qingping He, Yu Yin, Shuyuan Tan, Baogui Zhang, Weiyun Li, Yi-Cheng Hsu, Rong Xue, Ruiliang Bai

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Methylcobalamin-containing nanofiber sheets have better neuroprotective effects than small intestinal submucosa sheets by Yoshiaki Yoshimura, Toru Iwahashi, Taisuke Kasuya, Toshiki Shimada, Katsuyuki Konishi, Atsushi Kamata, Mai Konishi, Arisa Kazui, Ryoya Shiode, Satoshi Miyamura, Kunihiro Oka, Seiji Okada, Hiroyuki Tanaka

“…Abstract Postoperative adhesion around nerves sometimes results in sensory and motor dysfunctions. To prevent these disorders, we have developed an electrospun nanofiber sheet incorporating methylcobalamin (MeCbl), an active form of vitamin B12 with anti-inflammatory and neuroregenerative effects. …”
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The Role of Apelin in the Functioning of the Reproductive System by A. O. Shpakov, K. V. Derkach

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A biochemical screening platform to target chromatin states using condensates as a tool by Laura J. Hsieh, Tracy Lou, Muryam A. Gourdet, Emily Wong, Geeta J. Narlikar

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Endothelial monolayer disruption in bioprosthetic heart valve as a trigger of primary tissue failure by R. A. Mukhamadiyarov, N. V. Rutkovskaya, A. G. Kutikhin, I. V. Milto, O. D. Sidorova, L. S. Barbarash

“…The structure of BHV leaflets was studied by hematoxylin – eosin staining and immunohistochemistry assay (with the following indicators – CD3, T lymphocytes; CD20, B lymphocytes; CD31, mature endothelial cells; CD34, endothelial progenitor cells; CD68, monocytes/macrophages; vimentin, mesenchymal cells; α-smooth muscle actin, vascular smooth muscle cells).Results. …”
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Polyvinyl alcohol improves resistance of epoxy-treated bovine pericardium to calcification in vitro by A. E. Kostyunin, M. A. Rezvova, T. V. Glushkova, D. K. Shishkova, A. G. Kutikhin, T. N. Akentieva, E. A. Ovcharenko

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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

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Molecular Mechanisms of Hawthorn Extracts in Multiple Organs Disorders in Underlying of Diabetes: A Review by Izadpanah Gheitasi, Feryal Savari, Ghaidafeh Akbari, Jamshid Mohammadi, Ali Reza Fallahzadeh, Hossein Sadeghi

“…Based on this review, hawthorn extracts appear both therapeutic and protective effects against diabetic-related complications in various organs through molecular mechanisms, such as decreasing triglyceride, cholesterol, very low density lipoprotein and increasing the antioxidant activity of superoxide dismutase, catalase, glutathione peroxidase, total antioxidant capacity, decreasing malondialdehyde level, and attenuating tumor necrosis factor alpha, interleukin 6 and sirtuin 1/AMP-activated protein kinase (AMPK)/nuclear factor kappa B (NF-κB) pathway and increasing the phosphorylation of glucose transporter 4, insulin receptor substrate 1, AKT and phosphoinositide 3-kinases, and attenuating blood sugar and regulation of insulin secretion, insulin resistance, and improvement of histopathological changes in pancreatic beta cells. …”
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MicroRNA changes with macro potential contribute to secondary immunodeficiency in chronic lymphocytic leukemia during epstein barr virus reactivation by Paulina Mertowska, Sebastian Mertowski, Ewelina Grywalska

“…Comprehensive analyses included miRNA profiling, EBV infection markers, and the expression of PD-1, PD-L1, CTLA-4, CD200, and CD86 on CD4 + and CD8 + T cells, as well as CD19 + B cells. The results revealed significant suppression of tumor-suppressive miRNAs (e.g., miR-15a, miR-181a, and miR-29a) in the SID EBV + group, correlating with enhanced immunosuppression. …”
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The Association between Allergies and Hematologic Tumors — A Review by Aleksandra Hrapkowicz, Joanna Szydziak, Kinga Janowska, Olga Szeidl, Dominika Rehan, Julia Wołoszczak, Agnieszka Mioskowska , Daria Dąbkowska

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The Contribution of the Skin Microbiome to Psoriasis Pathogenesis and Its Implications for Therapeutic Strategies by Diana Sabina Radaschin, Alin Tatu, Alina Viorica Iancu, Cristina Beiu, Liliana Gabriela Popa

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The restoration of REST inhibits reactivity of Down syndrome iPSC-derived astrocytes by Tan Huang, Sharida Fakurazi, Pike-See Cheah, Pike-See Cheah, Pike-See Cheah, King-Hwa Ling, King-Hwa Ling, King-Hwa Ling

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miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis by Geurim Son, Yongwoo Na, Yongsung Kim, Ji-Hoon Son, Gregory D. Clemenson, Simon T. Schafer, Jong-Yeon Yoo, Sarah L. Parylak, Apua Paquola, Hyunsu Do, Dayeon Kim, Insook Ahn, Mingyu Ju, Chanhee S. Kang, Younghee Ju, Eunji Jung, Aidan H. McDonald, Youngjin Park, Gilhyun Kim, Se-Bum Paik, Junho Hur, Joon Kim, Yong-Mahn Han, Seung-Hee Lee, Fred H. Gage, Jong-Seo Kim, Jinju Han

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Long-term kidney complications in childhood leukemia survivors: a study from the Childhood and Adolescent Leukaemia (LEA) project by Carine Domenech, Paul Saultier, Zeinab Hamidou, Marie-Dominique Tabone, Marlène Pasquet, Virginie Gandemer, Stéphane Ducassou, Marilyne Poirée, Dominique Plantaz, Jean-Hugues Dalle, Pascal Chastagner, Sandrine Thouvenin, Justyna Kanold, Alexandre Theron, Isabelle Pellier, Yves Reguerres, André Baruchel, Pascal Auquier, Justine Bacchetta, Gérard Michel, Laurence Derain-Dubourg

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Galectin‐1‐Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs by Xizhi Yu, Junjie Qian, Limin Ding, Caixu Pan, Xi Liu, Qinchuan Wu, Shuai Wang, Jianpeng Liu, Mingge Shang, Rong Su, Danjing Guo, Haiyang Xie, Shengyong Yin, Lin Zhou, Shusen Zheng

“…Furthermore, RNA‐sequencing determined that Gal1 promoted the upregulation of chemokine (C‐C motif) ligand 20 (CCL20) in TAMs via activating the PI3K/AKT/NF‐κB pathway. Employing an anti‐CCL20 neutralizing antibody and Foxp3DTR mice, it is demonstrated that CCR6+Foxp3+ regulatory T cells (Tregs) recruited by Gal1‐induced TAMs contributed to reduced infiltration and dysfunctional state of CD8+ T cells, subsequently facilitating tumor progression. …”
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