P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY

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Angiogenic Factors and Inflammatory Bowel Diseases by Zhiru Li, Li Zeng, Wei Huang, Xinxing Zhang, Li Zhang, Qin Xie

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Sonic Hedgehog signaling in spinal cord injury: mechanisms and therapeutic implications by Mingjuan Du, Xiaozhen Ji, Weiting Chen

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Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic Stroke by Zhen Li, Xinyi He, Qi Fang, Xulong Yin

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Bilateral Streak Ovaries in a Patient with Isochromosome Xq: A Case Report of a Turner Syndrome Variant by Hartanto AI, Anwar R, Ismail M, Asmara EC, Adriansyah PNA

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Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice by Siyuan Sun, Yuanqi Liu, Jiping Sun, Bingxin Zan, Yiwen Cui, Anting Jin, Hongyuan Xu, Xiangru Huang, Yanfei Zhu, Yiling Yang, Xin Gao, Tingwei Lu, Xinyu Wang, Jingyi Liu, Li Mei, Lei Shen, Qinggang Dai, Lingyong Jiang

“…Results showed that hematopoietic progenitors and B lymphocyte differentiation were affected and the osteoblast-dominated cell crosstalk was impaired, which may result from transcriptional impairment of the ligands Pdgfd and Sema4d. …”
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Potential diagnostic and therapeutic gene in chronic low back pain through pyroptosis modulation: A silico study based on the dataset analysis by Jintao Guo, Tao Sun

“…Moreover, the investigation into immune cell infiltration revealed substantial disparities in the presence of five distinct immune cell types between the chronic LBP and acute LBP cohorts. …”
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Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. by Valentina Grampa, Marion Delous, Mohamad Zaidan, Gweltas Odye, Sophie Thomas, Nadia Elkhartoufi, Emilie Filhol, Olivier Niel, Flora Silbermann, Corinne Lebreton, Sophie Collardeau-Frachon, Isabelle Rouvet, Jean-Luc Alessandri, Louise Devisme, Anne Dieux-Coeslier, Marie-Pierre Cordier, Yline Capri, Suonavy Khung-Savatovsky, Sabine Sigaudy, Rémi Salomon, Corinne Antignac, Marie-Claire Gubler, Alexandre Benmerah, Fabiola Terzi, Tania Attié-Bitach, Cécile Jeanpierre, Sophie Saunier

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Reframing type 1 diabetes through the endocannabinoidome-microbiota axis: a systems biology perspective by Wojciech Łukowski

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Signaling pathways and targeted therapy for pulmonary hypertension by Joseph Adu-Amankwaah, Yue Shi, Hequn Song, Yixuan Ma, Jia Liu, Hao Wang, Jinxiang Yuan, Kun Sun, Qinghua Hu, Rubin Tan

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Bicuspid Aortic Valve Disease and Ascending Aortic Aneurysms: Gaps in Knowledge by Katie L. Losenno, Robert L. Goodman, Michael W. A. Chu

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MicroRNA-150 Deletion from Adult Myofibroblasts Augments Maladaptive Cardiac Remodeling Following Chronic Myocardial Infarction by Satoshi Kawaguchi, Marisa N. Sepúlveda, Jian-peng Teoh, Taiki Hayasaka, Bruno Moukette, Tatsuya Aonuma, Hyun Cheol Roh, Meena S. Madhur, Il-man Kim

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The Dual Role of Oxidative Stress in Atherosclerosis and Coronary Artery Disease: Pathological Mechanisms and Diagnostic Potential by Marcin Myszko, Jerzy Bychowski, Elżbieta Skrzydlewska, Wojciech Łuczaj

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A mini-review of nanoparticle therapeutics targeting oxidative stress and inflammation in diabetes by Naglaa A. Taha, Aida A. Hussein, Heba N. Gad El-Hak, Nahla S. El-Shenawy

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The Role of Fibroblasts in Dystrophic Epidermolysis Bullosa Pathogenesis and Current Treatment Approaches by Alexander Nyström, Celine Pattaroni, Johannes S. Kern

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Evaluation of the serum fasting insulin and HOMA-IR in diabetic and FDR patients by Dipalee Rahul Navale, Vaishali Shashil Patil

“…There is a relationship between fasting serum insulin, IR, and beta-cell dysfunction. Familial aggregation is a significant risk factor for early-onset type 2 diabetes mellitus. …”
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Astrocytes: Therapeutic targets for stroke by Jingxiu Li, Keyuan Gao, Lili Wang, Jiayue Wang, Mian Qin, Xinrui Wang, Kai Lian, Chao Li, Shan’e Gao, Chenxi Sun

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Targeting Ischemia-reperfusion injury in liver transplant rejuvenation by Kenneth J. Dery, Fady Kaldas, Jerzy W. Kupiec-Weglinski

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Ferroptosis-associated pathological injury mechanisms and therapeutic strategies after intracerebral hemorrhage by Yuhua Gong, Yuhua Gong, Fumei Yang, Ying Liu, Yuping Gong

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Immune-checkpoint inhibitors for glioblastoma: what have we learned? by Antonio Omuro

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