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    MULTI-TYROSINE KINASE INHIBITOR-ASSOCIATED APLASTIC ANEMIA AND A BRIEF LITERATURE REVIEW by Veysel Erol, Zeki Guzel, Mustafa Gokoglu

    Published 2024-12-01
    “…This was followed by the development of second-generation (dasatinib, nilotinib, bosutinib) and third-generation (ponatinib) TKIs, which greatly improved disease outcomes and significantly reduced TKI resistance.Common side effects of TKIs include pleural/pericardial effusion, pretibial edema, hyperglycemia, hyperlipidemia, liver dysfunction, diarrhea, and thrombosis, most of which can be managed by temporarily discontinuing the drug or reducing the dosage. …”
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