Advances in primary large B-cell lymphoma of immune-privileged sites by Liao Wang, Liao Wang, Meiru Guo, Shuling Hou, Shuling Hou, Shuling Hou

“…Primary large B-cell lymphoma of immune-privileged sites (IP-LBCL) encompasses a spectrum of relatively rare aggressive B-cell lymphomas, such as primary central nervous system lymphoma (PCNSL), primary testicular large B-cell lymphoma (PTL), and primary vitreoretinal large B-cell lymphoma (PVRL). …”
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Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen. by Johanna A Knipper, Alasdair Ivens, Matthew D Taylor

“…This indicates a novel regulatory role for IL-21 during filarial infection, both in controlling protection and B cell responses. Thus, Th2 cell-intrinsic hypo-responsiveness is a distinct and stable state of Th2 cell differentiation associated with a switch from a classically active IL-4+IL-5+ Th2 phenotype, to a non-classical dysfunctional and potentially regulatory IL-21+Egr2+c-Maf+Blimp-1+IL-4loIL-5loT-bet+IFN-γ+ Th2 phenotype. …”
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Molecular Mechanisms of Rett Syndrome: Emphasizing the Roles of Monoamine, Immunity, and Mitochondrial Dysfunction by Julia Lopes Gonçalez, Jenny Shen, Wei Li

“…Furthermore, the immune system in RTT individuals demonstrates dysfunction through the abnormal activity of microglia, macrophages, lymphocytes, and non-immune cells, leading to the atypical release of inflammatory mediators and disruptions in the NF-κB signaling pathway. …”
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Bile acid disorders and intestinal barrier dysfunction are involved in the development of fatty liver in laying hens by Lihua Zhao, Qiuyu Jiang, Jiaqi Lei, Jian Cui, Xianjie Pan, Yuan Yue, Bingkun Zhang

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Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosis by Suqi Liu, Qian Xi, Xuannian Li, Huaman Liu

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The gut-heart axis: a correlation between Paneth cells’ dysfunction, microbiome dysbiosis, and cardiovascular diseases by Aysa Rezabakhsh, Solomon Habtemariam, Rezayat Parvizi, Anne Meddahi-Pellé, Violeta Rodriguez Ruiz, Graciela Pavon-Djavid, Abolfazl Barzgari

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Analyzing the Current Umbilical Cord-derived Mesenchymal Stem Cell Secretome Evidence for Erectile Dysfunction Management by Ria Margiana, Muhammad Fadhli Abdullah, Cennikon Pakpahan, Reny I'tishom, Supardi Supardi, Huriyah Adani Saoemi, Nguyen Hoai Bac

“…Included among the search queries were "erectile dysfunction," "stem cells," "mesenchymal stem cells," "umbilical cord," and "secretome." …”
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Urinary Transforming Growth Factor β-1 as a Marker of Renal Dysfunction in Sickle Cell Disease by Emad E. Ghobrial, Hanan A. Abdel-Aziz, Ahmed M. Kaddah, Nesma A. Mubarak

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Natural killer cell in the development and treatment of head and neck squamous cell carcinoma by Lu-Ming WANG, Shang XIE

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Inhibition of Cbl-b restores effector functions of human intratumoral NK cells by Alfred Zippelius, Mélanie Buchi, Petra Herzig, Heinz Läubli, Kirsten D Mertz, Viola Heinzelmann-Schwarz, Didier Lardinois, Marina Natoli, Clara Serger, Alberto Toso, Nicole Brodmann, Sofia Tundo, Marcel Trefny, Andrijana Rodić, Olivia Grueninger, Anastasiya Börsch, Jonas Fürst, Katarzyna Buczak, Alex T Müller, Lisa Sach-Peltason, Leyla Don, Aljaž Hojski, Karin Schaeuble, Thuy T Luu, Andrea Romagnani

“…Furthermore, the Cbl-b inhibitor was able to reinvigorate the activity of in vitro generated and patient-derived dysfunctional NK cells. …”
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PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link

“…The successful use of rituximab underscores the relevance of B-cell–directed immunosuppression in managing such complex cases, particularly in the context of clonal B-cell disorders. …”
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Signaling through the nicotinic acetylcholine receptor in the liver protects against the development of metabolic dysfunction-associated steatohepatitis. by Heejin Jun, Shanshan Liu, Alexander J Knights, Kezhou Zhu, Yingxu Ma, Jianke Gong, Ashley E Lenhart, Xiaoling Peng, Yunying Huang, Jared P Ginder, Christopher H Downie, Erika Thalia Ramos, Klas Kullander, Robert T Kennedy, X Z Shawn Xu, Jun Wu

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Development and validation of a predictive model for postoperative hepatic dysfunction in Stanford type A aortic dissection by Xiaotian Han, Wei Wang, Tianxiang Gu, Enyi Shi

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Dual Role of Lysosome in Cancer Development and Progression by Xiao-Qiong Chen, Quan Yang, Wei-Min Chen, Zi-Wei Chen, Guang-Hui Guo, Xuan Zhang, Xiao-Ming Sun, Tao Shen, Fu-Hui Xiao, Yun-Feng Li

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Abnormal proportions and functions of myeloid-derived suppressor cells in peripheral blood of patients with diffuse large B-cell lymphoma by Jingru Liu, Shucheng Chen, Yanrong Huang, Kaiming Xu, Maoqing Tan, Wei Dai, Xiaoting Wang, Diyu Hou, Shuxia Zhang, Jiadi Chen, Huifang Huang

“…Evidence suggests that abnormal immune system can lead to immune dysfunction and increase the risk of developing diffuse large B-cell lymphoma (DLBCL). …”
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Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection by Xiu Liu, Li Zhao, Deshen Liu, Lingna Zhao, Yonghua Tuo, Qinbao Peng, Fangze Huang, Zhengkun Song, Chuanjie Niu, Xiaoxia He, Yu Xu, Jun Wan, Peng Zhu, Zhengyang Jian, Jiawei Guo, Yingying Liu, Jun Lu, Sijia Liang, Shaoyi Zheng

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Unraveling the interplay of CD8 + T cells and microRNA signaling in cancer: implications for immune dysfunction and therapeutic approaches by Arefeh Zabeti Touchaei, Sogand Vahidi

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Natural Killer Cell Dysfunction in Obese Patients with Breast Cancer: A Review of a Triad and Its Implications by Esraa Elaraby, Abdullah Imadeddin Malek, Hanan W. Abdullah, Noha Mousaad Elemam, Maha Saber-Ayad, Iman M. Talaat

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Disproportionately Elevated Proinsulin Levels as an Early Indicator of β-Cell Dysfunction in Nondiabetic Offspring of Chinese Diabetic Patients by Ming Li, Dan Feng, Kui Zhang, Shan Gao, Juming Lu

“…Compared with HOMA-B, FPI/SI could detect β-cell failure in earlier stage of diabetes development.…”
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Nanovaccine loaded with seno-antigen target senescent cells to improve metabolic disorders of adipose tissue and cardiac dysfunction by Kexin Zhang, Qiliang Yin, Yucen Ma, Mengyu Cao, Lingwei Li, Xinliang Jin, Jiyan Leng

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