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    Intrinsic factors behind long COVID: exploring the role of nucleocapsid protein in thrombosis by Ahmed Eltayeb, Muhamed Adilović, Maryam Golzardi, Altijana Hromić-Jahjefendić, Alberto Rubio-Casillas, Vladimir N. Uversky, Elrashdy M. Redwan

    Published 2025-05-01
    “…While NPs from other coronaviruses, such as SARS-CoV and MERS-CoV, are known to increase inflammation and cause acute lung injury, the specific effects of the SARS-CoV-2 NP on host cells remain largely unexplored. Recent findings suggest that the NP acts as a pathogen-associated molecular pattern (PAMP) that binds to Toll-like receptor 2 (TLR2), activating NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) and MAPK (mitogen-activated protein kinase) signaling pathways. …”
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    Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy by Guangjian Hou, Youzi Dong, Yuehua Jiang, Wenbo Zhao, Le Zhou, Shengnan Cao, Wei Li

    Published 2025-07-01
    “…The immune system, particularly macrophages, T cells, and B cells, plays a crucial role in the progression of kidney injury, with inflammatory cytokines such as TNF-α and IL-6 promoting renal inflammation and fibrosis. …”
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