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Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding
Published 2024-12-01Get full text
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CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis
Published 2025-03-01Get full text
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Klotho in age-related cardiovascular diseases: Insights into mitochondrial dysfunction and cell death
Published 2025-04-01Get full text
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Alveolar epithelial cell dysfunction and epithelial-mesenchymal transition in pulmonary fibrosis pathogenesis
Published 2025-04-01“…Pulmonary fibrosis (PF) is a progressive and lethal interstitial lung disease characterized by aberrant scar formation and destruction of alveolar architecture. Dysfunctional alveolar epithelial cells (AECs) play a central role in initiating PF, where chronic injury triggers apoptosis and disrupts epithelial homeostasis, leading to epithelial-mesenchymal transition (EMT). …”
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Humanized monoacylglycerol acyltransferase 2 mice develop metabolic dysfunction-associated steatohepatitis
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Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson DiseaseSummary
Published 2025-01-01“…Methods: The splicing assay and RNA pull-down were performed to explore the mechanism of the aberrant splicing. The ATP7B knockout HuH-7 cell line and Atp7b-/- mice were created, and the functional consequence of the mutant ATP7B were evaluated in vitro and in vivo. …”
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Involvement of Oxidative Stress in Mitochondrial Abnormalities During the Development of Heart Disease
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Clinicopathological analysis of adrenal intravascular large B-cell lymphoma
Published 2024-11-01“…Background and purpose: Primary adrenal intravascular large B-cell lymphoma (IVLBCL) is rare and highly aggressive. …”
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CASE REPORT: SIMULTANEOUS OCCURRENCE OF PLASMA AND B CELL MALIGNANCY
Published 2024-12-01“…Objective: Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) are two distinct hematological malignancies thought to arise at different stages of the B cell maturation pathway.Here, we aimed to present our approach to such a patient. …”
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Blockade of TIGAR prevents CD8+ T cell dysfunction and elicits anti-AML immunity
Published 2025-04-01“…This study aims to investigate whether TIGAR silencing in host can eliminate AML cells and rejuvenate dysfunctional T cells with mouse models. …”
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A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
Published 2018-01-01Get full text
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Nanopathways modulating postoperative cognitive dysfunction: extracellular vesicles
Published 2025-06-01Get full text
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Baseline echocardiographic variables as predictors of hemodynamically significant cytokine release syndrome in adults treated with CD19 CAR T-cell therapy for hematological maligna...
Published 2024-12-01“…Abstract Background CD19 CAR T-cell therapy is a novel anti-cancer treatment that has produced remarkable responses in relapsed or refractory B-cell hematological malignancies. …”
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