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    Alveolar epithelial cell dysfunction and epithelial-mesenchymal transition in pulmonary fibrosis pathogenesis by Caopei Zheng, Caopei Zheng, Ling Zhang, Ling Zhang, Yuqing Sun, Yuqing Sun, Yingmin Ma, Yulin Zhang, Yulin Zhang, Yulin Zhang

    Published 2025-04-01
    “…Pulmonary fibrosis (PF) is a progressive and lethal interstitial lung disease characterized by aberrant scar formation and destruction of alveolar architecture. Dysfunctional alveolar epithelial cells (AECs) play a central role in initiating PF, where chronic injury triggers apoptosis and disrupts epithelial homeostasis, leading to epithelial-mesenchymal transition (EMT). …”
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    Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson DiseaseSummary by Donghu Zhou, Huaduan Zi, Xiaoxi Yang, Xiaojin Li, Yanmeng Li, Anjian Xu, Bei Zhang, Wei Zhang, Xiaojuan Ou, Jidong Jia, Jian Huang, Hong You

    Published 2025-01-01
    “…Methods: The splicing assay and RNA pull-down were performed to explore the mechanism of the aberrant splicing. The ATP7B knockout HuH-7 cell line and Atp7b-/- mice were created, and the functional consequence of the mutant ATP7B were evaluated in vitro and in vivo. …”
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    Clinicopathological analysis of adrenal intravascular large B-cell lymphoma by LIN Jiaxin, WEI Ran, SHUI Ruohong, LU Hongfen, LI Xiaoqiu, YU Baohua

    Published 2024-11-01
    “…Background and purpose: Primary adrenal intravascular large B-cell lymphoma (IVLBCL) is rare and highly aggressive. …”
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    CASE REPORT: SIMULTANEOUS OCCURRENCE OF PLASMA AND B CELL MALIGNANCY by Nigar Abdullayeva, Damla Cagla Patır, Selin Kır, Ali Yılmazer, Derya Demir, Mehmet Soylu, Mahmut Töbü

    Published 2024-12-01
    “…Objective: Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) are two distinct hematological malignancies thought to arise at different stages of the B cell maturation pathway.Here, we aimed to present our approach to such a patient. …”
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    Blockade of TIGAR prevents CD8+ T cell dysfunction and elicits anti-AML immunity by Jialin Cui, Wenjie Liu, Shiyang Zhong, Yiran Fang, Pei Xu, Cheng Xu, Rong Wang, Xingfei Hu, Wanting Zhou, Kening Li, Ming Hong, Sixuan Qian, Qian Sun

    Published 2025-04-01
    “…This study aims to investigate whether TIGAR silencing in host can eliminate AML cells and rejuvenate dysfunctional T cells with mouse models. …”
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