Endothelial Cell Senescence in Marfan Syndrome: Pathogenesis and Therapeutic Potential of TGF‐β Pathway Inhibition by Yuhao Chen, Yuankang Zhu, Xiaoli Ren, Lu Ding, Yubin Xu, Miqi Zhou, Runze Dong, Peifeng Jin, Xiufang Chen, Xiaofang Fan, Ming Li, Yongsheng Gong, Yongyu Wang

“…This study aims to elucidate the role of EC senescence in the development of aortic aneurysms in MFS using a vascular model derived from human induced pluripotent stem cells. …”
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Targeted regulatory T cell activation by site-specific PEGylated interleukin-2 mitigates autoimmune inflammation by Masahiro Ikeda, Shinpei Yamaguchi, Shigeki Takaoka, Yasuko Sakaguchi, Shunki Yasui

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Alveolar epithelial cells in bacterial sepsis-associated acute lung injury: mechanisms and therapeutic strategies by Guiyang Jia, Guiyang Jia, Erqin Song, Zhiyou Zheng, Mingjiang Qian, Guoyue Liu

“…It elaborates on the regulatory mechanisms of key molecular pathways, including Nuclear factor kappa-B (NF-κB), Nuclear Factor Erythroid 2-related Factor 2 (NRF2), nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3), and Toll-like receptor (TLR), in AEC dysfunction and inflammatory responses. …”
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Inhibiting Ferroptosis Prevents the Progression of Steatotic Liver Disease in Obese Mice by Gi Cheol Park, Soo-Young Bang, Ji Min Kim, Sung-Chan Shin, Yong-il Cheon, Kwang Min Kim, Hanaro Park, Eui-Suk Sung, Minhyung Lee, Jin-Choon Lee, Byung-Joo Lee

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Network Pharmacology Approaches to Myocardial Infarction Reperfusion Injury: Exploring Mechanisms, Pathophysiology, and Novel Therapies by Joy Das, Ashok Kumar Sah, Ranjay Kumar Choudhary, Rabab H. Elshaikh, Utpal Bhui, Shreya Chowdhury, Anass M. Abbas, Manar G. Shalabi, Nadeem Ahmad Siddique, Raji Rubayyi Alshammari, Navjyot Trivedi, Khoula Salim Ali Buwaiqi, Said Al Ghenaimi, Pranav Kumar Prabhakar

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Identification and experimental validation of biomarkers associated with mitochondrial and programmed cell death in major depressive disorder by Shengjie Xiong, Lixin Liao, Meng Chen, Qing Gan

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PECULIARITIES OF SYSTEMIС INFLAMMATION OF LOW INTENSITY IN PATIENTS WITH STABLE CORONARY HEART DISEASE CONCURRENT WITH NON-ALCOHOLIC FATTY LIVER DISEASE by Yu.I. Manusha, Yu.M. Kazakov, Т.А. Trybrat, K.E. Ischeykin

“…We studied the level of expression of the mRNA gene of IkBα in mononuclear cells, which reflects the level of transcriptional activity of NF-kB in patients with stable coronary artery disease and CHD in combination with NAFLD showed a significant increase in the expression of the mRNA gene of IkBα by 88.5% compared to patients with stable stable coronary heart disease. …”
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Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function by Kazuya Ono, Amandine Jarysta, Natasha C Hughes, Alma Jukic, Hui Ho Vanessa Chang, Michael R Deans, Ruth Anne Eatock, Kathleen E Cullen, Katie S Kindt, Basile Tarchini

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Human induced pluripotent stem cells derived neutrophils display strong anti-microbial potencies by Xing Hu, Baoqiang Kang, Mingquan Wang, Huaisong Lin, Zhiyong Liu, Zhishuai Zhang, Jiaming Gu, Yuchan Mai, Xinrui Guo, Wanli Ma, Han Yan, Shuoting Wang, Jingxi Huang, Junwei Wang, Jian Zhang, Tianyu Zhang, Bo Feng, Yanling Zhu, Guangjin Pan

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NKG2D triggering hampers DNAM-1-mediated signaling in human NK cells by Caterina Marangio, Nadia Domenica Milito, Erisa Putro, Alessia Carnevale, Cristina Capuano, Alessandra Zingoni, Marco Cippitelli, Angela Santoni, Angela Santoni, Rossella Paolini, Rosa Molfetta

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Oral microbiome-derived biomarkers for non-invasive diagnosis of head and neck squamous cell carcinoma by Jingtai Zhi, Yibo Liang, Wang Zhao, Jie Qiao, Yongzhe Zheng, Xin Peng, Li Li, Xianfeng Wei, Wei Wang

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Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis. by Dequina Nicholas, Elizabeth A Proctor, Forum M Raval, Blanche C Ip, Chloe Habib, Eleni Ritou, Tom N Grammatopoulos, Devin Steenkamp, Hans Dooms, Caroline M Apovian, Douglas A Lauffenburger, Barbara S Nikolajczyk

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Identification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics. by Jaime Moreno, Lise Lotte Gluud, Elisabeth D Galsgaard, Henning Hvid, Gianluca Mazzoni, Vivek Das

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Improving retinal vascular endothelial cell tropism through rational rAAV capsid design. by Ramesh Periasamy, Dwani D Patel, Sanford L Boye, Shannon E Boye, Daniel M Lipinski

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Cellular and Molecular Interactions in CNS Injury: The Role of Immune Cells and Inflammatory Responses in Damage and Repair by Jai Chand Patel, Meenakshi Shukla, Manish Shukla

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HE ROLE OF FATTY ACID CONTENTS OF ERYTHROCYTES MEMBRANES IN CARDIOHEMODYNAMICS DISORDER IN GOUT PATIENTS WITH INSULIN RESISTANCE SYNDROME by N. N. Kushnarenko, T. A. Medvedeva, A. V. Govorin, M. Yu. Mishko

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A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity by Matias G. Perez, Victoria Gillan, William M. Anderson, François Gerbe, Fabien Herbert, Tom N. McNeilly, Rick M. Maizels, Philippe Jay, Eileen Devaney, Collette Britton

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GFR is a Key Determinant of Red Blood Cell Survival in Anemia Associated With Progressive CKD by Rosi Bissinger, Lina Schaefer, Bernhard N. Bohnert, Anja Schork, Sebastian Hoerber, Andreas Peter, Syed M. Qadri, Andreas L. Birkenfeld, Nils Heyne, Tamam Bakchoul, Thomas Wieder, Ferruh Artunc

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Integral kidney function assessment in pediatric patients with glycogen storage diseases by Magali Reyes-Apodaca, Magali Reyes-Apodaca, Alejandra Consuelo-Sánchez, Rodrigo Vázquez-Frias, Rodrigo Vázquez-Frias, Benjamín Antonio Rodríguez-Espino, Mara Medeiros, Mara Medeiros

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Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond by Aref Yarahmadi, Masoumeh Dorri Giv, Reza Hosseininejad, Azin Rezaie, Narges Mohammadi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Arastoo Farokhi

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