The role of endoplasmic reticulum stress in type 2 diabetes mellitus mechanisms and impact on islet function by Zhaxicao He, Qian Liu, Yan Wang, Bing Zhao, Lumei Zhang, Xia Yang, Zhigang Wang

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Age-related changes in the immune system and challenges for the development of age-specific vaccines by T. Mark Doherty, Birgit Weinberger, Arnaud Didierlaurent, Paul-Henri Lambert

“…Immunosenescence affects T-cell and B-cell populations and innate immunity, leading to reduced chemotaxis, cytotoxicity, and altered cytokine production. …”
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Rewiring the seizing brain: stem cell grafts as neuromodulatory architects in epilepsy therapy by Zijie Wang, Yanan Ma, Xiqi Hu, Ying Xia

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Etiological and immunopathogenetic aspects of multiorgan failure development in coronavirus disease (COVID-19) by T. V. Ashcheulova, N. M. Herasymchuk, O. A. Kochubiei, U. S. Herasymchuk

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Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells. by Matthew E Gegg, J Mark Cooper, Anthony H V Schapira, Jan-Willem Taanman

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Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma by Xuri Zhao, Yaping Zhu, Youya He, Weiyan Gu, Qi Zhou, Bei Jin, Shenguo Chen, Haisheng Lin

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Replicative Senescence in Mesenchymal Stem Cells: An In Vitro Study on Mitochondrial Dynamics and Metabolic Alterations by Beatrice Casorati, Isabella Zafferri, Sara Castiglioni, Jeanette A. Maier

“…These mitochondrial defects play a role in metabolic reprogramming in senescent bMSCs. Our findings underscore the intricate interplay between ROS, mitochondrial dysfunction, and replicative senescence, offering valuable insights to guide the development of therapeutic strategies for preserving MSC functionality in aging and MSC-based therapies.…”
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Immune and Extracellular Matrix Dynamics in Chronic Endometritis: Insights into Endometrial Homeostasis and Fibrogenic Niche Evolution by S. A. Mikhalev, M. A. Kurtser, V. E. Radzinsky, Narasimha M. Beeraka, A. A. Kostin, D. A. Atiakshin, M. R. Orazov, L. M. Mikhaleva

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Blue light-induced phototoxicity in retinal cells: implications in age-related macular degeneration by Harshini Chakravarthy, Vasil Georgyev, Cole Wagen, Amir Hosseini, Joanne Matsubara

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Interleukin-37: The Effect of Anti-Inflammatory Response in Human Coronary Artery Endothelial Cells by Xianfeng Yan, Bin Xie, Guihai Wu, Jing Hu, Di Wang, Xiangna Cai, Jilin Li

“…IL-37 shows definite groups and transcripts for human IL37 gene, but it is still not completely understood the effect and mechanisms of inflammatory response in endothelial cells. It is well accepted that endothelial dysfunction caused by inflammation is a key initiating event in atherosclerotic plaque formation, which leads to the occurrence and development of the cardiovascular adverse events in clinical since the inflammatory responses of endothelial cells could induce and enhance the deposition of extensive lipid and the formation of atherosclerotic plaque in the intima. …”
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A Severe Alzheimer’s Disease Patient Improved by Intravenous Mesenchymal Stem Cell Transplant by Takahiro Honda Pazili

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Single-cell RNA sequencing reveals the effects of hederasaponin C in the treatment of diabetic nephropathy by Jing Liu, Qian Zhang, Wentong Zhao, Jinan Guo, Yin Kwan Wong, Chunting Zhang, Weijin Qiu, Piao Luo, Junhui Chen, Junmao Li, Xiaoran Li, Hongwei Gao, Shilin Yang, Yulin Feng, Jigang Wang

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Research of subpopulation CD3+ CD4- CD8- double-negative T lymphocytes in kidney transplant recipients by S. V. Zybleva, S. L. Zyblev

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Transcriptomic profiling of cumulus cells reveals dysregulated genes and pathways in PCOS-related infertility by Akeem Babatunde Sikiru, Nurulfiza Mat Isa, Kasim Sakran Abass, Muibat Adesola Adeniran, Stephen Sunday Acheneje Egena, Karimot Akinola

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High-fat diet and neuroinflammation: The role of mitochondria by Mingxue Song, Yao Bai, Fuyong Song

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Enhanced allergic Eustachian tube response in surfactant protein D knockout mice induced by ovalbumin by Xuan Yu, Hejie Li, Wei Tang, Xi Lian, Wenting Yu, Ting Li, Shimin Zong, Hongjun Xiao

“…Abnormal overexpression of Muc5ac and Muc5b may further exacerbate OVA-induced ET dysfunction. …”
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Pdia4 regulates β‐cell pathogenesis in diabetes: molecular mechanism and targeted therapy by Tien‐Fen Kuo, Shuo‐Wen Hsu, Shou‐Hsien Huang, Cicero Lee‐Tian Chang, Ching‐Shan Feng, Ming‐Guang Huang, Tzung‐Yan Chen, Meng‐Ting Yang, Si‐Tse Jiang, Tuan‐Nan Wen, Chun‐Yen Yang, Chung‐Yu Huang, Shu‐Huei Kao, Keng‐Chang Tsai, Greta Yang, Wen‐Chin Yang

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The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment by Fan Chen, Na Wang, Xinyan Tian, Juan Su, Yan Qin, Rongqiao He, Xiaping He

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Clinical application of mesenchymal stem cells in immunosenescence: a qualitative review of their potential and challenges by Xu Wang, Dan Guo, Chengmei He, Xiaoxi Wang, Yi Wei, Fengchun Zhang, Li Wang, Yanlei Yang

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A Very Rare Case of Hypereosinophilic Syndrome Secondary to Natural Killer/T-Cell Lymphoma by Takanori Yamamoto, Atsushi Kamijo, Tadao Nakazawa, Kei Nakajima, Keita Kirito, Norio Komatsu, Keisuke Masuyama

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