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    Nurr1 deficiency impairs autophagy-lysosomal function through GBA-dependent transcriptional regulation in Parkinson’s disease pathogenesis by Cheng Cheng, Cheng Cheng, Huijia Yang, Lulu Tian, Yang Ni, Congcong Jia, Weidong Le, Qingshan Wang

    Published 2025-06-01
    “…Transmission electron microscopy observation was conducted to find the ultrastructure differences between the Nurr1 knockdown cells and the controls. The expression of LC3B and the colocalization of LC3B and Lamp1 were assessed. …”
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    SPTBN1 overexpression ameliorates atherosclerosis by inhibiting oxidative stress and inflammation via regulating the TRIM37/TRAF2/NF-κB pathway by Senyan Wu, Xiaoni Tan, Guobing Cheng

    Published 2025-08-01
    “…Conclusion SPTBN1 overexpression suppressed apoptosis, oxidative stress, and inflammation in ox-LDL-treated HUVECs by regulating the TRIM37/TRAF2/NF-κB pathway, thereby inhibiting AS development in mice. …”
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    The Opportunities and Challenges regarding Induced Platelets from Human Pluripotent Stem Cells by Meng-Xue Xu, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

    Published 2021-01-01
    “…The development of new gene-editing techniques, such as CRISPR/Cas9, can be used to solve allogeneic immunity of platelet transfusions by knocking out the expression of B2M. …”
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