Organelle symphony: Nuclear factor erythroid 2-related factor 2 and nuclear factor-kappa B in stroke pathobiology by Ziliang Hu, Mingyue Zhao, Hangyu Shen, Liangzhe Wei, Jie Sun, Xiang Gao, Yi Huang

“…Nuclear factor-kappaB contributes to neuronal injury, apoptosis, and immune responses following stroke by modulating cell adhesion molecules and inflammatory mediators. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

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Bone Mineral Turnover after Allogeneic Hematopoietic Stem Cell Transplantation in Children: A Single Center Cohort Study by Yuliya V. Skvortsova, Dmitriy N. Balashov, Elena V. Skorobogatova, Zhanna B. Shekhovtsova, Kirill A. Voronin, Alexei A. Maschan

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Changes in VEGFR1 and VEGFR2 expression and endothelial cell maturity in laboratory animals with a model of Alzheimer’s disease by M. V. Kukla, A. S. Averchuk, A. V. Stavrovskaya, N. A. Rozanova, A. K. Berdnikov, N. A. Kolotyeva, A. B. Salmina

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Salvianolic Acid B Alleviates LPS-Induced Spleen Injury by Remodeling Redox Status and Suppressing NLRP3 Inflammasome by Hao Wang, Xiao Dou, Ruixue Wang, Yuxin Jiang, Jinsong Zhang, Xianjuan Qiao, Yingjun Liu, Hao Zhang, Chenhuan Lai, Yanan Chen, Qiang Yong

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The role of endothelial cell–pericyte interactions in vascularization and diseases by Gan Li, Junjie Gao, Peng Ding, Youshui Gao

“…Dysfunctional communication between these cells is associated with various diseases, including vascular diseases, central nervous system disorders, and certain types of cancers. …”
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Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice by Ya Gao, Jiayun Guan, Rui Zhou, Zewei Li, Tianyang Chen, Kaican Yang, Rong Huang, Yue Huang, Siting Zheng, Zhenhua Huang, Xiaoxiang Rong

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Transcriptomic and electrophysiological alterations underlying phenotypic variability in SCN1A-associated febrile seizures by Stefania Scalise, Alessandro Gaeta, Elio Aprigliano, Valeria Lucchino, Raffaele Covello, Mariagrazia Talarico, Barbara Puccio, Pietro Hiram Guzzi, Pierangelo Veltri, Antonio Gambardella, Lilian Juliana Lissner, Alessandra Morano, Pierangelo Cifelli, Veronica Alfano, Eleonora Palma, Gerardo Perozziello, Gabriele Ruffolo, Giovanni Cuda, Elvira Immacolata Parrotta

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Programmed Host Cell Death and Infectious Process of Mycoplasma by Alaa Abed, Ali Al-Iedani, Ahmed Neamah

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The Mechanical Role of YAP/TAZ in the Development of Diabetic Cardiomyopathy by Jun-Xian Shen, Ling Zhang, Huan-Huan Liu, Zhen-Ye Zhang, Ning Zhao, Jia-Bin Zhou, Ling-Ling Qian, Ru-Xing Wang

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Circulating programmed death-1 as a marker for sustained high hepatitis B viral load and risk of hepatocellular carcinoma. by Hsiang-Yun Cheng, Pei-Jen Kang, Ya-Hui Chuang, Ya-Hui Wang, Meng-Chin Jan, Chih-Feng Wu, Chih-Lin Lin, Chun-Jen Liu, Yun-Fan Liaw, Shi-Ming Lin, Pei-Jer Chen, Shou-Dong Lee, Ming-Whei Yu

“…<h4>Objective</h4>Recent evidence indicates a crucial role of the immunoinhibitory receptor programmed death-1 (PD-1) in enforcing T-cell dysfunction during chronic viral infection and cancer. …”
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Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection. by Matthias Hoffmann, Nikos Pantazis, Genevieve E Martin, Stephen Hickling, Jacob Hurst, Jodi Meyerowitz, Christian B Willberg, Nicola Robinson, Helen Brown, Martin Fisher, Sabine Kinloch, Abdel Babiker, Jonathan Weber, Nneka Nwokolo, Julie Fox, Sarah Fidler, Rodney Phillips, John Frater, SPARTAC and CHERUB Investigators

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Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants by Michelle R. Garnsey, Yang Wang, David J. Edmonds, Matthew F. Sammons, Benjamin Reidich, Youngwook Ahn, Yotam Ashkenazi, Anthony Carlo, Matthew A. Cerny, Karen J. Coffman, Jeffrey A. Culver, Anne-Marie Dechert Schmitt, Heather Eng, Ethan L. Fisher, Jemy A. Gutierrez, Larry James, Samantha Jordan, Jeffrey T. Kohrt, Melissa Kramer, Erik A. LaChapelle, Jack C. Lee, Jisun Lee, Dongmei Li, Zhenhong Li, Shenping Liu, Jianhua Liu, Thomas V. Magee, Melissa R. Miller, Michael Moran, Deane M. Nason, Nicole L. Nedoma, Steven V. O’Neil, Mary A. Piotrowski, Jillian Racich, Ruth F. Sommese, Lucy M. Stevens, Ann S. Wright, Jun Xiao, Liying Zhang, Dahui Zhou, Ornella Barrandon, Michelle F. Clasquin

“…However, over 5 years later, the function of 17B-HSD13 remains unknown. Structure-aided design enables the development of potent and selective sulfonamide-based 17B-HSD13 inhibitors. …”
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Single-cell atlas of endothelial cells in atherosclerosis: identifying C1 CXCL12+ ECs as key proliferative drivers for immunological precision therapeutics in atherosclerosis by Zhenzhen Zhao, Yujiang Dong, Zhijie Zhao, Zhikai Xiahou, Cong Sun

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RNA modifications: emerging players in the regulation of reproduction and development by Wen Junfei, Zhu Qifan, Liu Yong, Gou Lan-Tao

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A 3D Composite Model Using Electrospinning Technology to Study Endothelial Damage by Carmen Ciavarella, Luana Di Lisa, Gianandrea Pasquinelli, Maria Letizia Focarete, Sabrina Valente

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Conjugated bile acids promote metabolic dysfunction-associated steatotic liver disease through inducing nuclear translocation of sphingosine-1-phosphate receptor 2 to disrupt perox... by Rong-Rong Miao, Ming-Yong Tan, Han-Bing Shao, Zhi-Meng Sun, Sheng Zhan, Wei-Shi Liang, Xiao-Hui Liu, Ke-Qin Li, Yu-Yao Cheng, Xin-Feng Wu, Rui Xu, Shu-Xiang Cui, Yong Hai, Xian-Jun Qu

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Consortium of <i>Lactobacillus crispatus</i> 2029 and <i>Ligilactobacillus salivarius</i> 7247 Strains Shows In Vitro Bactericidal Effect on <i>Campylobacter jejuni</i> and, in Com... by Vyacheslav M. Abramov, Igor V. Kosarev, Andrey V. Machulin, Evgenia I. Deryusheva, Tatiana V. Priputnevich, Alexander N. Panin, Irina O. Chikileva, Tatiana N. Abashina, Ashot M. Manoyan, Olga E. Ivanova, Tigran T. Papazyan, Ilia N. Nikonov, Nataliya E. Suzina, Vyacheslav G. Melnikov, Valentin S. Khlebnikov, Vadim K. Sakulin, Vladimir A. Samoilenko, Alexey B. Gordeev, Gennady T. Sukhikh, Vladimir N. Uversky, Andrey V. Karlyshev

“…The ability of the LC2029 and LS7247 consortium to promote intestinal homeostasis in vitro was assessed by the effectiveness of controlling CJ-induced TLR4 activation, secretion of pro-inflammatory cytokines, development of intestinal barrier dysfunction, and production of intestinal alkaline phosphatase (IAP). …”
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Neonatal hypoxia leads to impaired intestinal function and changes in the composition and metabolism of its microbiota by Jun Wen, Yue Wu, Fengfeng Zhang, Yanchu Wang, Aifen Yang, Wenwen Lu, Xiaofeng Zhao, Huaping Tao

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Patterns and Underlying Mechanisms of Airway Epithelial Cell Death in COPD by Ting Wang, Yuanji Dong, Liangjie Fang, Hua Zhou

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