Identification and functional characterization of cardiac pacemaker cells in zebrafish. by Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers

“…Here we show that zebrafish embryos lacking the LIM/homeodomain-containing transcription factor Isl1 display heart rate defects related to pacemaker dysfunction. Moreover, 3D reconstructions of gene expression patterns in the embryonic and adult zebrafish heart led us to uncover a previously unidentified, Isl1-positive and Tbx2b-positive region in the myocardium at the junction of the sinus venosus and atrium. …”
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Трансплантация суспензии эндотелиальных клеток в эксперименте ex vivo by B.E. Malyugin, S.A. Borzenok, O.P. Antonova, D.S. Ostrovskii, Z.R. Ebzeeva

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Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review by Quang La, Aiman Baloch, David F. Lo

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Targeting T cell exhaustion: emerging strategies in non-small cell lung cancer by Xianqiang Liu, Xianqiang Liu, Xiaowei Xi, Shengshan Xu, Hongyu Chu, Penghui Hu, Dong Li, Bin Zhang, Bin Zhang, Hejie Liu, Tianxiao Jiang, Zhuming Lu

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Inhibiting MARCH5/Mfn2 signaling as an alternative strategy to protect cardiomyocytes from hypoxia-induced mitochondrial dysfunction by Faten Habrat Zoabi, Mulate Zerihun, Roy Lizarovich, Chiara Dalla Torre, Liron Davis, Offir Ertracht, Michal Barsheshet, Shaul Atar, Deborah E. Shalev, Marta De Zotti, Hanoch Senderowitz, Nir Qvit

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Mitochondrial dysfunction in Gulf War illness revealed by 31Phosphorus Magnetic Resonance Spectroscopy: a case-control study. by Hayley J Koslik, Gavin Hamilton, Beatrice A Golomb

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Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction by Marta Camici, Giulia Del Duca, Anna Clelia Brita, Andrea Antinori

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IgA Dysfunction Induced by Early-Lifetime Low-Dose Antibiotics Exposure Aggravates Diet–Induced Metabolic Syndrome by Xue Han, Yue Qin, Jielong Guo, Weidong Huang, Yilin You, Jicheng Zhan, Yue Yin

“…These pathological changes exacerbated diet-induced MetS. <b>Discussion:</b> Our findings demonstrate that early-life LDP exposure induces persistent intestinal IgA deficiency through lasting GM alterations initiated in early development. …”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles: Emerging Therapies for Neurodegenerative Diseases by Chen P, Wang F, Ling B, Zhu Y, Lin H, Huang J, Wang X

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Personalized Nutrition for Obesity Management: A Mini-Review by Michael T. Okafor

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Understanding the impact of ER stress on lung physiology by Zhiling Fu, Wei Wang, Yuan Gao

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Single-cell transcriptomic analysis identifies a stress response Schwann cell subtype by Lan Xianfeng, Zheng Yanmei, You Yongliang, Wu Xuejun, Wu Shaojie, Chen Nengfu, Wang Lihong, Yang Wenfu

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Neurokinin 1 receptor inhibition alleviated mitochondrial dysfunction via restoring purine nucleotide cycle disorder driven by substance P in acute pancreatitis by Chenxia Han, Lu Li, Lin Bai, Yaling Wu, Jiawang Li, Yiqin Wang, Wanmeng Li, Xue Ren, Ping Liao, Xiaoting Chen, Yaguang Zhang, Fengzhi Wu, Feng Li, Dan Du, Qing Xia

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The Druggable Target Potential of NF-κB-Inducing Kinase (NIK) in Cancer by Yina Wang, Liangyou Rui

“…Emerging evidence suggests that dysregulated expression or function of NIK in non-lymphoid cells is a key factor in cancer progression. While NIK deficiency causes severe immune dysfunction, its overexpression or excessive activation is linked to inflammatory diseases, metabolic disorders, and cancer development. …”
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Inflammatory Cell Interactions in the Rotator Cuff Microenvironment: Insights From Single-Cell Sequencing by Wencai Liu, Xinyu Wang, Yuhao Yu, Weiming Lin, Hui Xu, Xiping Jiang, Chenrui Yuan, Yifei Wang, Xin Wang, Wei Song, Yaohua He

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CONTEMPORARY SIGHT AT AMLODIPINE AND NEW DRUGS OF S-AMLODIPINE by M. V. Leonova

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Lysosomal targeting of liposomes with acidic pH and Cathepsin B induces protein aggregate clearance by Minsol Jeon, Da-Eun Kim, So Young Choi, Seoyoung Kim, Seongchan Kim, Hyojin Lee, Hyunkyung Kim

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Emerging Mechanistic Insights and Therapeutic Strategies for Pulmonary Arterial Hypertension: A Focus on Right Ventricular Dysfunction and Novel Treatment Pathways by Masab Mansoor, Andrew F. Ibrahim

“…<b>Background/Objectives</b>: Pulmonary arterial hypertension (PAH) is a progressive vascular disorder characterized by increased pulmonary vascular resistance, right ventricular dysfunction, and high mortality rates. …”
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HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis by Runkuan Yang, Jyrki Tenhunen, Tor Inge Tonnessen

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ANALYSIS OF THE MODERN STATUS OF CLINICAL AND EXPERIMENTAL DATA ABOUT INTERACTION BETWEEN NERVOUS AND IMMUNE SYSTEMS by T. A. Nikiforova (Postnikova), S. A. Peskov, O. B. Doronina

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