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    Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. by Huan Yun, Liang Sun, Qingqing Wu, Geng Zong, Qibin Qi, Huaixing Li, He Zheng, Rong Zeng, Liming Liang, Xu Lin

    Published 2020-12-01
    “…Mediation analysis suggested that the detrimental associations of 13 sphingolipids with T2D were largely mediated through β-cell dysfunction, as indicated by HOMA-B (mediation proportion: 11.19%-42.42%; all P < 0.001). …”
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    Macrophage‐Hepatocyte Circuits Mediated by Grancalcin Aggravate the Progression of Metabolic Dysfunction Associated Steatohepatitis by Tian Su, Yue He, Min Wang, Haiyan Zhou, Yan Huang, Mingsheng Ye, Qi Guo, Ye Xiao, Guangping Cai, Mingyang Zhao, Jianping Wang, Xianghang Luo

    Published 2024-11-01
    “…Notably, the administration of recombinant GCA aggravates the development of MASH, whereas, Gca deletion in myeloid cells blunts liver steatosis and inflammation in multiple MASH murine models. …”
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    Punicic acid alleviates methylglyoxal-induced oocyte dysfunction during in vitro maturation in mouse species. by Shahrzad Ronasi, Amir Hossein Mahdavi, Shiva Rouhollahi Varnosfaderani, Rasoul Kowsar, Farnoosh Jafarpour, Mohammad Hossein Nasr-Esfahani

    Published 2025-01-01
    “…Lastly, PA supplementation improved cell lineage allocation in blastocysts developed from MGO-challenged oocytes, emphasizing its role in enhancing the quality of preimplantation embryos. …”
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    Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery by Wanli Ma, Xinyi Liu, Ran Yu, Jiannan Song, Lina Hou, Ying Guo, Hongwei Wu, Dandan Feng, Qi Zhou, Haibo Li

    Published 2025-02-01
    “…Immune infiltration analysis revealed significant differences in immune cell populations, mainly activated dendritic cells, and effector memory CD8+ T cells, between sepsis patients and healthy controls. …”
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