Diagnostic significance of TGF-β1 in kidney recipients with graft dysfunction by О. P. Shevchenko, S. О. Sharapchenko, D. A. Velikiy, О. Е. Gichkun, E. S. Stolyarevich, N. P. Mozheiko, D. A. Saydulaev, R. М. Kurabekova, E. A. Vakurova, A. A. Mamedova, M. A. Osoblivaya

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Aflatoxin-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus Disease by Yi Jiang, Pauline E. Jolly, Peter Preko, Jia-Sheng Wang, William O. Ellis, Timothy D. Phillips, Jonathan H. Williams

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Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

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Deep proteome profiling of metabolic dysfunction-associated steatotic liver disease by Felix Boel, Vyacheslav Akimov, Mathias Teuchler, Mike Krogh Terkelsen, Charlotte Wilhelmina Wernberg, Frederik Tibert Larsen, Philip Hallenborg, Mette Munk Lauridsen, Aleksander Krag, Susanne Mandrup, Kim Ravnskjær, Blagoy Blagoev

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Possibility of Using NO Modulators for Pharmacocorrection of Endothelial Dysfunction After Prenatal Hypoxia by Igor Belenichev, Olena Popazova, Oleh Yadlovskyi, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Valentyn Oksenych, Oleksandr Kamyshnyi

“…Prenatal hypoxia (PH) is a key factor in the development of long-term cardiovascular disorders, which are caused by various mechanisms of endothelial dysfunction (ED), including those associated with NO deficiency. …”
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Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway by Dan Lu, Linqi Liu, Wenjun Que, Rui Fan, Pingyang Ke, Jing Dong, Yaoqi Gan, Fei Xiao

“…While neuroendocrine-immune system dysfunction plays a crucial role in the development of autoimmune diseases, its involvement in MG remains largely unexplored. …”
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Organ dysfunction induced by hemorrhagic shock: From mechanisms to therapeutic medicines by Qingxia Huang, Yisa Wang, Zepeng Zhang, Mingxia Wu, Jiaqi Liu, Jinjin Chen, Jing Li, Yao Yao, Chen Guo, Daqing Zhao, Wenxiu Qi, Xiangyan Li

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LASER THERAPY FOR MANAGEMENT OF CEREBRAL DYSFUNCTION IN CASES OF ACUTE SEVERE PANCREATITIS by A. P. Vlasov, D. Y. Timoshkin, M. A. Spirina, I. A. Chigakova, T. I. Vlasova, T. A. Muratova

“…The severity of cerebral dysfunction was assessed within controlled terms with the help of RASS and psychometric tests: number connection tests (A and B), “Point in circle”, “Labyrinth”, test of symbols and numbers. …”
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CO43 | Early platelet dysfunction in sepsis: an ICU pilot study

“…Ex vivo platelet hyporeactivity likely reflects in vivo platelet exhaustion in sepsis patients as a consequence of direct activation of platelets by microorganisms and/or cytokines released by immune cells. Early detection of platelet dysfunction may help guide early interventions to prevent hemostatic imbalance and organ failure in septic patients.   …”
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BNSTGABA neurons regulate autophagy to alleviate depression with gastric dysfunction symptoms by Yi Yuan, Jiangang Xu, Shanlan Zhu, Hongkun Ma, Hao Wang, Xiyang Wang, Guoming Shen

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RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study by Nurul Iffah Mohd Isa, Aslah Nabilah Abdull Sukor, Saiful Effendi Syafruddin, Mohd Faizal Ahmad, Shahidee Zainal Abidin, Mohd Helmy Mokhtar, Azizah Ugusman, Azizah Ugusman, Adila A. Hamid, Adila A. Hamid

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Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. by Claudia P Cabrera, Joanna Manson, Joanna M Shepherd, Hew D Torrance, David Watson, M Paula Longhi, Mimoza Hoti, Minal B Patel, Michael O'Dwyer, Sussan Nourshargh, Daniel J Pennington, Michael R Barnes, Karim Brohi

“…Immune deconvolution, flow cytometry, and modular analysis suggested a central role for neutrophils and Natural Killer (NK) cells, with underexpression of T- and B cell responses. …”
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Developing a novel aging assessment model to uncover heterogeneity in organ aging and screening of aging-related drugs by Yingqi Xu, Maohao Li, Congxue Hu, Yawen Luo, Xing Gao, Xinyu Li, Xia Li, Yunpeng Zhang

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Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction by Cathrin E. Hansen, Davide Vacondio, Lennart van der Molen, Annika A. Jüttner, Wing Ka Fung, Manon Karsten, Bert van het Hof, Ruud D. Fontijn, Gijs Kooij, Maarten E. Witte, Anton J. M. Roks, Helga E. de Vries, Inge Mulder, Nienke M. de Wit

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Loss of dynamin 1-like protein impairs mitochondrial function and self-renewal, and activates the integrated stress response in human embryonic stem cells by Artur Cieslar-Pobuda, Artur Cieslar-Pobuda, Safak Caglayan, Safak Caglayan

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Mitochondrial stress disassembles nuclear architecture through proteolytic activation of PKCδ and Lamin B1 phosphorylation in neuronal cells: implications for pathogenesis of age-r... by Adhithiya Charli, Yuan-Teng Chang, Jie Luo, Bharathi Palanisamy, Emir Malovic, Zainab Riaz, Cameron Miller, Manikandan Samidurai, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy, Anumantha G. Kanthasamy

“…In silico analyses identified threonine site on Lamin B1 (T575) as a phosphorylation site of PKCδ. Interestingly, N27 DAergic cells stably expressing a PKCδ cleavage-resistant mutant failed to induce nuclear damage, PKCδ activation, and Lamin B1 phosphorylation. …”
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Mechanistic insights into the role of EGLN3 in pulmonary vascular remodeling and endothelial dysfunction by Xiaodong Deng, Qing Que, Kunchi Zhang, Bo Li, Nianlong Yang, Qiang Hu, Sheng Lv, Yi Liu

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Rescuing vascular dysfunction in dorsal pancreatic arteries prevents tacrolimus-induced glucose metabolism disorder in mice by Lingyan Fei, Honghong Wang, Dongliang Zhao, Xiaohua Wang, Jizhen Ren, Lanyun Liu, Chun Tang, Yan Lei, Qingqing Wang, Yuanpeng Nie, Yang Liu, Na Li, Ming Zhong, Nan Xu, Jin Wei, Pontus B. Persson, Andraes Patzak, Pratik H. Khedkar, Zhihua Zheng, Shan Jiang

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Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations by Wen Yih Aw, Aanya Sawhney, Mitesh Rathod, Chloe P. Whitworth, Elizabeth L. Doherty, Ethan Madden, Jingming Lu, Kaden Westphal, Ryan Stack, William J. Polacheck

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Sirtuins and Gut Microbiota: Dynamics in Health and a Journey from Metabolic Dysfunction to Hepatocellular Carcinoma by Mahmoud Zhra, Muhammad Affan Elahi, Aamira Tariq, Ahmed Abu-Zaid, Ahmed Yaqinuddin

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