Applicability and Validity of the “Bronchiectasis Severity Index” (BSI) and “FACED” Score in Adult Aboriginal Australians by Howarth T, Gibbs C, Abeyaratne A, Heraganahally SS

“…To date, it is unclear if these existing bronchiectasis assessment tools are appropriate or applicable for Indigenous people. Therefore, this study assessed how existing bronchiectasis tools, namely the “Bronchiectasis Severity Index” (BSI) and “FACED” [Forced expiratory volume in 1 s, Age, Chronic colonization, Extension, and Dyspnea] fit for an adult Indigenous/ Aboriginal Australian cohort diagnosed to have bronchiectasis. …”
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The combination of odontogenic stem cells and mandibular advancement promotes the length of the mandible in adult rats by facilitating the development of condylar cartilage by Xin Cheng, Liangching Huang, Huijuan Wang, SiLong Lei, Chichong Chan, Xuesong Yang, Yue Huang

“…There is a pressing need to explore innovative methods to promote the adaptive remodeling of adult condylar cartilage and the mandible in response to external stimuli. …”
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Polypharmacy or potentially inappropriate medications among older adults with COVID-19 in a secondary hospital in China and their association with mortality by Mian Mao, Shan Du, Yue Xu, Qiu Li, Ruoxi Luo, Qiaoqiao Zhou, Xiaoli Hu

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Processes of care and survival associated with treatment in specialist teenage and young adult cancer centres: results from the BRIGHTLIGHT cohort study by Stephen Morris, Rosalind Raine, Faith Gibson, Rachel M Taylor, Jeremy Whelan, Richard Feltbower, Lorna A Fern, Julie Barber, Javier Alvarez-Galvez, Louise Hooker, Dan P Stark, Ana Martins, Sarah Lea

“…We aimed to examine the association between exposure to TYA-PTC care, survival and documentation of clinical processes of care.Design Prospective cohort study.Setting 109 National Health Service (NHS) hospitals across England.Participants 1114 TYA, aged 13–24, newly diagnosed with cancer between 2012 and 2014.Intervention Participants were assigned a TYA-PTC category dependent on the proportion of care delivered in a TYA-PTC in the first year after diagnosis: all care in a TYA-PTC (ALL-TYA-PTC, n=270), no care in a TYA-PTC (NO-TYA-PTC, n=359), and some care in a TYA-PTC with additional care in a children’s/adult unit (SOME-TYA-PTC, n=419).Primary outcome Data were collected on documented processes indicative of age-appropriate care using clinical report forms, and survival through linkage to NHS databases.Results TYA receiving NO-TYA-PTC care were less likely to have documentation of molecular diagnosis, be reviewed by a children’s or TYA multidisciplinary team, be assessed by supportive care services or have a fertility discussion. …”
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Transition from child to adult health services for young people with cerebral palsy in Ireland: a mixed-methods study protocol by Meriel Norris, Jennifer M Ryan, Michael Walsh, Aisling Walsh, Thilo Kroll, M Byrne, Jennifer Fortune, Grace Lavelle, C Kerr, Owen Hensey, Mary Owens

“…Introduction The transition from child to adult health services is a challenging and complex process for young people with cerebral palsy (CP). …”
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CURRENT ISSUES AND OPTIONS FOR HORMONAL CONTRACEPTION IN ADOLESCENTS AND YOUNG ADULT WOMEN WITH SICKLE CELL DISEASE: AN UPDATE FOR HEALTH CARE PROFESSIONALS by Vincenzo De Sanctis

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Religiosity vs tobacco use: Religion’s impact on tobacco use among adult Indian population – A cross sectional study by Priyadharshini Ragavane, Shivashankar Kengadaran

“…Methods: A Descriptive cross-sectional study was conducted among 174 adult subjects of smoking and smokeless tobacco users. …”
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scRNA-seq revealed transcriptional signatures of human umbilical cord primitive stem cells and their germ lineage origin regulated by imprinted genes by Justyna Jarczak, Kamila Bujko, Mariusz Z. Ratajczak, Magdalena Kucia

“…Molecular analysis of adult murine BM-purified VSELs revealed that these rare cells deposited during development in adult tissues (i) express a similar transcriptome as embryonic stem cells, (ii) share several markers characteristic for epiblast and migratory primordial germ cells (PGCs), (iii) highly express a polycomb group protein enhancer of zeste drosophila homolog 2 (Ezh2) and finally (iv) display a unique pattern of imprinting at crucial paternally inherited genes that promotes their quiescence. …”
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Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital— by Yasuhiro Ito, Akira Miyauchi, Makoto Fujishima, Masashi Yamamoto, Takahiro Sasaki

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The geriatrics research instrument library: A resource for guiding instrument selection for researchers studying older adults with multiple chronic conditions by Mayra Tisminetzky, Christopher Delude, Heather G Allore, Kathryn Anzuoni, Sarah Bloomstone, Peter Charpentier, John P Hepler, Dalane W Kitzman, Gail J McAvay, Michael Miller, Nicholas M Pajewski, Jerry Gurwitz

“…Conclusions GRIL provides a user-friendly public resource that facilitates clinical researchers in efficiently selecting appropriate instruments to measure clinical outcomes relevant to older adults across a full range of domains.…”
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Dyslipidemia and Development of Chronic Kidney Disease in Non-Diabetic Japanese Adults: A 26-Year, Community-Based, Longitudinal Study by Yukari Okawa, Toshiharu Mitsuhashi

“…This longitudinal study (1998–2024) examined whether the prevalence of dyslipidemia is associated with the subsequent development of CKD in non-diabetic Japanese adult citizens of Zentsuji, Kagawa Prefecture, Japan. …”
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Dizziness and unstable gait in the older adults are associated with vestibular hypofunction, muscle dysfunction and sleep disturbance: impact on prevention of accidental falls by Katsuhisa Ikeda, Kumiko Tanaka, Shori Tajima, Tomokazu Takakura, Masami Sugihara, Koichi Ono

“…In addition, vitamin B1 and B12 deficiency, and cognitive and visual impairment secondarily contribute to dizziness and unstable gait. Appropriate selection of treatment according to the underlying causes would prevent accidental falls among the older adults.…”
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Rapid review: Ten ways to improve support for minoritised informal adult carers at local government policy level to redress inequality by A. Barnes, F. Phillips, K. Pickett, A.J. Haider, J. Robinson-Joyce, S. Ahmed

“…Objective: To rapidly identify and summarise evidence on key factors that affect access to support for minoritised informal adult carers which could be addressed at the level of local government policy-making. …”
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Pharmacokinetic/pharmacodynamic analysis of tedizolid phosphate against Staphylococcus aureus and Streptococcus pneumoniae in children, adolescents, and adults by Monte Carlo simul... by Xiao-Chen Wei, Ming-Feng Zhao, Hai-Rong Lv, Xia Xiao

“…Conclusions: These pharmacokinetics/pharmacodynamics-based simulations rationalize and optimize the dosage regimens of tedizolid phosphate against S. aureus and S. pneumoniae in children, adolescents, and adults.…”
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Feasibility of engaging parents attending an adult weight management programme with child weight management support: a mixed methods study by Russell Jago, Julian PH Shield, Aidan Searle, Ruth Mears, Deborah Sharp

“…Objective To explore whether parents’ attendance at a commercial adult weight management programme (WMP) offers an opportunity to identify and signpost families to child weight management support, if appropriate to a child’s weight status.Design Mixed methods study including a cross-sectional online survey and semistructured telephone interviews.Setting and participants Parents attending Slimming World (UK-based adult commercial WMP), with one or more children aged 5–11 years, were invited to take part. …”
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Association between Atherogenic index of plasma and gallstones in the United States adults: A cross-sectional analysis of NHANES 2017–2020 by Shuang Yang, Jianhui Song, Zhengbo Yang, Nanbo Li, Ju Wu, Shuangshuang Hou

“…Methods: A total of 3557 eligible adults from the United States were selected for cross-sectional analysis using the 2017–2020 National Health and Nutrition Examination Survey database. …”
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Association of dietary anthocyanidins intake with all-cause mortality and cardiovascular diseases mortality in USA adults: a prospective cohort study by Yifei Yan, Jianchang Li

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Mapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review by Yuanyuan Zhao, Boon How Chew, Yuehua Tu, Eva Marie Gacasan

“…However, there is a lack of sufficient evidence on practices in such facilities, particularly for Chinese older adults. The aim of this scoping review is to map the existing literature and inform the development of an appropriate care framework for end-of-life care in nursing homes. …”
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Longitudinal trends and predictors of limitations in activities of daily living in community-dwelling older adults: evidence from the KLoSA study by Eunmi Oh, SeolHwa Moon, Gwi-Ryung Son Hong

“…In particular, because age and cognitive function were identified as the major predictors for limitations in both total ADLs and the top three ADLs, early assessment and appropriate intervention strategies need to consider those factors to prevent ADL limitations in older adults or to meet the immediate needs of those already experiencing ADL limitations. …”
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Public Awareness Levels Regarding Cervical Spine Injury and the Suitable First Aid Response Among Adults in Makkah, Saudi Arabia by Alghamdi FA, Alghamdi GA, Almatrafi WS, Alghamdi RF, Kelantan SR, Abdulsamad FF, Bawahab NS, Babateen O, Albar HT, Hariri NH

“…Educating the public about these injuries and appropriate emergency responses is crucial to prevent irreversible damage, minimize disability, and save lives, especially with the rising number of trauma victims worldwide. …”
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