Asini Corii Colla (Ejiao) as a health-care food and traditional Chinese medicine: A review of its chemical composition, pharmacological activity, quality control, modern applicatio... by Xiao-jun Yu, Ling-mei Kong, Bin Wang, Chang-qi Zhai, Yong-zhen Lao, Long-jian Zhang, Yan Gao, Bo-Nian Zhao

“…It is rich in protein, polypeptides, amino acids, fatty acids, polysaccharides, and other components. …”
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Soil organic matter composition affects ecosystem multifunctionality by mediating the composition of microbial communities in long-term restored meadows by Wenyin Wang, Sisi Bi, Fei Li, A. Allan Degen, Shanshan Li, Mei Huang, Binyu Luo, Tao Zhang, Shuai Qi, Tianyun Qi, Yanfu Bai, Peipei Liu, Zhanhuan Shang

“…Carbon metabolism did not increase in restored meadows, but the niche breadth of soil microorganisms and the utilization efficiency of small molecular carbon sources such as amino acids did increase. Conclusions These findings emphasize the importance of soil organic matter composition in ecological restoration and that the composition should be considered in management strategies aimed at enhancing EMF.…”
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Antioxidant and Anti-Inflammatory Potential of Cymbopogon nardus Ethanol Extract on 3T3-L1 Cells by Rohmawaty E, Wiraswati HL, Zahra TA, Amalina SN, Ramadhanti J, Rosdianto AM, Laelalugina A, Nasution GTD, Kamisah Y

“…Enny Rohmawaty,1 Hesti Lina Wiraswati,1 Tamara Aliya Zahra,2 Shabrina Nur Amalina,2 Julia Ramadhanti,1 Aziiz Mardanarian Rosdianto,1 Amila Laelalugina,3 Gita Tiara Dewi Nasution,1 Yusof Kamisah4 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, 40161, Indonesia; 2Undergraduate Program Medical Doctor, Faculty of Medicine, Universitas Padjadjaran, Bandung, 40161, Indonesia; 3Oncology and Stem Cell Working Group, Universitas Padjadjaran, Bandung, 40161, Indonesia; 4Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 53000, MalaysiaCorrespondence: Enny Rohmawaty, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jl. …”
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Differences in Metabolites of Different Varieties from Xinjiang Large-fruit Sea Buckthorn as Analyzed by Non-targeted Metabolomics by Rong HAN, Yan MA, Shengjie LI, Xintao MENG, Mingqiang XU, Ting ZHANG, Yan PAN

“…Based on the VIP value>1, log2FC absolute value≥1 and FDR<0.05 screening criteria, a total of five differential metabolites were found, and overall high abundance and lipid-like molecules, phenylpropanes and polyketides were found in sea buckthorn, ranging from 38% to 81% and 15% to 49%, respectively, among which erucic acid amide, linoleic acid, palmitic acid, narcissin, isorhamnetin-3-O-glucoside, rutin, etc. might be the key metabolites to identify different Xinjiang large-fruit sea buckthorn. …”
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Lead toxicity in Nicotiana tabacum L.: Damage antioxidant system and disturb plant metabolism by Tengfei Liu, Kai Zhang, Chunlan Ming, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiewang He, Fengfeng Liu, Yinghui Zhou, Jiayang Xu, Mohamed G. Moussa, Shenghua Zhang, Wei Jia

“…These results indicate that increasing the content of photosynthetic pigments and hormones, clearing reactive oxygen species by enhancing antioxidant enzyme activity, and improving amino acid metabolism may play an important role in reducing the toxicity of Pb to tobacco.…”
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Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…We noticed that biochemical and pathological changes corresponded to the infrared (IR) peaks at 1545 cm-1 and 1511 cm-1 (amide II), 1246 cm-1 (DNA/RNA phosphate backbones), and 1181 cm-1 (C–O vibrations). …”
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Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

“…A new mutation in the domain V region of 23S rRNA gene (C2404T) and one mutation in amino acid sequences of ribosomal protein (Met208Thr) were firstly identified among linezolid-resistant strains. …”
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Role of Fcγ receptors in HER2-targeted breast cancer therapy by Hope S Rugo, Antonino Musolino, William J Gradishar, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

“…An example of an approved anti-HER2 Fc-engineered chimeric mAb is margetuximab, which targets the same epitope as trastuzumab, but features five amino acid substitutions in the IgG 1 Fc domain that were deliberately introduced to increase binding to activating FcγRIIIa and decrease binding to inhibitory FcγRIIb (CD32B). …”
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Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics by Xiao Ma, Tengda Huang, Xiangzheng Chen, Qian Li, Mingheng Liao, Li Fu, Jiwei Huang, Kefei Yuan, Zhen Wang, Yong Zeng

“…Viewed through the lens of metabolic reprogramming, these pathways highlight how shifts in glucose, lipid, and amino acid metabolism support the cellular functions essential for liver repair and regeneration. …”
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Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

“…It also downregulated mGluR5 and modulated the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits: GluA1 was downregulated, inhibiting long-term potentiation, while GluA2 and GluA3 were upregulated in the nigrostriatal pathway in PD animal models. …”
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ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism by Christoffer Löf, Nasrin Sultana, Neha Goel, Samuel Heron, Gudrun Wahlström, Andrew House, Minna Holopainen, Reijo Käkelä, Johanna Schleutker

“…Targeted metabolomics showed reduced levels of the amino acid aspartate, indicating disrupted mitochondrial function in the ANO7-expressing cells. …”
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Preliminary analysis of the role of small hepatitis B surface proteins mutations in the pathogenesis of occult hepatitis B infection via the endoplasmic reticulum stress-induced UP... by Huang Chengrong, Zhang Hao, Wang Jing, Li Jianfei, Liu Qian, Zong Qiyin, Zhang Yunyun, Wang Qin, Zhou Qiang

“…A growing body of evidence has shown that hepatitis B surface antigen (HBsAg) mutations can influence the occurrence of occult hepatitis B infection (OBI), particularly amino acid substitutions in small hepatitis B surface proteins (SHBs). …”
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A novel platform for engineered AAV-based vaccines by Sabrina Babutzka, Miranda Gehrke, Anastasia Papadopoulou, Maria Diedrichs-Möhring, Maria Giannaki, Lena Hennis, Bastian Föhr, Cale Kooyman, Andreas Osterman, Evangelia Yannaki, Gerhild Wildner, Hermann Ammer, Stylianos Michalakis

“…Using SARS-CoV-2 as a model pathogen, we introduced ∼200 amino acids of the SARS-CoV-2 receptor-binding domain (RBD) into a surface-exposed variable loop region of AAV2 and AAV9, resulting in AAV2.RBD and AAV9.RBD capsids (AAV.RBDs). …”
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Integration of metabolomic and transcriptomic analyses reveals regulatory functions of the ChREBP transcription factor in energy metabolism by Jie An, Inna Astapova, Guofang Zhang, Andrew L. Cangelosi, Olga Ilkayeva, Hannah Marchuk, Michael J. Muehlbauer, Tabitha George, Joseph Brozinick, Mark A. Herman, Christopher B. Newgard

“…Despite suppression of pyruvate kinase, pyruvate levels are maintained, possibly via increased expression of pyruvate and amino acid transporters. In addition, expression of multiple anaplerotic enzymes is decreased by GalNac-siChREBP treatment, affecting TCA cycle intermediates. …”
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Wet pulverization combined with temperature cycling strategy for extraction of Stropharia rugosoannulata protein with attenuating hepatic steatosis on obese mice by Peng Liu, Chen Gao, Wen Li, Wanchao Chen, Zhong Zhang, Di Wu, Tingzhao Li, Shuai Sun, Yan Yang

“…Herein, S. rugosoannulata protein (SRA) with mainly molecular weight of 15, 40 and 50 kDa, complete amino acid composition and typical α-helix structure, was obtained by wet pulverization combined with temperature cycling strategy. …”
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Metabolites and lipid species mediate the associations of adiposity in childhood and early adulthood with mammographic breast density in premenopausal women by Kayla R. Getz, Myung Sik Jeon, Lili Liu, Lei Liu, Haixiang Zhang, Chongliang Luo, Jingqin Luo, Adetunji T. Toriola

“…Conclusions Metabolites in amino acid, lipid, cofactor/vitamin, and xenobiotic super-pathways as well as lipid species across the phospholipid, neutral complex lipid and sphingolipid super-pathways mediated the associations of BMI in early-life and MBD in premenopausal women. …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…These could be seen as how art exhibitions and institutions, the encouragement of certain art-production through predominantly featured picturesque and peaceful landscapes, and portrayals that create a sense of calm and tranquillity amidst the violent climate of the Malayan Emergency were intended to alleviate anxieties and provide solace to the public. …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…These could be seen as how art exhibitions and institutions, the encouragement of certain art-production through predominantly featured picturesque and peaceful landscapes, and portrayals that create a sense of calm and tranquillity amidst the violent climate of the Malayan Emergency were intended to alleviate anxieties and provide solace to the public. …”
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Elucidating the degradation mechanism of beef myofibrillar proteins under hydroxyl radical oxidation through the lens of cysteine oxidation modifications by Jiale Li, Jun Liu, Hui Yue, Yuanyuan Ma, He Li, Yuanliang Hu, Xiang Yu, Weiwei Dong, Yanli Feng

“…The Cys of actin (17 Dos), myosin/myomesin (16 Dos), tenascin (12 Dos) and sarcomere (10 Dos) in the MPs structure showed active oxidative modification behavior towards ·OH, especially with the “-C-X-X-X-X-W-” structure amino acid sequence showed high sensitivity. Notably, the oxidative modification of Cys by ·OH was an irreversible process, as evidenced mainly by a significant decrease (p < 0.05) in protein sulfhydryl groups and unfolding of protein secondary and tertiary structures. …”
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