Intersection of rare pathogenic variants from TCGA in the All of Us Research Program v6 by Blaine A. Bates, Kylee E. Bates, Spencer A. Boris, Colin Wessman, David Stone, Justin Bryan, Mary F. Davis, Matthew H. Bailey

“…Summary: Using rare cancer predisposition alleles derived from The Cancer Genome Atlas (TCGA) and high cancer prevalence (14% of participants) in All of Us (version 6), we assessed the impact of these rare alleles on cancer occurrence in six broad groups of genetic similarity provided by All of Us: African/African American (AFR), Admixed American/Latino (AMR), East Asian (EAS), European (EUR), Middle Eastern (MID), or South Asian (SAS). …”
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Association between Metformin Use and Cancer Stage at Diagnosis among Elderly Medicare Beneficiaries with Preexisting Type 2 Diabetes Mellitus and Incident Prostate Cancer by Amit D. Raval, Malcolm D. Mattes, Suresh Madhavan, Xiaoyun Pan, Wenhui Wei, Usha Sambamoorthi

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The Frequency of <i>DPYD</i> c.557A>G in the Dominican Population and Its Association with African Ancestry by Mariela Guevara, Carla González de la Cruz, Fernanda Rodrigues-Soares, Ernesto Rodríguez, Caíque Manóchio, Eva Peñas-Lledó, Pedro Dorado, Adrián LLerena

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Pilot study: Initial investigation suggests differences in EMT-associated gene expression in breast tumor regions by Kylie L. King, Hamed Abdollahi, Zoe Dinkel, Alannah Akins, Homayoun Valafar, Heather Dunn

“…The development of breast cancer is highly associated with interactions between tumor cells and the extracellular matrix (ECM), and recent research suggests that cellular components of the ECM vary between racial groups. …”
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Risk and Prognosis of Hepatocellular Carcinoma in Mexican Americans with Type 2 Diabetes Mellitus by Hatia RI, Hwang LY, Li R, Troisi C, Jalal PK, Amos CI, Gomez HF, Chun YS, Rashid A, Kaseb AO, Scheet PA, Hassan MM

“…Compared with patients who had DM for 2– 10 years, those who had it for at least 20 years had an AOR of 4.60 (P = 0.04). Metformin use was associated with a reduced risk of death in HCC cases with type 2 DM, with a hazard ratio of 0.72 (P = 0.01) as compared with non-users.Conclusion: Our results demonstrate that type 2 DM was independently associated with increased risk of HCC among Mexican Americans. …”
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Recognition and Treatment of BCG Failure in Bladder Cancer by Andrew J. Lightfoot, Henry M. Rosevear, Michael A. O'Donnell

“…Thus, both the American Urological Association and European Association of Urology recommend initial intravesical treatment with bacillus Calmette-Guerin(BCG) followed by maintenance therapy for a minimum of 1 year. …”
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Hartmann’s Procedure Versus Intersphincteric Abdominoperineal Excision in Patients with Rectal Cancer: Report from the Swedish Colorectal Cancer Registry (SCRCR) by Viktor Åkerlund, MD, Maziar Nikberg, MD, PhD, Philippe Wagner, PhD, Abbas Chabok, MD, PhD

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Global disparities in cancer supportive care: An international survey by Alexandre Chan, Lawson Eng, Changchuan Jiang, Mary Dagsi, Yu Ke, Mary Tanay, Cristiane Bergerot, Niharika Dixit, Ana Cardeña Gutiérrez, Ana I. Velazquez, Farhad Islami, Enrique Soto‐Perez‐de‐Celis

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Association of intratumoral microbiome diversity with hepatocellular carcinoma prognosis by Fengle Jiang, Yuan Dang, Zheting Zhang, Yanan Yan, Yingchao Wang, Yi Chen, Lihong Chen, Jialiang Zhang, Jingfeng Liu, Jianmin Wang

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The association between oral microbiome and gastric precancerous lesions by Yifei Chen, Lei Lei, Mengying Xia, Ran Cheng, He Cai, Tao Hu

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Helicobacter pylori and Biliary Tract Cancers: A Meta-Analysis by Soumia Cherif, Kaoutar Bouriat, Hanane Rais, Said Elantri, Abdessamad Amine

“…Epidemiological data on Helicobacter pylori infection and biliary tract cancer have been contradictory. Aim. The aim of this study is to explore and evaluate the association between the Helicobacter pylori infection and biliary tract cancer. …”
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Immunotherapeutic Potential of Lactobacillus Species as Immune Checkpoint Inhibitors in Cancer Immunotherapy by Renukadevi J, Sam Helinto J, Prena D

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Tumor Deposits as an Adverse Prognostic Indicator in Stage III Colon Cancer: A Multicenter Database Study by Jeeyou Kim, MD, Dong Woon Lee, MD, Ji Won Park, MD, PhD, Seung-Bum Ryoo, MD, PhD, Heung-Kwon Oh, MD, PhD, Rumi Shin, MD, PhD, Jin Sun Choi, MD, Min Jung Kim, MD, Sung-Chan Park, MD, Duck-Woo Kim, MD, PhD, Seung Chul Heo, MD, PhD, Sung-Bum Kang, MD, PhD, Seung-Yong Jeong, MD, PhD, Kyu Joo Park, MD, PhD, Jae Hwan Oh, MD, PhD, On Behalf of the Seoul Colorectal Research Group (SECOG)

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Crosstalk between Gut Microbiota and Cancer Immunotherapy: Present Investigations and Future Perspective by Yuhui Tang, Qiaoting Cai, Zhi Tian, Wenkuan Chen, Hailin Tang

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Search for clinical, genetic, morphological and immunohistochemical predictors of parathyroid cancer recurrence by Ekaterina I. Kim, Anna K. Eremkina, Alina R. Elfimova, Natalia G. Mokrysheva

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Risk of Colorectal Cancer in Ulcerative Colitis Patients: A Systematic Review and Meta-Analysis by Qing Zhou, Zhao-Feng Shen, Ben-sheng Wu, Cheng-biao Xu, Zhong-qi He, Tuo Chen, Hong-tao Shang, Chao-fan Xie, Si-yi Huang, Yu-gen Chen, Hai-bo Chen, Shu-tang Han

“…North American UC-associated CRC patients significantly increased in more than 30 years of this disease duration. …”
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Clinicopathological Factors Influencing Lymph Node Yield in Colorectal Cancer: A Retrospective Study by Elena Orsenigo, Giulia Gasparini, Michele Carlucci

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Survival and risk factors for metastatic colorectal cancer patients with a history of prior malignancy by Yiwen Qiu, Nida Cao, Dan Meng, Jian Yuan, Yingjie Zhu

“…Patients diagnosed with stage IV mCRC (per the American Joint Committee on Cancer [AJCC] 6th edition) between 2004 and 2015 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. …”
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CRYβB2 alters cell adhesion to promote invasion in a triple-negative breast cancer cell line by Amr A. Waly, London Harper, Jodie M. Fleming, Lindsey M. Costantini

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Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA) by Wei Zhao, Lisha Lin, Kristen M. Kelly, Lauren A. Opsasnick, Belinda L. Needham, Yongmei Liu, Srijan Sen, Jennifer A. Smith

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