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Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development
Published 2015-12-01“…Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease. …”
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122
Developing multifactorial dementia prediction models using clinical variables from cohorts in the US and Australia
Published 2025-01-01“…This study used machine learning to re-examine the diagnostic potential of clinical measures for dementia. Data was sourced from the Australian Imaging, Biomarkers, and Lifestyle Flagship Study of Ageing (AIBL) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). …”
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123
Classifying Dementia Using Local Binary Patterns from Different Regions in Magnetic Resonance Images
Published 2015-01-01“…We explored the use of 2D local binary pattern (LBP) extracted from FLAIR and T1 MR images of the brain combined with a Random Forest classifier in an attempt to discern patients with Alzheimer's disease (AD), Lewy body dementia (LBD), and normal controls (NC). …”
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124
The Diagnostic Role of Serum Inflammatory and Soluble Proteins on Dementia Subtypes: Correlation with Cognitive and Functional Decline
Published 2007-01-01“…However there are restricted data about the profile of the inflammatory and soluble proteins in well evaluated Alzheimer’s disease (AD), vascular dementia (VD), mild cognitive impairment (MCI) and healthy controls. …”
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ML-Based Quantitative Analysis of Linguistic and Speech Features Relevant in Predicting Alzheimer’s Disease
Published 2024-06-01“…Alzheimer’s disease (AD) is a severe neurological condition that affects numerous people globally with detrimental consequences. …”
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128
Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease
Published 2015-01-01“…Recent research has provided evidence that insulin resistance and impaired insulin signalling may be a contributory factor to the progression of diabetes, dementia, and other neurological disorders. Alzheimer’s disease (AD) is the most common subtype of dementia. …”
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129
COMPARISON OF COGNITIVE FUNCTION AND DEPRESSIVE SYMPTOMS IN INSTITUTIONALIZED HEALTHY AND OLDER PERSON WITH ALZHEIMER’S DISEASE
Published 2024-09-01“…Results show that active older person had higher scores in cognitive abilities (p = .001) and a lower incidence of depression (p = .001). It seems that Alzheimer’s disease, typically associated with cognitive abilities decline and incidence of depressive symptoms, and physical activity influence cognitive performance and depressive symptoms in older people with Alzheimer’s disease and without dementia. …”
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130
Modeling Alzheimer’s Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
Published 2016-01-01“…Alzheimer’s disease (AD) is the most prevalent type of dementia and its pathology is characterized by deposition of extracellular β-amyloid plaques, intracellular neurofibrillary tangles, and extensive neuron loss. …”
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131
Informed consent in dementia research: how Public Involvement can contribute to addressing “old” and “new” challenges
Published 2025-02-01“…This paper provides an overview of the perspectives of people with dementia and their carers resulting from Public Involvement activities organized by Alzheimer Europe. …”
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132
Transforming Alzheimer’s Disease Diagnosis: Implementing Vision Transformer (ViT) for MRI Images Classification
Published 2025-01-01“… Alzheimer’s disease (AD) is a progressive neurological disorder and the leading cause of dementia, accounting for 60-80% of cases. …”
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133
Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer’s Disease: A Metabolomic and Proteomic Approach
Published 2025-01-01“…Alzheimer’s disease (AD) is the leading cause of dementia among the elderly, yet effective treatments remain elusive. …”
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Assessing the Impact of Physical Activity on Dementia Progression Using Clustering and the MRI-Based Kullback–Leibler Divergence
Published 2025-01-01“…Dementia, including Alzheimer’s disease, is a neurodegenerative illness characterized by the progressive impairment of cognitive functions, posing a significant global health threat. …”
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135
Mitochondrial- and Endoplasmic Reticulum-Associated Oxidative Stress in Alzheimer's Disease: From Pathogenesis to Biomarkers
Published 2012-01-01“…Alzheimer's disease (AD) is the most common cause of dementia in the elderly, affecting several million of people worldwide. …”
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136
Klasifikasi Alzheimer Berdasarkan Data Citra MRI Otak Menggunakan Fcm Dan Anfis
Published 2023-07-01“…About 50 million people worldwide have Alzheimer's disease or another kind of dementia. Given many Alzheimer's patients, it is essential to identify it using brain MRI imaging. …”
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137
Intertwined depressive and cognitive trajectories and the risk of dementia and death in older adults: a competing risk analysis
Published 2024-04-01“…To date, their joint trajectories and associations with dementia and death remain underexplored.Aims To explore the interactions between depressive symptoms and cognitive function, their developmental trajectories and the associations with all-cause dementia, Alzheimer’s disease (AD) and all-cause death in older adults.Methods Data were from the Health and Retirement Study. …”
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Short-term variability of Alzheimer’s disease plasma biomarkers in a mixed memory clinic cohort
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139
Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease
Published 2011-01-01“…This study examined whether there were neuroanatomical differences evident on CT scans of individuals with dementia who differed on depression history. Neuroanatomical variables consisted of visual ratings of frontal lobe deep white matter, subcortical white matter, and subcortical gray matter hypodensities in the CT scans of 182 individuals from the Study of Dementia in Swedish Twins who were diagnosed with dementia and had information on depression history. …”
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Machine Learning Model-Based Applications for Food Management in Alzheimer’s Using Regression Analysis Approach
Published 2022-01-01“…Alzheimer’s disease (AD) has become a public health concern due to its misinterpretation with vascular dementia (VD) and mixed dementia Alzheimer’s disease (MXD). …”
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