Clinical Correlates of Awareness for Balance, Function, and Memory: Evidence for the Modality Specificity of Awareness by Megan E. O'Connell, Vanina Dal Bello-Haas, Margaret Crossley, Debra Morgan

“…Awareness of function was higher for participants with mild cognitive impairment (aMCI and non-aMCI) than for those with dementia (due to Alzheimer disease; AD and non-AD), whereas awareness of memory was higher for both non-aMCI and non-AD dementia patients than for those with aMCI or AD. …”
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Valproic Acid-Induced Myoclonus in a Demented Patient: A Case Report by Tina M. Gardner, Rehan Aziz, Sunanda Muralee, Rajesh R. Tampi

“…In this report, we describe the case of a 66-year-old woman with early-onset, Alzheimer's type dementia, who developed myoclonus when treated with a valproic acid preparation for behavioral disturbances associated with the dementia.…”
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Inflammatory biomarkers profiles and cognition among older adults by Aline Thomas, Jing Guo, Dolly Reyes-Dumeyer, Danurys Sanchez, Nikolaos Scarmeas, Jennifer J. Manly, Adam M. Brickman, Rafael A. Lantigua, Richard Mayeux, Yian Gu

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Effect of Combined Antihypertensive and Lipid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? by Ze-Min Kuang

“…Actively controlling potential risk factors from middle age may be important for Alzheimer’s disease (AD) prevention.…”
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Specificity of Cognitive Impairment in Neurological Disease: A Methodological Critique of Parkinson’s Disease by H. J. Sagar

“…Multiple cognitive deficits have been recognized in many neurological disorders but the specificity of the findings and the relationship to the underlying neuropathology remain obscure. Definitions of dementia have been proposed based on symptom profiles of the cognitive disorder and qualitative differences have been claimed between dementias of different aetiology. …”
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Association between osteoarthritis and cognitive function: results from the NHANES 2011–2014 and Mendelian randomization study by Kun Zhao, Liuyan Nie, Jingting Zhao, Yankai Dong, Kaixiu Jin, Song Wang, Xiangming Ye

“…Genetically predicted specific-site OA was not significantly associated with the risk of dementia (OR = 1.12; 95% CI: 0.96–1.32; p = 0.16), Alzheimer’s disease (OR = 0.95, 95% CI: 0.68–1.31, p = 0.74), vascular dementia (OR = 1.32, 95% CI: 0.82–2.13, p = 0.25) with accepted heterogeneity and no evidence of directional pleiotropy. …”
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Splicing accuracy varies across human introns, tissues, age and disease by S. García-Ruiz, D. Zhang, E. K. Gustavsson, G. Rocamora-Perez, M. Grant-Peters, A. Fairbrother-Browne, R. H. Reynolds, J. W. Brenton, A. L. Gil-Martínez, Z. Chen, D. C. Rio, J. A. Botia, S. Guelfi, L. Collado-Torres, M. Ryten

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White matter hyperintensities and cholinergic degeneration as Lewy body disease by Sungwoo Kang, Seun Jeon, Yeoju Kim, Su‐Hee Jeon, Minsun Choi, Young‐gun Lee, Mijin Yun, Byoung Seok Ye

“…Abstract Objective Although basal forebrain (BF) cholinergic degeneration and white matter hyperintensities (WMHs) are important in neurodegeneration in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), their relationships with dopaminergic degeneration and clinical manifestations remain unclear. …”
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Development and validation of the Michigan Chronic Disease Simulation Model (MICROSIM). by James F Burke, Luciana L Copeland, Jeremy B Sussman, Rodney A Hayward, Alden L Gross, Emily M Briceño, Rachael Whitney, Bruno J Giordani, Mitchell S V Elkind, Jennifer J Manly, Rebecca F Gottesman, Darrell J Gaskin, Stephen Sidney, Kristine Yaffe, Ralph L Sacco, Susan R Heckbert, Timothy M Hughes, Andrzej T Galecki, Deborah A Levine

“…Strategies to prevent or delay Alzheimer's disease and related dementias (AD/ADRD) are urgently needed, and blood pressure (BP) management is a promising strategy. …”
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Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes by Masafumi Ihara, Hidekazu Tomimoto

“…Vascular cognitive impairment is the second most common type of dementia after Alzheimer's disease and is frequently responsible for the cognitive decline of the elderly. …”
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Creutzfeldt-Jakob Disease as a Cause of Cognitive Decline and Seizures in the Elderly: Diagnostic Pointers and Strategy for Investigation by R. Williams, F. Cresswell, M. McClure, R. Lane

“…There is often a paucity of clues as to the underlying pathology, and while the diagnosis will usually prove to be either Alzheimer’s disease or vascular dementia, there may be clinical features suggesting rarer alternatives. …”
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The Tree-Drawing Test (Koch’s Baum Test): A Useful Aid to Diagnose Cognitive Impairment by Michelangelo Stanzani Maserati, Corrado Matacena, Luisa Sambati, Federico Oppi, Roberto Poda, Maddalena De Matteis, Roberto Gallassi

“…Consecutive outpatients were classified as affected by dementia (Alzheimer’s disease (AD), frontotemporal dementia (FTD), and vascular dementia (VD)) or by MCI. …”
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Acquired Localized Hypertrichosis Induced by Rivastigmine by Adrian Imbernón-Moya, Sebastian Podlipnik, Fernando Burgos, Elena Vargas-Laguna, Antonio Aguilar-Martínez, Eva Fernández-Cogolludo, Miguel Angel Gallego-Valdes

“…Rivastigmine is a reversible and competitive inhibitor of acetylcholinesterase and butyrylcholinesterase used for symptomatic treatment of Alzheimer dementia and Parkinson’s disease. It has an adequate safety profile and cutaneous side effects are unusual. …”
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An Approach to Diagnostic Criteria for the Definition of Slight Cognitive Impairment by Julio Armas Castro, Mayra Rosa Carrasco García, Sussette Angell Valdés, Yanet López Mena

“…For years the term slight cognitive impairment has been used in literature as a transitional stage between normal aging and a slight Alzheimer’s disease and in conversion studies it has been associated to quantitative and qualitative alterations that support that support the hypothesis that slight cognitive impairment constitutes an early stage of dementia in most of the patients. …”
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Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration by Camille Green, Vandana Zaman, Kayce Blumenstock, Narendra L. Banik, Azizul Haque

“…Furthermore, we review the potential links between these conditions and neuroinflammation and the development of neurodegenerative diseases like dementia, specifically Parkinson’s disease and Alzheimer’s disease.…”
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An MR Brain Images Classifier System via Particle Swarm Optimization and Kernel Support Vector Machine by Yudong Zhang, Shuihua Wang, Genlin Ji, Zhengchao Dong

“…The abnormal brain MR images consist of the following diseases: glioma, metastatic adenocarcinoma, metastatic bronchogenic carcinoma, meningioma, sarcoma, Alzheimer, Huntington, motor neuron disease, cerebral calcinosis, Pick’s disease, Alzheimer plus visual agnosia, multiple sclerosis, AIDS dementia, Lyme encephalopathy, herpes encephalitis, Creutzfeld-Jakob disease, and cerebral toxoplasmosis. …”
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Non-motor Disorders and their Neuro-anatomical Substrate in Parkinson's Disease by Julio López Argüelles, Leydi María Sosa Águila

“…Parkinson's disease remains the second most common degenerative disorder of the central nervous system after Alzheimer's. Although it was initially described as a condition with an exclusive motor disorder, it has been shown that non-motor disorders of Parkinson's are an important part of the clinical picture. …”
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A Review of the Healthcare and Social Care Needs of the Older Prisoner Population in England and Wales by Paul Gavin, Cody Normitta Porter, Finley MacDonald

“…This paper provides an overview of the main challenges facing older prisoners in the context of their health and social care needs, including the development of mental health problems such as Alzheimer’s and dementia, as well as challenges related to mobility and engaging in structured activities in prison. …”
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Cognitive Phenotypes, Brain Morphometry and the Detection of Cognitive Decline in Preclinical AD by Mark W. Jacobson, Linda K. McEvoy, Anders Dale, Christine Fennema-Notestine

“…Identifying a preclinical phase of Alzheimer’s Disease (PCAD) that is distinct from cognitive changes in healthy aging continues to be a major research focus. …”
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Multipotent Effect of Clozapine on Lipopolysaccharide-Induced Acetylcholinesterase, Cyclooxygenase-2,5-Lipoxygenase, and Caspase-3: In Vivo and Molecular Modeling Studies by Minhajul Arfeen, Devendra Kumar Dhaked, Vasudevan Mani

“…Alzheimer’s disease (AD) is the most common cause of dementia, and the inhibition of acetylcholinesterase (AChE) is a key approach in treating AD. …”
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