Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

“…So, the proposed solution to this problem is to create a COPD identification system to diagnose COPD so that COPD can be known early and can be given early treatment to inhibit worsening of lung conditions. The system also uses an artificial intelligence system so that the diagnosis process is faster, precise, and consistent so that it does not depend on the sensitivity of the ear and the doctor's expertise. …”
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Effects of Chemical Fertilizer Reduction Combined with Straw and Organic Fertilizer Application on Soil Acidification Mitigation and Erosion Control by SHEN Mengxue, HAO Rui, LIU Xinwei, WEI Wanhao, CAO Yunfei, SHU Hujia, HAO Zongyu, WANG Huyu, WANG Ling, SHI Zhihua

“…Additionally, the total exchangeable base increased by 7.63%~34.68%, and the total nitrogen and organic matter contents in the soil also significantly increased (by 19.22%~62.86% and 18.43%~61.50%, respectively). …”
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Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study by Gaoyang Li, Shrikant S. Kolan, Franco Grimolizzi, Joseph Sexton, Giulia Malachin, Guro Goll, Tore K. Kvien, Tore K. Kvien, Nina Paulshus Sundlisæter, Manuela Zucknick, Siri Lillegraven, Espen A. Haavardsholm, Espen A. Haavardsholm, Bjørn Steen Skålhegg

“…The predictive power of each feature was assessed using a composite measure derived from individual algorithm estimates.ResultsThe model demonstrated a mean AUC-ROC of 0.75-0.76, with mean sensitivity of 0.77-0.81, precision (also referred to as Positive Predictive Value) of 0.77-0.79 and specificity of 0.63-0.66 across the criteria. …”
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Association of lower-limb strength with different fall histories or prospective falls in community-dwelling older people: a systematic review and meta-analysis by Ringo Tang-Long Zhu, Jenny Jing-Jing Zuo, Ke-Jing Li, Freddy Man Hin Lam, Arnold Yu Lok Wong, Lin Yang, Xue Bai, Man Sau Wong, Timothy Kwok, Yong-Ping Zheng, Christina Zong-Hao Ma

“…Low quality of evidence showed that the lower peak sit-to-stand power could also discern fall history (SMD & 95% CI: -0.58 [-0.96, -0.20]). …”
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Implementasi Data Mining untuk Deteksi Penyakit Ginjal Kronis (PGK) menggunakan K-Nearest Neighbor (KNN) dengan Backward Elimination by Ikhsan Wisnuadji Gamadarenda, Indra Waspada

“…Based on sources from BPJS Kesehatan, CKD care is the second largest ranking of financing after heart disease. CKD detection also requires many attributes, so it requires quite expensive costs. …”
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Other novel delivery options may also affect immune responses, including T-cell activation and tumor-antigen presentation changes. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…Outer membrane vesicles (OMVs), secreted by Gram-negative bacteria, are nanospherical structures that can display or deliver antigens while also providing adjuvant activity through pathogen-associated molecular patterns (PAMPs). …”
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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

“…Results: Our findings suggest that SM has antioxidant and neuroprotective potential, as evidenced by a decrease in ROS accumulation, Ca2+ overload, mitochondrial membrane potential (MMP) loss, and apoptosis in HT-22 cells subjected to glutamate-induced oxidative stress. The extract also increased SOD2 levels and decreased cleaved caspase-3 levels across various treatment sets. …”
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NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma by Chao-Yan Yao, Hang-Tian Tao, Jin-Jin He, Feng-Yi Zhu, Cui-Qing Xie, Yu-Na Cheng, Ji-Qin Li, Zhuang-Zhuang Liu, Chun-Yu Hou, Xue-Li Liu, Yong-Li Fan, Dong Fang, Xin-Rui Lv

“…Knockdown of β-catenin also reversed NUAK1-mediated PD-L1 expression in HCC cells. …”
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Current trends of unicompartmental knee arthroplasty (UKA): choosing between robotic-assisted and conventional surgeries and timing of procedures by Kelvin S. C. Cheung, Kai Chun Augustine Chan, Amy Cheung, Ping Keung Chan, Michelle Hilda Luk, Kwong Yuen Chiu, Henry Fu

“…Abstract Background With robotic advancements in UKA technology, we sought to explore if robotic-assisted UKA could translate to clinical benefits such as reduced hospital stays and lowered emergency readmissions. Also, current utilization trends of UKA and choice of procedure timing (unilateral [uUKA] vs. one-staged bilateral UKA [biUKA]) could be explored. …”
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Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a prospect... by Zeyan Liu, Jinbo Wang, Yanfang Yang, Jinglin Cheng, Min Yang, Ye Zhang

“…In the validation set, EAMI also demonstrated good predictive performance for MACE. …”
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Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment by Jingwen Yang, Chenquan Qiu, Renhai Tang, Wenbin Dong, Enlong Yao, Huyunzhao Wang, Shuwen Lin, Minyang Xiao, Zuyang Zhang, Jin Niu, Liru Fu, Lijun Song, Xuehua Li, Yuhua Shi, Xiaowen Wang

“…The participants in our study showed a preference for confidentiality regarding the testing status (β = 1.82, p < 0.001), for the test being available at hospitals (β = 0.72, p < 0.001), and for the test being administered by physicians (β = 0.74, p < 0.001). We also observed that having support services was preferable (β = 0.50, p < 0.01) to support services not being available. …”
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Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis by Shumeng Ren, Yuhang Chen, Yu Liu, Qiuyi Lv, Jing Peng, Lei Song, Yihuai Zou, Hua Zhang, Xing Chen

“…The Visual Analog Scale in the acupuncture group was lower [MD = −1.44, 95%CI (−1.81, −1.07), I2 = 94.5%, P &lt; 0.001]. The acupuncture also showed an improvement in the ability of daily living [MD = 12.19, 95% CI (8.50, 15.87), I2 = 97.2%, P &lt; 0.001] and the symptoms of neurological deficit [Standardized Mean Difference (SMD) = −1.53, 95%CI (−2.04, −1.03), I2 = 89.7%, P &lt; 0.001].ConclusionsThe current best evidence shows that acupuncture has advantages in raising the effective rate, alleviating sensory disturbance, relieving pain, enhancing the ability of daily living, and improving the symptoms of neurological deficits for somatosensory deficits after stroke compared with the control group. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Right grip strength was also identified as an important factor associated with all cognitive domains except general cognition (β ranged between 0.04 and 0.12). …”
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Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

“…Moreover, lentivirus-mediated HINT2 overexpression not only alleviated AP-induced ATP depletion, but also relieved inflammatory responses and cell necrosis. …”
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Ethnobotanical survey of medicinal plants used in management of breast cancers in Qatar by Rasha.S.Abo El Alaa, Hend Al-Jaber, Fatima Al Zahraa Chokor, Abdullah A. Shaito, Layla Al-Mansoori

“…The literature survey also uncovered that most plants are reported to induce apoptosis through specific pathways, while others showed chemo-sensitization effects and cancer-induced mutation prevention. …”
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Advancements in 3D printing technologies for personalized treatment of osteonecrosis of the femoral head by Tingting Chen, Lincong Luo, Jiaying Li, Jiamin Li, Tao Lin, Mingrui Liu, Hang Sang, Xinyu Hong, Jiahao Pu, Wenhua Huang

“…These advancements not only enhance treatment efficacy but also pave the way for translating laboratory findings into clinical applications.…”
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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Chemotherapy-free option lenvatinib plus anti-programmed cell death protein-1 (PD-1) combination therapy has shown promising results in several malignancies including ovarian cancer, but the toxicity of a high starting dose of lenvatinib is also notable and needs to be improved. Our previous pilot study indicated that a reduced starting dose of lenvatinib may maintain comparable anti-tumor activity with favorable safety in heavily pre-treated ovarian cancer. …”
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Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…Cigarette smoking status was also measured.Results We used weighted regression models to determine the association between ENDS device type current regular use and age group and the association between each ENDS type current regular use and smoking status separately for each age group. …”
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Level of fecal neopterin and calprotectin in asymptomatic and symptomatic norovirus-infected children with malnutrition in Indonesia by Anisa Lailatul Fitria, Zayyin Dinana, Aussie Tahta Maharani, Alinda Syifa Fumizuki, Faiz Nabila Mumtazya, Dominikus Raditya Atmaka, Laura Navika Yamani, Juniastuti, Maria Inge Lusida, Soetjipto, Septa Indra Puspikawati

“…Results: The level of fecal neopterin (mean ± SD, 15.46 ± 1.75 nmol/L and 15.12 ± 2.41 nmol/L; p-value: 0.744) and calprotectin (mean ± SD, 184.35 ± 35.09 ng/ml and 177.95 ± 49.55 ng/ml; p-value: 0.457) between ANV and SNV was comparable, also between Mal and Healthy groups. Meanwhile, the level of both biomarkers was significantly different in norovirus positive group and norovirus negative group (p-value < 0.000). …”
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