Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation by Ting Shen, Jing Yu, Bin Xie, Cuiping Huang, Jingjie Cui, Kefu Liu, Chunyu Liu, Chao Chen

“…Downregulating PRMT7 in neural progenitor cells (NPCs) decreased proliferation, increased neuronal differentiation, and also led to longer neurites in these neurons. Conversely, overexpressing PRMT7 enhanced NPC proliferation and reduced neuronal differentiation. …”
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Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia by Abdilahi Ibrahim Muse, Abdilahi Ibrahim Muse, Mahdi Yonis Kayat, Mohamed Harir Aden, Jemal Beksisa Shuramu, Shikur Mohammed, Musse Ahmed Ibrahim, Musse Ahmed Ibrahim, Binyam Mohammedbirhan Berhe, Ahmed Abdi Kalinle, Sahardiid Ali Abdilahi

“…Special focus should be given to vaccine cold chain management in the zone and its districts with high vaccination coverage but also a high measles incidence rate. An investigation should be done into the associated factors of the higher incidence despite its vaccination coverage.…”
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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…Optn overexpression led to a 9.7% delay in the onset of disease and improved motor performance in SOD1G93A mice. Optn overexpression also ameliorated the MNs loss by 46.8%. Moreover, all these ameliorating effects induced by Optn overexpression might be due to the inhibition of cellular apoptosis, improvement of mitochondrial quality, regulation of mitochondrial dynamics, promotion of mitophagy, and anti-inflammatory properties.ConclusionOur data demonstrate that Optn overexpression protects MNs, inhibites cellular apoptosis, improves mitochondrial quality and regulates neuroinflamation in SOD1G93A mice at the pre-symptomatic stage.…”
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Bayesian reinforcement learning models reveal how great-tailed grackles improve their behavioral flexibility in serial reversal learning experiments by Lukas, Dieter, McCune, Kelsey, Blaisdell, Aaron, Johnson-Ulrich, Zoe, MacPherson, Maggie, Seitz, Benjamin, Sevchik, August, Logan, Corina

“…The changes in behavioral flexibility that grackles showed in their experience of the serial reversals also influenced their behavior in a subsequent experiment, where individuals with more extreme rates or sensitivities solved more options on a multi-option puzzle box. …”
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UBE2T/CDC42/CD276 signaling axis mediates brain metastasis of triple-negative breast cancer via lysosomal autophagy by Lin Li, Rong Fu, Yan Chen, Jin Yao, Xiaobing Jiang, Tao Liang, Jun jun Li, Qian zhi Chen, Liang Liang Shi, Ming Xing Xie, Xin Wei Qiao, Qi Hong Cheng, Min Jie Wang

“…Finally, animal experimental results also showed that inhibition of UBE2T elevated the TNBC sensitivity to immune checkpoint CD276 blockade and inhibited BrM of TNBC.Conclusions In conclusion, our results indicate a new mechanism whereby UBE2T-mediated ubiquitination positively controls the UBE2T/CDC42/CD276 axis to upregulate tumor cell expression of CD276 and thereby impair CD8+ T cells function, ultimately leading to tumor cell immune escape and BrM.…”
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Identifikasi Tanaman Obat Indonesia Melalui Citra Daun Menggunakan Metode Convolutional Neural Network (CNN) by Budi Setiyono, Muhammad Riv’an Arif, Qonita Qurratu Aini, Theophil Henry Soegianto, Jasti Ohanna, Ricky Andrean Fernanda Gunawan, Ayu Putri Rizkia

“…In addition, the authors also use primary data on herbal plant leaves obtained from the Surabaya herbal village. …”
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Short-term effects of olive-mill-wastes-derived biochars amendment and arbuscular mycorrhizal fungi inoculation on growth of maize (Zea mays) and mycorrhizal colonization by Minkosse, Christiane, Langenfeld, Aude, Azzaz, Ahmed Amine, Jeguirim, Mejdi, El-Bassi, Leila, Akrout, Hanene, Jellali, Salah, Ghimbeu, Camélia Matei, Nassr, Najat

“…A greenhouse experiment was also conducted to study the effect of AMF spores and biochars adding on the growth of maize plants. …”
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INSTRUMENT ASSESSMENT IN STUDENT LEARNING OUTCOME FOR FACTUAL AND CONCEPTUAL HOTS ON SCIENCE EDUCATION by Endang Widi Winarni, Endina Putri Purwandari, Rinto Hartono

“…The cognitive level questions were categorized into three levels, with 40% categorized in C4, 33.33% in C5, and 26.67% in C6. The study also found that 46.67% of the questions assessed factual knowledge, while 53.33% assessed conceptual knowledge. …”
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Nursing faculty readiness to teach online: a survey of nursing educators from Saudi Arabia and the UK by Mansour Mansour, Naim Abdulmohdi, Abd Alhadi Hasan, Hana Abu-Snieneh, Rani Shatnawi, Firas Taysir Abu-Sneineh, Sahar Elmetwally A. Badawi

“…Results Nursing Faculty from Saudi Arabia universities have scored significantly higher Median score than their British counterparts on the Course Design subscale (z=-2.6, p = 0.01) and Time Management subscale (z=-4.403, p = 0.001), and Nursing Faculty who completed a training course before they can teach online have also scored significantly higher median score than those who didn’t on the same two subscales respectively (X 2 = 6.15, df = 2, p = 0.05), (X2 = 12, df = 2, p = 0.002). …”
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Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid–Liquid Phase Separation and Ferroptosis-Related Genes by Wenchao Chen, Ting Zhu, Xiaofan Pu, Linlin Zhao, Senhao Zhou, Xin Zhong, Suihan Wang, Tianyu Lin

“…Then the effects of NRAS on the development of HCC and ferroptosis were also detected. Results: We identified 24 DEGs overlapping among HCC-specific, LLPS, and ferroptosis-related genes. …”
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Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

“…Alpinia officinarum, commonly known as Galangal, is not only widely used as a medicinal plant but also holds significant ornamental value in horticulture and landscape design due to its unique plant structure and floral aesthetics in China. …”
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Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

“…The interventional methods for biliary drainage, their success rate and patient outcome were also investigated.MethodsElectronic medical records were reviewed to identify patients hospitalized for obstructive jaundice at Peking Union Medical College Hospital, who had previously undergone subtotal gastrectomy. …”
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Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells by Bingxue Nie, Daoqiang Zhang, Xin Liu, Chengying Lei, Zhiruo Li, Nan Zhang, Shuping Zhang, Yiju Wei, Jie Zhang

“…This study provides additional insights into the structure-activity relationship for PM’s toxicity. It also sheds light on further investigations on the detoxication of PM.…”
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Provincial distribution and predictors of desire for more children among married and cohabiting women in Sierra Leone by Augustus Osborne

“…This high fertility rate impacts population growth, straining resources like healthcare and education. It can also have consequences for women's health and well-being. …”
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Notation publications in the context of musical life in Lithuania in the XVI-XVII centuries by Jūratė Trilupaitienė

“…The distinct decrease in the printing of hymns scored for many voice parts after Radvila's death in 1565 confirms his influence. It may also be that Radvila financed the 1565 Cracow publication of the tabulature of Valentin Bakfark (Bacfark) living in Vilnius. …”
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ALMA FACTS. II. Large Scale Variations in the 12CO(J = 2 – 1) to 12CO(J = 1 – 0) Line Ratio in Nearby Galaxies by Shinya Komugi, Tsuyoshi Sawada, Jin Koda, Fumi Egusa, Fumiya Maeda, Akihiko Hirota, Amanda M. Lee

“…We find, however, that the radial gradient in r _21 is bimodal, where a group containing all SA galaxies prefer constant or very shallow r _21 gradients out to 40% of the optical radius, while another group containing all SB galaxies have a steep r _21 gradient, decreasing by ∼20% before 40% of the optical radius, which also corresponds to the radius of the stellar bar. …”
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Enough Sulfur and Iron for Potential Life Make Enceladus’s Ocean Fully Habitable by Weiming Xu, Can Liu, Ao Zhang, Maggie Lau, H. James Cleaves, Fang Huang, Christopher R. Glein, Jihua Hao

“…Our predicted availabilities of Fe and S are close to measured concentrations in inhabited terrestrial serpentinization fluids, implying sufficient nutrients to support potential life. Our results also suggest that the reduction of ferric iron or sulfate might supply enough energy for chemotrophic metabolisms based on these reactions to complement previously proposed methanogenesis. …”
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Presenting a Leadership Empowerment Model through Sense-making by Using the Cognitive and Behavioral Scripts by Hamid Zare, Aliasghar Pourezzat, Hasan Zareei Matin, Arezoo Salmani

“…This research is firmly grounded in an interpretive paradigm and is classified under qualitative methodologies, employing an inductive approach that also incorporated a retrospective analysis to deepen the understanding of the underlying themes. …”
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Two-dimensional semantic morphological feature extraction and atlas construction of maize ear leaves by Hongli Song, Hongli Song, Weiliang Wen, Weiliang Wen, Ying Zhang, Ying Zhang, Yanxin Zhao, Xinyu Guo, Xinyu Guo, Chunjiang Zhao, Chunjiang Zhao, Chunjiang Zhao

“…The methodology presented in this study offers novel insights into the construction of semantic models for the morphology of maize and the identification of cultivars. It also provides a theoretical and technical foundation for the generation and drawing the leaf shape based on semantic 2D morphological and structural features.…”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…Methods In this cross-sectional study, we performed a broad assessment of forty-one signs of skin ageing and characterised the phenotypes that constituted key components of skin ageing. We also explored the interrelationship among forty-one skin ageing phenotypes using Spearman’s Correlation and Principal Component Analysis. …”
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