Multi-omics reveals that ST6GAL1 promotes colorectal cancer progression through LGALS3BP sialylation by Yuanchao Shi, Zhenzhong Pan, Jingwei Duan, Zexing Wang, Yiliang Fang, Bo Tang, Quanlin Guan

“…Treatment with sialidases (neuraminidases, NAs) also blocked the protumor activity of ST6GAL1. Thus, ST6GAL1-induced increased sialylation of substrates such as LGALS3BP and upregulation of protumor genes promote CRC tumorigenesis and chemoresistance, which provides important perspectives and new targets for the treatment of CRC. …”
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Preparation of doped spinel LiMn2O4 cathode using α-MnO2 for high-performance Li-ion batteries by Jean Pierre Mwizerwa, Khuram Usman, Sefiu Abolaji Rasaki, Pamphile Ndagijimana

“…However, LMO often shows low robustness in terms of cycle life. Its activity is also irreversible due to Mn dissolution, Jahn–Teller distortion, and phase changes that normally occur within its crystal lattice. …”
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Chemical analysis of buffalo meat in a self-consumption system in northeastern of Argentina by Gladis Rébak, Gladys Obregón, Diego Gómez, Laura Vázquez-Acosta, Mariano Pino, Julia Obregón, Rosa Molina, Victoria Cantero, Luz Segovia-Espinola

“…The fatty acid profile was also determined, with extraction according to the Folch technique and gas chromatography (GC), identifying saturated (SFA), unsat-urated (UFA): monounsaturated (MUFA) and polyunsaturated (PUFA) fatty acids present in the intramuscular fat. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…The immune microenvironment of HVEM KO mice bearing mouse lung cancer cell was also evaluated. Co-cultured system and phenotype assays facilitated the examination of Jurkat T cells’ effect on A549 and H1299 lung cancer cells. …”
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Green synthesis of magnetic type Zeolites 4A as catalyst for the elimination of quinoline yellow by the Fenton process: Optimization and kinetic investigation by Roland Urselin Noumsi Foko, Cyrille Ghislain Fotsop, Donald Raoul Tchuifon Tchuifon, Charles Banenzoué, Anatole Guy Blaise Azebaze

“…This work describes the hydrothermal synthesis and characterization of zeolite 4A (Zeo-4A) and magnetite zeolite (Zeo-4A@Fe3O4) from Cameroonian raw kaolin. The study also explores the efficiency of Zeo-4A@Fe3O4 for the removal of quinoline yellow (E104) via Fenton process. …”
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FAN score predicts prognosis after platinum-based first-line chemotherapy in patients with metastatic urothelial carcinoma by Yu Ishizuya, Atsunari Kawashima, Yuki Horibe, Akinaru Yamamoto, Masaru Tani, Akihiro Yoshimura, Liu Yutong, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Toshihiro Uemura, Gaku Yamamichi, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Norio Nonomura

“…Multivariable analysis showed that Fib-4 index (HR 3.85, 95% CI 1.09–13.58, p = 0.036), ALBI score (HR 1.53, 95% CI 1.01–2.31, p = 0.045), and NLR (HR 1.76, 95% CI 1.14–2.71, p = 0.010) were independently associated with PFS. The FAN score was also associated with PFS (HR 2.56, 95% CI 1.62–4.05, p < 0.001). …”
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Impact of the Late Miocene Cooling on the loss of coral reefs in the Central Indo-Pacific by B. F. Petrick, L. Reuning, M. Pfeiffer, G. Auer, L. Schwark

“…During the LMC, SST at ODP Site 811 declined by about 2 °C, while cooling lasted from 7.0 to 5.4 Ma. This cooling has also been seen in other parts of the Central Indo-Pacific. …”
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Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery by Francisco Javier Hermoso-Pinilla, Aitor Valdivia, María-José Camarasa, Tiziana Ginex, Francisco Javier Luque

“…Furthermore, this study also aims to highlight the efforts made in exploiting the structural information in conjunction with molecular modeling techniques to discern the mechanism of action of the fusion inhibitors and to assist the design and interpretation of structure-activity relationships of novel lead compounds will be highlighted. …”
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Extreme Temperature Events in Kazakhstan and Their Impacts on Public Health and Energy Demand by Parya Broomandi, Alfrendo Satyanaga, Mehdi Bagheri, Mostafa Hadei, David Galán‐Madruga, Ali Mozhdehi Fard, Adib Roshani, Aram Fathian, Amir Nourian, Michael Leuchner, Klaus Reicherter, Mehdi Hamidi, Prashant Kumar, Jong Ryeol Kim

“…Shifts in energy demand are also unveiled with a noticeable spike in cooling‐degree days and a reduction in heating‐degree days. …”
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Machine learning-based plasma metabolomics for improved cirrhosis risk stratification by Jingru Song, Ziwei Gao, Liqun Lai, Jie Zhang, Binbin Liu, Yi Sang, Siqi Chen, Jiachen Qi, Yujun Zhang, Huang Kai, Wei Ye

“…Similarly, the combination of metabolomics with APRI also improved predictive performance compared to APRI alone (Harrell’s C: 0.747 vs. 0.718, ΔC = 0.029, 95% CI 0.022–0.035, NRI: 0.378 [0.366–0.389]). …”
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Model Evaluasi Usability Menggunakan Confirmatory Factor Analysis pada KRS Online by Endah Ratna Arumi, Pristi Sukmasetya, Agus Setiawan

“…Usability evaluation was also doing in this study to get the value of the usability level of this KRS Online interface. …”
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PROSPECTS FOR THE DEVELOPMENT OF BIODIESEL PRODUCTION IN UKRAINE WITH CONSIDERATION OF SOCIO-ECONOMIC AND ENVIRONMENTAL EFFICIENCY by Ihor Kupchuk, Tatiana Yemchyk, Yaroslav Gontaruk

“…The study's originality lies in the development of an algorithm for the operation of energy co-operatives, with the objective of meeting the needs of agricultural enterprises for biodiesel and concentrated feeds. The study also includes the development of a universal methodology for assessing the socio-economic and ecological efficiency of biodiesel production.…”
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Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…The “Cause of Death Panel” will finalize MITS informed cause of death following the customized protocol for the project and the cause so derived will be compared with that obtained by the review of deaths by the MPDSR committees of the hospitals. …”
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Klasifikasi Ulasan Palsu Menggunakan Borderline Over Sampling (BOS) dan Support Vector Machine (SVM) (Studi Kasus : Ulasan Tempat Makan) by Aisyah Awalina, Fitra Abdurrachman Bachtiar, Indriati Indriati

“…The search for reviews was triggered because visitors were not aware of the services of the place. Reviews can also benefit sellers, because they know the experience their visitors have had. …”
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Enhanced effect of radiofrequency ablation on HCC by siRNA-PD-L1-endostatin Co-expression plasmid delivered by Pengfei Chen, Kun Li, Jinwei Chen, He Hei, Jiaxin Geng, Nannan Huang, Mengyu Lei, Huijie Jia, Jianzhuang Ren, Chenwang Jin

“…Additionally, it induced tumor cell apoptosis, inhibited proliferation and migration, and increased the infiltration of T lymphocytes, granzyme B+ T cells, and CD86+macrophages within tumors. There was also a notable rise in T and NK cell populations in the spleen. …”
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Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…Blood routine indicators were also found to be correlated with gut microbiota composition.ConclusionThe findings of this study provide compelling evidence that gut microbiota diversity and composition are significantly altered in children with peanut allergy. …”
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Investigating the Use of Generative Adversarial Networks-Based Deep Learning for Reducing Motion Artifacts in Cardiac Magnetic Resonance by Ma ZP, Zhu YM, Zhang XD, Zhao YX, Zheng W, Yuan SR, Li GY, Zhang TL

“…For the 37 images with real-world artifacts, the Tenengrad Focus Measure showed a significant enhancement, rising from 6.06± 0.91 to 10.13± 0.48 after artifact removal. Subjective ratings also increased from 3.03± 0.73 to 3.73± 0.87 (P< 0.001).Conclusion: GAN-based deep learning technology effectively reduces motion artifacts present in CMR cine images, demonstrating significant potential for clinical application in optimizing CMR motion artifact management.Keywords: cardiac magnetic resonance, deep learning, generative adversarial networks, image quality, motion artifacts…”
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Eucalyptus grandis WRKY genes provide insight into the role of arbuscular mycorrhizal symbiosis in defense against Ralstonia solanacearum by Jianlang Zhang, Xinzhu Yang, Chunyu Huo, Xinyi Fan, Qiutong Liu, Zhihong Liu, Yu Su, Zujing Chen, Zujing Chen

“…IntroductionWRKY transcription factors are essential for plant growth, health, and responses to biotic and abiotic stress.MethodsIn this study, we performed a deep in silico characterization of the WRKY gene family in the genome of Eucalyptus grandis. We also analyzed the expression profiles of these genes upon colonization by the arbuscular mycorrhizal fungus (AMF) Rhizophagus irregularis (Ri) and infection with the bacterial pathogen Ralstonia solanacearum (Rs).ResultsA total of 117 EgWRKYs were identified. …”
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The Role of School Management Committee and Pupils' Performance in Government Primary Schools in RuhiJa Town Council Rubanda District. by Niwagaba, Alex

“…The recommendations included; the school management committee through meetings with members of teaching staff and their head teachers should advise them properly and allow them to execute their duties as expected in order to alleviate levels of understanding to children that lead to excellent academic performance; more research should be carried out to allow the school management committees not to dwell on advising head teachers only on matters of children's performance by suggesting strategies but also the entire stakeholders whose effort can promote academic performance of children in primary schools; need to formulate academic committees advised by the members of school management committee on how to perform through motivational element aiming at doing well academically to promote the names of the school; it is imperative that the schools get in touch with the members of the school management committees who have some formal education to quickly understand the value of education and how plans for developments of certain sectors in school especially academic performance could be made; need to foster supervision that involves cooperation towards pupils 'performance by all stakeholders; appointing an active team that can do supervision to let children advance academically is healthy.…”
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A Model for Organizational Preparedness of SMEs During COVID-19 Pandemic in Kigezi Sub-region in South Western Uganda. by Tamwesigire, Caleb, Nafiu, Lukman Abiodun

“…The study recommends that SME owners/managers should focus on improving their firms’ features; perfect the way they make decision by providing a critical dynamic resilience strategy framework to manage their SMEs during the crisis period. There is also need for government/NGO interventions in the area of subsidy for SME owners/managers during the pandemic to boost their businesses. …”
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