Tangeretin offers neuroprotection against colchicine-induced memory impairment in Wistar rats by modulating the antioxidant milieu, inflammatory mediators and oxidative stress in t... by Olalekan Bukunmi Ogunro, Mojisola Esther Karigidi, Gideon Ampoma Gyebi, Areej Turkistani, Ahmad H. Almehmadi

“…Results The biochemical analysis showed that chronic administration of tangeretin effectively reversed the colchicine-induced increase in the level/activity of lipid peroxidation, hydrogen peroxide (H2O2), myeloperoxidase (MPO), nitrite, reactive oxygen species (ROS), tumour necrosis factor-α (TNF-α), nuclear factor kappa B (NF-κB), interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), serotonin, dopamine, glutamate, amyloid beta (Aβ) peptide, and caspase-3. Tangeretin also reversed the colchicine-induced reduction in the level/activity of brain-derived neurotrophic factor (BDNF), amma-aminobutyric acid (GABA), acetylcholinesterase (AChE), glutathione S-Transferase (GST), glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), superoxide dismutase (SOD), reduced glutathione (GSH), and total thiol (T-SH) in rat brains. …”
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A decomposition analysis of sociodemographic factors and non-cigarette tobacco use as contributors to the change in smoking rates in South Africa between 2017/18 and 2021 by K Kali, O Ayo-Yusuf

“…A Blinda-Oaxaca decomposition analysis was also used to explore the roles of various sociodemographic factors, including any differences in the use of TNPs, that may explain any observed differences in smoking rates between 2017/18 and 2021. …”
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South African Open Distance Elearning Student: The Types, Effectiveness, and Preference of Feedback Support by Morakinyo Akintolu, Mohamed Ahmed Mitwally, Moeketsi Letseka

“…The findings indicate that proactive and prompt feedback significantly enhances student learning, emphasising the need for constructive comments within the ODeL framework. The study also identifies specific feedback forms requested by students to improve their educational experience. …”
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The assessment of routine health information system performance towards improvement of quality of reproductive, maternal, newborn, child and adolescent health services in Ondo and... by Victoria Oladoyin, Sunday Adedini, Kayode Ijadunola, Hassan Ogunwemimo, Olubunmi Folorunso, Elizabeth Chukwu, Ugo Okoli, Anthony Adoghe, Samuel Oyeniyi, Oniyire Adetiloye, Adesegun Fatusi

“…Data accuracy was 70.1% for Ondo and 40.4% for Ekiti (p <0.001); 82.9% of facilities in Ondo and 44.2% in Ekiti had complete data (p <0.001); almost all facilities (Ondo: 99.1%; Ekiti: 96.2%, p = 0.224) demonstrated data consistency; and, 82.9% of facilities in Ondo and 94.2% of facilities in Ekiti demonstrated timeliness in data submission (p = 0.048). Also, 70.1% (Ondo) and 78% (Ekiti) of facilities had quality improvement (QI) teams (p = 0.338); 53.5% (Ondo) and 77.1% (Ekiti) of QI teams regularly extracted data, calculated, and visualised prioritized indicators (p = 0.007); while 72.1% (Ondo) and 79.2% (Ekiti) regularly reviewed data and used it to make QI decisions (p = 0.367).…”
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Brood thermoregulation effectiveness is positively linked to the amount of brood but not to the number of bees in honeybee colonies by Godeau, Ugoline, Pioz, Maryline, Martin, Olivier, Rüger, Charlotte, Crauser, Didier, Le Conte, Yves, Henry, Mickael, Alaux, Cédric

“…Interestingly, mean brood temperature was also positively linked to the amount of brood, while its stability did not seem influenced by the size of the colony (number of bees or brood amount). …”
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Scaling of fractured rock flow. Proposition of indicators for selection of DFN based flow models by Davy, Philippe, Le Goc, Romain, Darcel, Caroline, Selroos, Jan-Olof

“…The third indicator on model variability is still problematic since the natural data show a higher variability than the models but the open fraction is also much more variable in the data than in the models.…”
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Renal transplant recipient and deceased-donor risk profiles at Wits Donald Gordon Medical Centre, Johannesburg, South Africa: A 9-year review by F van der Schyff, M Barnard, B Ströbele, M de Jager, R Britz, P Gaylard, J Loveland

“…Renal recipient risk scores also demonstrated low- to average-risk patients being transplanted, with a median Hennepin score of 2 - 4 points and a KTMI of 2 points. …”
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Rekayasa E-Aquaculture untuk Pemantauan Tambak Udang secara Realtime dengan Model Multipoint Node by Muhamad Komarudin, Hery Dian Septama, Titin Yulianti, Muhamad Aby Wicaksono

“…The Salinity, pH and temperature score besides being displayed on the display device at each node, it is also sent to the masterboard through data communication. …”
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Cluster analysis of cutting technique—a valuable approach for assessing anterior cruciate ligament injury risk? by Lasse Mausehund, Anri Patron, Sami Äyrämö, Sami Äyrämö, Tron Krosshaug

“…However, these clusters were formed based on sport- or task-related differences (Fisher's p &lt; 0.001, ARI = 0.83) rather than injury-related differences (Fisher's p = 0.417, ARI = 0.00). We also found two cutting technique clusters in the handball (ASS = 0.23) and football (ASS = 0.30) subsets with five kinematic variables. …”
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Evaluación del impacto del COVID-19 en la frecuencia de trastornos psicológicos en estudiantes de medicina de la Universidad Antofagasta. by Marcia Pereyra, Margarita Fuentes, Maria Jose Navarro, Francisco Montenegro, Karina Diaz, Camila Bradanovic, Carolina Madero, Elainne Doll, Valentina Delgado

“…En el área de la salud mental la puntuación global fue muy alto (31,7 de 38) indicando que hay posibilidad de que los estudiantes sufrieron un trastorno emocional que demostró un peor estado de salud mental, siendo el estado de ánimo el área más afectada. …”
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Revealing intra- and inter-container fruit quality heterogeneity within overseas refrigerated container shipments using a physics-based digital twin by Celine Verreydt, Tarl Berry, Leo Lukasse, Deniz Turan, Paul Cronje, Thijs Defraeye

“…Except for mass loss, the results showed limited quality gradients within the container. Also, when shifting the packaging type, the average quality of the cargo did not change significantly. …”
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Effect of extrusion processing on the structural, functional, and physicochemical properties of wheat and wheat-based products: A review by Junjie Chen, Qiang Liu, Siqi Zhao, Liping Guo, Xinbo Zhuang, Xuehong Chen, Tingting Tao, Chao Ding

“…., expansion ratio, water absorption index, water solubility index, texture, viscosity, and digestibility) of wheat-based products. We also discuss specific applications of extruded wheat products. …”
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Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…An approximation on mechanisms associated to this effect was evaluated on MCF-7 cells, it shows that the peptide induced apoptosis by activating intrinsic and extrinsic pathway, which correlates with the possibility of a specific interaction, and induces mitochondrial depolarization with release of oxygen reactive species. Also, this peptide induces a reduction in migration and invasion associated with a diminish in metalloprotease 9 activity and a lesser release of IL-6, IL-10 and arginase cytokines. …”
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Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands by Dekker, Joannes A. A., Mylopotamitaki, Dorothea, Verbaas, Annemieke, Sinet-Mathiot, Virginie, Presslee, Samantha, McCarthy, Morgan L., Olsen, Morten Tange, Olsen, Jesper V., van den Hurk, Youri, Brattinga, Joris, Welker, Frido

“…The assignment of the tool as whale bone adds support to the exploitation of whales by coastal Bronze Age populations, not just for meat, as previously suggested, but also for bone as a resource for tool production. …”
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Variabilidad intraespecífica en la calidad de semillas de especies forestales nativas en bosques montanos en el sur del Ecuador: Implicaciones para la restauración de bosques... by Ximena Palomeque, Andrea Maza, Juan Pablo Iñamagua, Sven Günter, Patrick Hildebrandt, Michael Weber, Bernd Stimm

“…En cuanto a la velocidad de germinación, individuos de especies como O. grandiflora e I. acreana mostraron un alto coeficiente en contraste a los individuos de O. heterochroma y M. pubescens. …”
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Age-related changes in DNA methylation in a sample of elderly Brazilians by Hayley Welsh, Caio M. P. F. Batalha, Weili Li, Nadja C. Souza-Pinto, Yeda A. O. Duarte, Michel S. Naslavsky, Esteban J. Parra

“…Differentially methylated regions (DMRs) were also identified using DMRcate. Gene ontology (GO) pathway enrichment analyses were performed to explore the functional significance of identified DMPs and DMRs. …”
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Association of liver biopsy pathology on outcome of patients undergoing heart transplantation by Lauren S. Eichenwald, MD, Raffi Karagozian, MD, Adam J. Eichenwald, PhD, John Morrissey, MD MBA, Saurav Kini, MD, Ariella Stein, MSCIS-HI, Amanda R. Vest, MBBS MPH

“…Results: There was no significant difference in the survival of patients with advanced fibrosis and early fibrosis over time (HR 1.54, CI 0.59–4.02, p = 0.5). Similarly, there was also no significant survival difference within groups who did (HR 0.78, CI = 0.26–2.33, p = 0.8) or did not (HR 1.00, CI 0.09–11.43, p = 0.9) receive transplants. …”
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Role of Computed Tomography in Predicting Programmed Death Ligand-1 Positivity in Gastric Adenocarcinoma by Yu ZH, Ma WQ, Ren JW, Zhang XT, Chu L

“…A nomogram was developed to assess the model’s predictive performance, which was evaluated using the receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). It was also compared with the model established by previous study.Results: Patients with PD-L1-positive gastric adenocarcinoma exhibited a higher prevalence of larger short diameters of lymph nodes (LNs) (≥ 1 cm), and lower CT attenuation values in the venous and delayed phases compared to those in the PD-L1-negative group. …”
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Lightweight AES Design for IoT Applications: Optimizations in FPGA and ASIC With DFA Countermeasure Strategies by Salman Ahmed, Nabihah Ahmad, Nasir Ali Shah, Ghulam E. Mustafa Abro, Ardhi Wijayanto, Abdinasir Hirsi, Abdul Rehman Altaf

“…However, the proliferation of IoT devices has also increased security risks, which requires robust protection mechanisms for sensitive data and critical infrastructure. …”
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High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding by Michell, Craig, Collins, Joanna, Laine, Pia K., Fekete, Zsófia, Tapanainen, Riikka, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.

“…The chromosomal assembly of the genome also demonstrates that the cell line has not acquired karyotypic changes during culture.…”
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