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9441
STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
Published 2021-02-01“…Consistent with a central role for DC in TLS formation, ADU S-100-activated mCD11c+ DCs also exhibited upregulated expression of TLS promoting factors including lymphotoxin-α (LTA), interleukin (IL)-36, inflammatory chemokines and type I interferons in vitro and in vivo. …”
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9442
Advances in Radiation Protection in Oral and Dental Radiology: Pragmatic Approaches and Recent Innovations
Published 2025-01-01“…The primary conclusions and relevant units of measurement are also included. According to the predefined inclusion and exclusion criteria, a total of 26 articles were systematically reviewed for this study. …”
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9443
Exploring sustainable construction: A case study on the potential of municipal solid waste incineration ashes as building materials in San Andres island
Published 2025-07-01“…The results indicated that the bottom ash does not exhibit pozzolanic activity per ASTM standards at 7 and 28 days. However, mortars and prefabricated concrete items incorporating bottom ash as aggregates showed compressive and flexural strength values greater than those set by the standards. …”
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9444
Challenges of early renal cancer detection: symptom patterns and incidental diagnosis rate in a multicentre prospective UK cohort of patients presenting with suspected renal cancer
Published 2020-05-01“…Comprehensive clinico-pathological and outcome data were also collected.Outcomes Type and frequency of reported symptoms, incidental diagnosis rate, metastasis-free survival and cancer-specific survival.Results Of 706 patients recruited between 2011 and 2014, 608 patients with a confirmed RCC formed the primary study population. …”
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9445
Immunodeficiency, Centromeric Instability, and Facial Dysmorphism (ICF) Syndrome: How HSCT alters the impairment of the DNA methylation process
Published 2025-02-01“…Advances in molecular biology and genetics enabled insights into the DNA methylation machinery, which allowed us to gain a more precise understanding of the pathogenesis of ICF and also opened up opportunities for the development of new therapeutic options. …”
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9446
The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i>
Published 2025-02-01“…Following subcutaneous injection of antagomiRNA-211 (chemical modification inhibitor), the expression levels of the <i>AP1S2</i> gene and protein were enhanced, and the localization in the hair follicle was also increased. Furthermore, reduction in melanin content in the skin was detected. …”
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9447
Borogon: Ethnonym and Ethnic History
Published 2024-11-01“…Those sources, however, provide only fragmentary information about the bearers of Borogon identity. It is also proposed the etymology, supported by linguistic data presented in different lexical and etymological dictionaries and recent results of researches on the development of historical phonetics of the Mongolic and Turkic languages. …”
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9448
Multimessenger Probes of Supermassive Black Hole Spin Evolution
Published 2025-01-01“…We show that the observed spin distribution is in agreement with a model that includes jet-driven spin-down, a key mechanism that acts to modulate spins across cosmic time at both high and very low specific accretion rates. The data also clearly prefer models with coherent accretion over models in which accretion disks rapidly switch from prograde to retrograde. …”
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9449
Effects of coenzyme q10 supplementation on metabolic and reproductive outcomes in obese rats
Published 2025-02-01“…Moreover, it caused a reduction in the number of AMH + follicles (p < 0.001), increasing follicular atresia (p < 0.05) and serum estradiol levels (p < 0.05). Obesity also altered the estrous cycle and reduced the ovulation rate (p < 0.05). …”
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9450
E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department
Published 2023-10-01“…The E-HEART Score was also compared with existing traditional scoring systems for risk-stratifying acute chest pain. …”
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9451
Trend analysis of precipitation and temperature in Lahaul-Spiti district, Himachal Pradesh, India
Published 2025-02-01“…Hence, it is essential to study the trends of temperature and precipitation for the region and also its effects on sustainable development. The objective of this study is to investigate the variability of rainfall and temperature on a monthly, seasonal, and annual basis from 1981 to 2021. …”
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9452
Understanding Citizens’ Response to Social Activities on Twitter in US Metropolises During the COVID-19 Recovery Phase Using a Fine-Tuned Large Language Model: Application of AI
Published 2025-02-01“…ConclusionsThe results show a gradual decline in sentiment and interest in restrictions across all 3 cities as the pandemic approached its conclusion. These results are also ensured by a sentiment estimation model fine-tuned on actual Twitter posts. …”
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9453
Arab representation in Israeli healthcare professions: achievements, challenges and opportunities
Published 2025-02-01“…In medicine, dentistry, and pharmacy, many of the licensed Arab health professionals had studied outside of Israel; this phenomenon also exists for nursing but is less widespread there. …”
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9454
Deteksi Pneumonia Menggunakan Citra Sinar-X Paru berbasis Residual Network
Published 2022-02-01“…In addition, the effect of data augmentation in the form of rotation and reflection was also compared. Furthermore, the effect of the image enhancement technique using CLAHE on pneumonia detection is performed. …”
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9455
New insights into the phylogeny and infrageneric taxonomy of Saussurea based on hybrid capture phylogenomics (Hyb-Seq)
Published 2025-01-01“…For the first time, we recovered a well-resolved nuclear phylogeny of Saussurea consisting of four main clades, which was also supported by morphological data. Our analyses show that ancient hybridization is the most likely source of deep cytoplasmic-nuclear conflict in Saussurea, and a phylogeny based on nuclear data is more suitable than one based on chloroplast data for exploring the infrageneric classification of Saussurea. …”
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9456
A Novel Convolutional Neural Network-Based Approach for Fault Classification in Photovoltaic Arrays
Published 2020-01-01“…It is observed that the proposed method involving fine-tuned pre-trained CNN outperforms existing techniques, achieving a high fault detection accuracy of 73.53%. Our study also highlights the importance of representative and discriminative features to classify faults (as opposed to the use of raw data), especially in the noisy scenario, where our method achieves the best performance of 70.45%. …”
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9457
Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B
Published 2025-02-01“…Multivariate Cox regression showed that elevated liver stiffness with shear wave elastography (Hazard ratio (HR) = 1.05, 95% Confidence interval (CI) 1.03–1.08, P < 0.001) and abnormal AFP at baseline (HR = 1.00, 95% CI 1.00–1.00, P < 0.001) were independent risk factors for abnormal AFP in CHB patients, while shear wave elastography (HR = 1.07, 95% CI 1.02–1.12, P < 0.001) was also independent risk factor for HCC. Similar results were obtained after propensity score matching (PSM) analysis. …”
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9458
Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study
Published 2025-02-01“…Interaction effects between BMI and key variables such as sex, race/ethnicity and other factors were also analyzed. Age-stratified analyses were performed for the groups aged 20–39 years, 40–59 years, and ≥ 60 years. …”
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9459
Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China
Published 2025-02-01“…Results Among the pre-frail respondents, those with lower social participation (AOR 0.55 [95% CI 0.44–0.69]) had less risk of inadequate medication adherence; while lower social connection (AOR 1.91 [95% CI 1.54–2.36]), lower trust (AOR 2.80 [95% CI 2.25–3.47]), lower cohesion (AOR 2.04 [95% CI 1.65–2.53]), and lower reciprocity (AOR 2.32 [95% CI 1.87–2.88]) were all related to higher odds of inadequate medication adherence. Also, lower social participation (AOR 0.54 [95% CI 0.40–0.74]) was linked to less risk of inadequate medication adherence, while lower trust (AOR 1.89 [95% CI 1.41–2.54]), lower cohesion (AOR 1.68 [95% CI 1.24–2.26]), and lower reciprocity (AOR 1.52 [95% CI 1.14–2.04]) were all found to have a greater odds of inadequate medication adherence in frail respondents. …”
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9460
Diurnal and Daily Variations of PM2.5 and its Multiple-Wavelet Coherence with Meteorological Variables in Indonesia
Published 2024-01-01“…Implementation of Multiple Wavelet Coherence (MWC) with various meteorological variables reveals that the combination of four parameters provides a stronger influence on the PM2.5 concentration in all the observed locations. Wavelet analysis also observes distinct scale periods that represent higher haze concentrations in Jakarta and Surabaya from May to September. …”
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