An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein... by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

“…The identified SNPs of chr25:11,177 on 5s_rRNA (small ribosomal RNA) (P < 0.05/nSNPs) were linked to ECM, the abundance alteration of Pseudobutyrivibrio_sp. (a genus that was also showed to be linked to the ECM production via the mWASs analysis), GH24 (lysozyme), and 9,10,13-TriHOME (linoleic acid metabolism). …”
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Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis by Juan Hu, Qiao Li, Shiqiu Jiang, Yingying Deng, Lan Yang, Mengyu Du, Shuxuan He, Fuxing Xu, Chaoying Yan, Wei Gao, Yansong Li, Yaomin Zhu

“…Mitochondrial dysfunction and neuronal impairment are hallmark features of Diabetes-Associated Cognitive Dysfunction (DACD), mitochondrial transplantation is also a therapeutic intervention for DACD. However, the precise mechanism underlying its therapeutic effects are not fully elucidated. …”
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Spireoside Controls Blast Disease by Disrupting Membrane Integrity of Magnaporthe oryzae by Xu Liting, He Kaiwei, Guo Chunyu, Quan Cantao, Ma Yahuan, Zhang Wei, Ren Lifen, Wang Long, Song Li, Ouyang Qing, Yin Junjie, Zhu Xiaobo, Tang Yongyan, He Min, Chen Xuewei, Li Weitao

“…Furthermore, spireoside was also effective in controlling sheath blight disease. …”
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Prenatal exposure to a mixture of organophosphate ester and organophosphorus pesticides in relation to child neurodevelopment in the Shanghai Birth Cohort by Hui Wang, Dezheng Fu, Xiaoning Liu, Xiaochen Chang, Siyu Guo, Xiaomeng Cheng, Ying Tian, Jinjun Ran, Jun Zhang, Shengju Yin

“…We utilized multivariable linear regression and Bayesian kernel machine regression (BKMR) to estimate associations with individual and mixture component, respectively. We also investigated whether these associations varied by child sex. …”
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Identifikasi Emosi Manusia Berdasarkan Ucapan Menggunakan Metode Ekstraksi Ciri LPC dan Metode Euclidean Distance by Siti Helmiyah, Imam Riadi, Rusydi Umar, Abdullah Hanif, Anton Yudhana, Abdul Fadlil

“…Besides the use of classification methods can also affect the results of emotional recognition.   …”
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Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis by Min Hu, Xinyu Meng, Tong Wang, Yifan Wang, Xiaodong Chen, Dongliang Xu, Wei He, Hongjia Zhang, Wenzheng Guo, Bo Jing, Siwei Zhang, Jianhua Xu, Beibei Sun, Xueqian Sun, Tingting Liu, Na Ni, Tongtong Zhang, Wenwen Cui, Xiaoyu Wu, Liping Xia, Feng Yao, Fang Zhang, Jing Du, Jiong Deng

“…Results Immunization with these live but ICD dying tumor cells induced potent tumor-specific anti-tumor T cell immunity, which not only protected host from challenge by these tumor cells in prevention and therapy in mouse model of lung metastasis, but also prevented tumors development in Gprc5a-ko mouse model of lung tumorigenesis. …”
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Mechanisms underlying the effects of cyanogenesis on development and reproduction of Tetranychus urticae: Insights from enzyme activity and gene expression aspects by Mufeng Wu, Xiao Liang, Ying Liu, Chunling Wu, Xingkui An, Zihua Zhao, Guifeng Hao, Ijiti Oluwole Gregory, Zhihong Li, Qing Chen

“…Besides, the population growth was also significantly suppressed. Furthermore, the sustainable activation of enzyme activity and the encoding gene expression related to physiological process such as detoxification (cytochrome P450, glutathione S-transferase, UDP-glucuronosyltransferase and β-cyanoalanine synthase), antioxidation (superoxide dismutase, catalase and peroxidase), neural transduction (acetylcholinesterase) and respiration (cytochrome c oxidase) were attributed to the detrimental impact on development and reproduction of TSSM. …”
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First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan by Khalid Salman, Sittna Hayder El Nagar, Abdel Rahim M. El Hussein, Mohammed A. El Hussein, Hadi M. Yassine, Hebah A. Al Khatib, Mashael Ali Al- Badr, Ibrahim Farah, Khalid A. Enan

“…Children under 5 years of age exhibited a higher nucleic acid detection rate compared to older age groups, suggesting the importance of molecular testing in younger patients particularly in the early detection of Parvovirus B19 during the acute phase of infection, before the body has developed detectable antibodies and also in immunocompromised children, who may not mount an antibody response detectable by serological methods. …”
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Strategi Penanganan Imbalance Class Pada Model Klasifikasi Penerima Kartu Indonesia Pintar Kuliah Berbasis Neural Network Menggunakan Kombinasi SMOTE dan ENN by Zaqiatud Darojah, Ronny Susetyoko, Nana Ramadijanti

“…To solve the imbalanced KIP Kuliah recipients data, we propose a hybrid sampling technique that combines the Synthetic Minority Over-Sampling Technique (SMOTE) and the Edited Nearest Neighbor (ENN) and also samples selected deletion method with a new scheme. …”
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Pemilihan Strategi Implementasi Kesehatan Digital Pada Kelompok Pengambil Keputusan Menggunakan Metode Vikor by Sri Kusumadewi, Rahadian Kurniawan

“…In comparison to SAW and TOPSIS, Vikor was also demonstrated to produce excellent results with a comparatively high α value (q=0.85). …”
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Informasi Dini Terhadap Penyakit Kanker Payudara berbasis Telepon Pintar by Hesti Lina Wiraswati, Savira Ekawardhani, Sarasati Windria, Arina Al Khaq, Fauzia Nurfitri, Dini Wahyuni, Nadya Rachmawati, Rusdi Toriq Baasin, Annissa Retno Arimdayu, Annisa Retno Arimdayu

“…Objective: To provide information service about breast cancer, and an explanation also simulation of how to do BSE based on a smartphone-based app. …”
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Carcinoembryonic antigen trajectory predicts pathological complete response in advanced gastric cancer after neoadjuvant chemotherapy by Yonghe Chen, Yonghe Chen, Yonghe Chen, Dan Liu, Kaikai Wei, Yi Lin, Yi Lin, Yi Lin, Zhong Wang, Qian Sun, Huashe Wang, Huashe Wang, Huashe Wang, Junsheng Peng, Junsheng Peng, Junsheng Peng, Lei Lian, Lei Lian, Lei Lian

“…We analyzed associations between these CEA trajectories, pCR, lymph node remission, and survival.ResultspCR was achieved in 10.4% (38/366) of patients. pCR rates were significantly higher in Type I (41%) and Type II (15.8%) trajectories compared to Type III (6.7%). Lymph node remission also correlated with CEA trajectories, with Type I having the highest proportion of ypN0 (79.2%). …”
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Mechanical chest compression increases intrathoracic hemorrhage complications in patients receiving extracorporeal cardiopulmonary resuscitation by Yoshihisa Matsushima, Tatsuhiro Shibata, Kodai Shibao, Rei Yamakawa, Miyu Hayashida, Toshiyuki Yanai, Takashi Ishimatsu, Takehiro Homma, Shoichiro Nohara, Maki Otsuka, Yoshihiro Fukumoto

“…Mediastinal hematoma (18.8% vs. 2.3%, p = 0.030) and hemothorax (20.8% vs. 4.7%, p = 0.049) were also more frequent in the mechanical group. The 180-day survival rates did not differ significantly between groups (27.7% vs. 25.0%, log-rank p = 0.540). …”
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Visualisasi Data Kriminal Wilayah Polres Musi Banyuasin by Fitri Purwaningtias, Muhamad Ariandi, Maria Ulfa

“…The purpose of this research is to help Sat Tahti employees in managing data on criminal prisoners quickly and easily using this Tableau and also being able to present graphic reports that are easy to read and understand by the Head of the MuBa Police. …”
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EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…Additional in vivo and in vitro experiments, including CCK-8 assays, colony formation and mouse xenograft models, were conducted to explore the biological role of NAT10-mediated ac4C modifications. We also evaluated and optimized a potential treatment strategy targeting NAT10. …”
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Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Moreover, the results of in vitro experiments revealed that SSA significantly inhibited the proliferative and migratory abilities of PC3 cells in a dose-dependent manner. Finally, SSA also induced G1-phase blockade and apoptosis in PC3 cells, further highlighting its potential role in prostate cancer treatment.ConclusionThe present study revealed that SSA exerts anti-tumorigenic effects in prostate cancer by targeting multiple pathways, laying a theoretical reference for its use as a therapeutic candidate for prostate cancer.…”
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Role of 18F-PSMA-1007 PET/CT-derived quantitative volumetric tumor parameters in cytoreductive radical prostatectomy selection for patients with low-volume metastatic hormone-sensi... by Junjie Fan, Ke Xu, Zhangdong Jiang, Chaosheng Gan, Hao Song, Guoqiang Gao, Guojing Wang, Qiyuan Kang, Liang Luo, Zhuonan Wang, Dalin He, XiaoYi Duan, Kaijie Wu

“…Moreover, among patients with higher prostate PSMA-TV and prostate PSMA-TV/whole-body PSMA-TV, cRP also significantly prolonged PFS compared with those without cRP (HR: 3.49; 95% CI: 1.49–8.18, P = 0.004; HR: 8.54; 95% CI: 2.47–29.50, P = 0.013). …”
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The triglyceride-glucose index trajectories are associated with cardiovascular diseases in people living with HIV: evidence from a prospective cohort study in China, 2005–2022 by Yinsong Luo, Liqin Sun, Yun He, Fang Zhao, Duo Shan, Fan Bu, Lingyun Ge, Xiaorui Li, Yiyao Hu, Xi Xiao, Hongzhou Lu, Jiaye Liu

“…After stratifying by sex, the spline curves in men were nearly identical to those observed in the overall HIV-infected population. While women also demonstrated a nonlinear association with a similar threshold (8.484), the relationship above the threshold was not statistically significant. …”
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De macrostructuur van het boek Samuël en de theologische implicaties daarvan by HJ Koorevaar

“…It deals with the institutions of priesthood (Eli and his sons), of propherism (Samuel and his sons) aud of kingship (Saul or David). Also David is moving toward destruction, but beacause of the intervention of  Jhwh, the fifth main part ends with David again. …”
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The geographical variation in grassland forage quality on the eastern Qinghai-Tibet Plateau is driven mainly by climate by Shulan Wu, Xiaotao Lü, Qinghua Liu, Erke Wuda, Liu Li, Chunzhang Zhao, Juanjuan Huang, Shuang Li, Youbang Hu, Wenzhi Du, Hewen Li, Chaoqun Chen, Lin Luo, Ali Raza, Chunying Yin

“…We examined forage quality of 45 alpine meadow communities over a 23.6 × 104 km2 area on the eastern Qinghai-Tibet Plateau in China. We also examined the variations and drivers of multiple forage quality indicators across regional scale. …”
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