Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study by Salam Al kindi, Salam Al kindi, Altaf Al-Mamari, Shoaib Al-Zadjali, Mohamed Al-Rawahi, Ali Al Madhani, Anil V. Pathare

“…This mutation affected the interaction with cofactor pyridoxal 5′-phosphate since the patient’s hemoglobin improved with oral administration of pyridoxine tablets. His iron overload also responded to sustained oral iron chelation therapy with deferasirox. …”
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Clinical and Cost Burden of Primary Sjögren’s Syndrome: Descriptive Analysis Using a US Administrative Claims Database by Sue Perera, Liyuan Ma, Raj Punwaney, Sulabha Ramachandran

“…Patients with extra glandular disease also incurred greater average annual costs (2.9 times) contributing to ≥2 times/year more resource use for outpatient services than patients with glandular disease only. …”
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Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study) by Hala Fayek Khalil, Nadia Ezz El Din Metwalli, Sara Magdy, Mohamed Shamel

“…After 15 min, Group II had the highest value, followed by Group I. HEDP also recorded the highest cell proliferation, followed by curcumin. …”
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Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease by Qian Wang, Yanhui Wang, Jian Li, Hong Liu, Shiyu Chen

“…Structural information is also crucial for optimizing the potency of bicyclic peptide ligands.…”
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Analysis of Forest Cover in the Tumba-Lediima Nature Reserve (RTL-DRC) by Sylvestre Frey, André Musas A Musas, Nestor Anzola Kibamba, Sebastien Kidushi Mboma, Tege Simboni Simboni, Djonive Munene Asidi

“…These activities have led to the fragmentation of critical habitats, putting endemic and threatened species at risk, while also compromising the ecological integrity of the reserve. …”
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A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data reveal... by Zhou An, Meichun Zeng, Xianhua Wang

“…Inverse variance-weighted methods of bidirectional Mendelian randomization also revealed that smoking per day was significantly associated with elevated risks of Barrett’s esophagus (odds ratio = 1.34, 95% confidence interval: 1.092–1.649, p  = 0.005), while Barrett’s esophagus was also a susceptibility factor for smoking per day (odds ratio = 1.05, 95% confidence interval: 1.017–1.087, p  = 0.003). …”
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Best practice mechanisms for biodiversity conservation law and policy by Callum Brockett, Katie Woolaston, Felicity Deane, Fran Humphries, Ethan Kumar, Amanda Kennedy, Justine Bell-James

“…Further, most western countries utilise the same legal mechanisms (also known as policy tools) for biodiversity conservation, although some countries implement these laws more effectively than others. …”
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Exploring Quality of Life in Adults Living With Late-onset Pompe Disease: A Combined Quantitative and Qualitative Analysis of Patient Perceptions from Australia, France, Italy, and... by Holly Lumgair, Lisa Bashorum, Alasdair MacCulloch, Elizabeth Minas, George Timmins, Drago Bratkovic, Richard Perry, Medi Stone, Vasileios Blazos, Elisabetta Conti, Raymond Saich

“…Participant experiences such as use of mobility or ventilation aids, caregivers, symptomology, and daily life impacts were also characterized. **Methods:** A 2-part observational study was conducted online between October and December 2023 using the 36-item short-form tool (SF-36) and a survey. …”
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Application of different edge detection methods for faults identification in Anza Basin, Kenya by Gege Li, Qing Chen, Bingqiang Yuan, Xianfeng Tan, Hao Chen, Xiaoyu Huang, Lang Pan

“…These techniques aim to effectively and rapidly extract or enhance weak anomaly information about geological bodies’ boundaries. They also aim to delineate the distribution range of field sources. …”
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Effectiveness of joint species distribution models in the presence of imperfect detection by Stephanie Elizabeth Hogg, Yan Wang, Lewi Stone

“…To understand how effective this JSDM is in practice, we also compare results to those from a JSDM that does not explicitly model detection but instead makes use of ‘collapsed data’. …”
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Examining The Impact of The COVID-19 Pandemic On Pediatric Orthopedic Cases: A Systematic Review and Meta-Analysis by Ahmadin Yusuf Rizal Susatyo, Nizar Al Rhaazi, Farhan Haidar Fazlur Rahman, Ismail Hadisoebroto Dilogo

“…Furthermore, in the perspective of the pediatric orthopedic surgical case, the pooled analysis also did not show any significant difference between both periods (RR 1.05, 95% CI 0.95 to 1.17, p=0.35). …”
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Total glucosides of paeony for rheumatoid arthritis: a protocol for a systematic review by Jing Luo, Guo-Yan Yang, Di-Er Jin, Ying-Ze Zhang, Jian-Ming Wang, Wei-Ping Kong, Qing-Wen Tao

“…Trial registers and reference lists of retrieved articles will also be searched to identify potential articles. …”
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Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity by Yujia Zhao, Dan Liu, Wenguang Yang, Wangxiao He, Jin Yan, Leiqing Yao

“…Overall, this work not only presents an alternative approach for targeting PD-L1-dependent cancer immune evasion, but also provides a modularized strategy for discovering specific regulators for target proteins in various diseases.…”
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Successful management of refractory epilepsy in creatine transporter deficiency with cannabidiol and clobazam: A case report by Maria Borrell‐Pichot, Carmen Fons, Susana Boronat, Alba Sierra‐Marcos

“…Behavioral improvement was also noted by his caregivers. No adverse effects were reported. …”
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Amine modified sodium alginate: Synthesis, characterization and in vivo evaluation in rainbow trout (Oncorhynchus mykiss) by Samira Salarvand, Seyed Amir Hossein Jalali, Nasrollah Mahboobi Soofiani, Alireza Allafchian

“…The in vivo results showed that amine-modified alginate treatments significantly increased non-specific immune parameters, including lysozyme activity, alternative complement activity, and serum bactericidal activity, and also enhanced intestinal bacterial population compared with the control and simple alginate treatments (P < 0.05). …”
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Combined effects of topography, soil moisture, and snow cover regimes on growth responses of grasslands in a low- mountain range (Vosges, France) by P.-A. Herrault, A. Ullmann, D. Ertlen

“…A low soil water recharge also appears to be pivotal in explaining the probability of browning at the study site. …”
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ASSESSING THE RESULTS OF TRAINING IN DIGITAL ENTREPRENEURSHIP IN THE AGE OF HIGH AND DEEP TECH by Oleg Kaminsky, Julia Yereshko, Sergii Kyrychenko, Maryna Duchenko

“…The education market is also undergoing changes, but university education is very slow to respond to digital processes. …”
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Using AI chatbots (e.g., CHATGPT) in seeking health-related information online: The case of a common ailment by Pouyan Esmaeilzadeh, Mahed Maddah, Tala Mirzaei

“…The study emphasizes considering not only the instrumental benefits but also the enjoyment derived from interacting with conversational AI for healthcare purposes. …”
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Research status of traditional &amp; complementary medicine systems across the world by Vedvati Bhapkar, Vallari Nisargand, Pawankumar Godatwar, Supriya Bhalerao

“…However, their scientific acceptance and mainstreaming falls short due to inadequacies in research. Also, available reports in this regard scarcely focus on their individuality and present them as a consolidated entity. …”
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Time Management According to the Perspective of the Late Tuan Guru Haji Nik Abdul Aziz: A Study of the Interpretation of Surah al-'Asr by Abdul Azib Hussain, Khairulnazrin Nasir, Rahim Kamarul Zaman, Hamidi Abdul Ghani

“…He was a former Menteri Besar, a scholar, politician, and preacher who was very influential in the archipelago. His name was also engraved in the book '50 Islamic Figures Influential in the World'. …”
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