Developing an Interpretable Machine Learning Model for Early Prediction of Cardiovascular Involvement in Systemic Lupus Erythematosus by Deng Z, Liu H, Chen F, Liu Q, Wang X, Wang C, Lyu C, Li J, Li T

“…Among seven evaluated algorithms, the Gradient Boosting Machine (GBM) demonstrated the best performance on the test set. …”
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A validated heart-specific model for splice-disrupting variants in childhood heart disease by Robert Lesurf, Jeroen Breckpot, Jade Bouwmeester, Nour Hanafi, Anjali Jain, Yijing Liang, Tanya Papaz, Jane Lougheed, Tapas Mondal, Mahmoud Alsalehi, Luis Altamirano-Diaz, Erwin Oechslin, Enrique Audain, Gregor Dombrowsky, Alex V. Postma, Odilia I. Woudstra, Berto J. Bouma, Marc-Phillip Hitz, Connie R. Bezzina, Gillian M. Blue, David S. Winlaw, Seema Mital

“…Non-canonical splice variants that disrupt mRNA splicing through the loss or creation of exon boundaries are not routinely captured and/or evaluated by standard clinical genetic tests. Recent computational algorithms such as SpliceAI have shown an ability to predict such variants, but are not specific to cardiac-expressed genes and transcriptional isoforms. …”
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Machine learning-based risk prediction model for pertussis in children: a multicenter retrospective study by Juan Xie, Run-wei Ma, Yu-jing Feng, Yuan Qiao, Hong-yan Zhu, Xing-ping Tao, Wen-juan Chen, Cong-yun Liu, Tan Li, Kai Liu, Li-ming Cheng

“…Methods First, data from 1085 suspected pertussis patients from 7 centers were collected, and ten key features were analyzed using the lasso regression and Boruta algorithm: PDW-MPV-RATIO, SII, white blood cells, platelet distribution width, mean platelet volume, lymphocytes, cough duration, vaccination, fever, and lytic lymphocytes.Eight models were then trained and validated to assess their performance and to confirm their generalization ability with external datasets based on these features. …”
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A Hybrid Deep Learning–Based Approach for Visual Field Test Forecasting by Ashkan Abbasi, PhD, Sowjanya Gowrisankaran, PhD, Wei-Chun Lin, MD, PhD, Xubo Song, PhD, Bhavna Josephine Antony, PhD, Gadi Wollstein, MD, Joel S. Schuman, MD, Hiroshi Ishikawa, MD

“…Subjects and Controls: A total of 1750 subjects (healthy and glaucoma patients) with 19 437 Humphrey VF (24-2 Swedish Interactive Threshold Algorithm) tests collected from longitudinal glaucoma cohorts at the University of Pittsburgh and New York University. …”
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Classification of Individuals With COVID-19 and Post–COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near–Real-Time Monitoring C... by Carlos Alberto Sanches, Andre Felipe Henriques Librantz, Luciana Maria Malosá Sampaio, Peterson Adriano Belan

“…Classification models were developed using supervised machine learning algorithms (decision tree, support vector machines, k-nearest neighbor, and neural networks) and evaluated through cross-validation. …”
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Development of a robust FT-IR typing system for Salmonella enterica, enhancing performance through hierarchical classification by Diego Fredes-García, Javiera Jiménez-Rodríguez, Alejandro Piña-Iturbe, Pablo Caballero-Díaz, Tamara González-Villarroel, Fernando Dueñas, Aniela Wozniak, Aiko D. Adell, Andrea I. Moreno-Switt, Patricia García

“…The IR Biotyper was used to acquire spectra from these isolates. Machine learning algorithms, including support vector machines, were trained to classify the isolates. …”
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Modeling and validation of wearable sensor-based gait parameters in Parkinson’s disease patients with cognitive impairment by Guo Hong, Guo Hong, Fengju Mao, Fengju Mao, Mingming Zhang, Fei Zhang, Fei Zhang, Xiangcheng Wang, Kang Ren, Kang Ren, Zhonglue Chen, Zhonglue Chen, Xiaoguang Luo, Xiaoguang Luo

“…Selected variables were used to train and evaluate six machine-learning models. The models’ predictive performance was comprehensively assessed using receiver operating characteristic (ROC) curves, area under the curve (AUC) values, decision curve analysis (DCA), calibration curves, precision-recall (PR) curves, and forest plots. …”
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A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. by Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg

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