Profiling of Bacterial Communities of Hospital Wastewater Reveals Clinically Relevant Genera and Antimicrobial Resistance Genes by Clemente Cruz-Cruz, Javier Gaytán-Cervantes, Carolina González-Torres, Andres Emmanuel Nolasco-Rojas, Miguel Ángel Loyola-Cruz, Laura Delgado-Balbuena, Josué Delgado-Balbuena, Marianela Paredes-Mendoza, María Concepción Tamayo-Ordóñez, Yahaira de Jesús Tamayo-Ordoñez, Emilio Mariano Durán-Manuel, Araceli Rojas-Bernabé, Carlos Alberto Jiménez-Zamarripa, Oscar Sosa-Hernández, Omar Agni García-Hernández, Esther Ocharan-Hernández, Paola Berenice Zárate-Segura, Elizabeth González-Terreros, Daniel Alejandro Ramírez-Villanueva, Claudia Camelia Calzada-Mendoza, Juan Manuel Bello-López

“…The findings emphasise the need to implement hospital waste management programmes and ideally specific treatment plants to minimise the associated risks and protect the environment and human health.…”
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Prevalence and screening of hemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in Yemeni blood donors by Mohammed A.W. Almorish, Ahmed M. E. Elkhalifa, Elsharif. A. Bazie, Elsadig Mohamed Ahmed, Isameldin Mohamed Abdalla Hamad, Omer M. Aburaida, Rabei M. Elbadry, Yasir S. Kaloda, Tarig Babikir Algak Khalid

“…Various tests were performed, including complete blood count (CBC), serum ferritin, sickling test, G6PD assay, NESTROF test and high-performance liquid chromatography (HPLC).Results The prevalence of hematological abnormalities among blood donors reached 68.9%, with functional RBC abnormalities at 51.9%, leukopenia at 10.4%, thrombocytosis at 1.9%, and thrombocytopenia at 4.7%. Additionally, hemoglobinopathies were found in 21.7% of donors, with β-thalassemia trait at 3.8%, sickle cell trait at 1.9%, and suspected α-thalassemia trait at 16%, while G6PD deficiency and iron deficiency were present in 12.3% and 17.9% of donors, respectively. …”
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Long-term Trends of PM2.5 Composition during Cold Seasons in Shanghai after Releasing Clean Air Action Plan by Ruoyan Wang, Xingnan Ye, Weijie Huang, Zhixiao Lv, Yinghui Yao, Fan Yang, Yinghua Liu, Juntao Huo, Yusen Duan

“…To coordinate the control of PM2.5 and O3 pollution, it is recommended to implement a renewable energy strategy for non-road mobile equipment in addition to promoting new energy vehicles.…”
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Aβ status assessment in a hypothetical scenario prior to treatment with disease‐modifying therapies: Evidence from 10‐year real‐world experience at university memory clinics by Matthias Brendel, Tandis Parvizi, Johannes Gnörich, Christof Elias Topfstedt, Katharina Buerger, Daniel Janowitz, Boris‐Stephan Rauchmann, Robert Perneczky, Carolin Kurz, Dirk Mehrens, Wolfgang G. Kunz, Julia Kusche‐Palenga, Agnes Bernadette Kling, Antonia Buchal, Elizabet Nestorova, Sara Silvaieh, Raphael Wurm, Tatjana Traub‐Weidinger, Sigrid Klotz, Günther Regelsberger, Axel Rominger, Alexander Drzezga, Johannes Levin, Elisabeth Stögmann, Nicolai Franzmeier, Günter U. Höglinger

“…Patients at borderline levels strongly benefit from additional Aβ PET imaging. Two‐cutoff CSF Aβ 42/40 and PET will allow effective treatment stratification.…”
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Investigation of Comorbidity and Risk Factors Analysis During Lumpy Skin Disease Outbreaks in India by Gundallahalli Bayyappa Manjunatha Reddy, Shraddha Bijalwan, Siju Susan Jacob, Sunil Tadakod, Snigdha Madhaba Maharana, Sudeep Nagaraj, Sai Mounica Pabbineedi, Chandana Ramesh Uma, Viveka Prabhu Balappa, Chethan Kumar Harlipura Basavarajappa, Pinaki Prasad Sengupta, Sharanagouda Shiddanagouda Patil, Baldev Raj Gulati

“…These findings underscore the importance of implementing targeted prevention and control strategies to mitigate disease impact in livestock populations.…”
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A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer☆ by S. Hussung, D. Akhoundova, C. Pistoni, D. Lenggenhager, A. Töpfer, C. Pauli, B. Pestalozzi, C. Britschgi, M. Zoche, M. Rechsteiner, H. Moch, A. Weber, R. Fritsch

“…Materials and methods: We implemented a stratified two-stage TMP algorithm for advanced PC. …”
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DATA 5.0—Data Acquisition, Translation & Analysis—a prospective urooncological data warehouse for the 21st century by Viktoria Schütz, Christine Geisler, Mathias Rath, Sarah Böning, Thomas Treber, Albrecht Stenzinger, Alexander Brobeil, Oliver Reinhard, Anette Duensing, Anette Duensing, Stefan Duensing, Stefan Duensing, Markus Hohenfellner, Magdalena Görtz

“…However, the transfer of existing data into a new environment proved to be technically challenging.ObjectiveTo migrate the existing data into a modern data warehouse (DATA 5.0) while maintaining data extraction functions. Additional requirements included FHIR connectivity, big data analyses and AI applications.MethodsTogether with SAP SE, DATA 5.0 was developed. …”
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High Precision Phase Noise Analysis Based on a Photonic-Assisted Microwave Phase Shifter Without Nonlinear Phase Distortion by Jian Wang, Wenting Wang, Renheng Zhang, Bei Chen, Dechao Ban, Ya Jin, Keqi Cao, Yu Liu, Ninghua Zhu

“…The proposed scheme utilizes a dual parallel Mach Zehnder modulator (DPMZM) and an optical bandpass filter (OBPF) to implement the photon-assisted microwave phase shifter. …”
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Food safety knowledge, attitudes, and practices among food handlers in collective catering in central Morocco by Rachid Amaiach, Abdelhakim El Ouali Lalami, Mouhcine Fadil, Rabia Bouslamti, Sanae Lairini

“…Training programmes that emphasize these dimensions of food safety need to be implemented. The findings of this study, carried out for the first time in Fez, will provide a solid basis for further research. …”
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Determinants of usefulness in professional behaviour change interventions: observational study of a 15-year national program by Nicole L Pratt, Andre Q Andrade, Vanessa T LeBlanc, Lisa M Kalisch-Ellett, Anna Moffat, Natalie Blacker, Kerrie Westaway, John D Barratt, Elizabeth E Roughead

“…No presentation or content features in the educational material were correlated with perceived usefulness.Conclusions The finding provides additional evidence encouraging the use of behaviour change techniques, in particular prompt and goal setting, in audit and feedback interventions.…”
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Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis by Fanjie Lin, Ken Lin, Donglei Li, Weiguo Kong, Jiayu Zhuang, Wei He, Xinguang Wei, Tianchi Xiao, Hao Zu, Zili Zhang, Wenju Lu

“…Moreover, the differentially expressed genes (DEGs) were obtained based on the bulk RNA-seq and microarray data. In addition, a machine learning-based integrative procedure for constructing a concordance plasma cells-related gene signature (PCRGS) was developed. …”
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Strategies to Reduce Left Anterior Descending Artery and Left Ventricle Organ Doses in Radiotherapy Planning for Left-Sided Breast Cancer by Umut Diremsizoglu, Nezihan Topal, Aykut Oguz Konuk, Ibrahim Halil Suyusal, Dogacan Genc, Onur Ari, Hasan Furkan Cevik, Aysegul Ucuncu Kefeli, Maksut Gorkem Aksu, Emine Binnaz Sarper

“…The potential risk of MACE can be significantly reduced by implementing this strategy.…”
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Hydroalcoholic extract of Punica granatum L. (pomegranate) leaf: A promising phytotherapeutic agent against oral pathogens by Luciana Cláudia Diniz Tavares, Mariana Simões de Oliveira, Bernardo Canêdo Martins, Daphne Fonseca Coppoli Lanferini, Benjamin Fragneaud, Antonio Carlos Sant’ana, Guilherme Diniz Tavares, Ana Carolina Morais Apolônio

“…Dental biofilm (DB) is a complex microbial structure in which implementing an appropriate approach to prevent its development is difficult due to the diversity of microorganisms and the genetic and environmental factors that contribute to its formation. …”
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Optogenetic control of horizontally acquired genes prevent stuck fermentations in yeast by David Figueroa, Diego Ruiz, Nicolò Tellini, Matteo De Chiara, Eduardo I. Kessi-Pérez, Claudio Martínez, Gianni Liti, Amparo Querol, José M. Guillamón, Francisco Salinas

“…Our results show that changes in gene expression for genes within this region can impact growth parameters and fermentation rate. We additionally found that the expression of various genes in region A is necessary to complete the fermentation process and prevent stuck fermentations under low nitrogen conditions. …”
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Associations Between Relative Age, Siblings, and Motor Competence in Children and Adolescents by Daniel González-Devesa, José Carlos Diz-Gómez, Pedro Vicente-Vila, Marta Domínguez Fernández, Miguel Rodríguez Rodríguez, Rocío Carballo-Afonso, Miguel Adriano Sanchez-Lastra, Carlos Ayán-Pérez

“…Further research should explore longitudinal designs and consider additional psychosocial and environmental variables to better understand how these factors influence motor competence development over time.…”
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Sustained Improvements After Intervention to Prevent Contrast‐Associated Acute Kidney Injury: A Randomized Controlled Trial by Michael E. Matheny, Elizabeth Carpenter‐Song, Iben M. Ricket, Richard J. Solomon, Meagan E. Stabler, Sharon E. Davis, Lisa Zubkoff, Dax M. Westerman, Chad Dorn, Kevin C. Cox, Freneka F. Minter, Hani Jneid, Jesse W. Currier, S. Ahmed Athar, Saket Girotra, Calvin Leung, Thomas J. Helton, Ajay Agarwal, Mladen I. Vidovich, Mary E. Plomondon, Stephen W. Waldo, Kelly A. Aschbrenner, Virginia McKay, A. James O'Malley, Jeremiah R. Brown

“…The main outcome was AKI within 7 days of cardiac catheterization among all participants and those with preexisting chronic kidney disease. In addition, survey and focused interview data were collected to understand barriers and facilitators to sustaining AKI improvements. …”
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Construction and validation of renal cell carcinoma tumor cell differentiation-related prognostic classification (RCC-TCDC): an integrated bioinformatic analysis and clinical study by Yifan Liu, Keqin Dong, Yuntao Yao, Bingnan Lu, Lei Wang, Guo Ji, Haoyu Zhang, Zihui Zhao, Xinyue Yang, Runzhi Huang, Wang Zhou, Xiuwu Pan, Xingang Cui

“…In addition, we performed correlation analysis and Cmap algorithm for regulatory network establishment and candidate inhibitor prediction. …”
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Generating synthetic brain PET images of synaptic density based on MR T1 images using deep learning by Xinyuan Zheng, Patrick Worhunsky, Qiong Liu, Xueqi Guo, Xiongchao Chen, Heng Sun, Jiazhen Zhang, Takuya Toyonaga, Adam P. Mecca, Ryan S. O’Dell, Christopher H. van Dyck, Gustavo A. Angarita, Kelly Cosgrove, Deepak D’Souza, David Matuskey, Irina Esterlis, Richard E. Carson, Rajiv Radhakrishnan, Chi Liu

“…We therefore aim to generate synthetic [11C]UCB-J PET images based on MRI in this study. Methods We implemented a convolution-based 3D encoder-decoder to predict [11C]UCB-J SV2A PET images. …”
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Detection of hypervirulent Klebsiella pneumoniae (hvKp) strains directly from spiked blood cultures using a commercial Loop-Mediated isothermal amplification (LAMP) assay by Domingo Fernández Vecilla, Jorge Rodríguez Grande, Nuria Fraile Valcárcel, Zaira Moure García, Sergio García Fernández, María Siller Ruiz, María Pía Roiz Mesones, José Luis Díaz de Tuesta del Arco, Mikel Joseba Urrutikoetxea Gutiérrez, María Catalina Lomoro, María Carmen Fariñas, Alain Ocampo-Sosa

“…However, limitations in the Kleborate scoring system indicate that additional virulence biomarkers may be needed to improve the accuracy of hvKp classification.…”
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Assessing the effectiveness of travel control measures in preventing imported COVID-19 cases reveals the critical role of travel volume by Mingwei Li, Karen A. Grépin, Ru Zhang, Benjamin J. Cowling, Bingyi Yang

“…We compared the number of prevented infections under the implemented measures to a scenario where no measures were taken. …”
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