Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza by Zhaoyuan Gong, Qianzi Che, Mingzhi Hu, Tian Song, Lin Chen, Haili Zhang, Ning Liang, Huizhen Li, Guozhen Zhao, Lijiao Yan, Xuefei Zhang, Bin Liu, Jing Guo, Nannan Shi

“…The high risk of viral variability, drug resistance, and drug development leads to a scarcity of therapeutic drugs. …”
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Adaptive Stochastic Approach for Evaluating Service Level Using a (SIM-ESL) Module Developed for Optimizing Product Availability and Order Accuracy by Aufy Samah A., Jabbar Rasha, Shiaa Waad Q.

“…It is structured with two models are: Evaluation Dynamic Maximum Economic Order Quantity (EDEOQ) model developed Artificial Neural Network (ANN) to evaluate the optimum inventory level of finished goods as a function of product varied demand and lead time. The second one, Variability Between-Among Dynamic Economic Order Quantity (VB-ADEOQ) is modeled a fuzzy logic to estimate the performance measures (AOP and AOO) that make sure the required order is being processed and delivered on time. …”
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ITER NBI operational window and power availability constraints due to shine-through losses by P. Vincenzi, M. Schneider, P. Veltri, J.F. Artaud, A. Loarte, S. Nicolici, C. Poggi, A.R. Polevoi, A. Snicker

“…We then present a new heuristic formula which permits the calculation of the ST fraction and the minimum plasma density that permits ITER NBI operations as a function of global variables. This allows for establishing operational limits for Hydrogen and Deuterium NBI in Hydrogen, Deuterium, and Deuterium–Tritium plasmas. …”
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Hybrid Approach of Finite Element Method, Kigring Metamodel, and Multiobjective Genetic Algorithm for Computational Optimization of a Flexure Elbow Joint for Upper-Limb Assistive D... by Duc Nam Nguyen, Thanh-Phong Dao, Ngoc Le Chau, Van Anh Dang

“…The optimization problem considers three design variables and two objective functions. An efficient hybrid optimization approach of central composite design (CDD), finite element method (FEM), Kigring metamodel, and multiobjective genetic algorithm (MOGA) is developed. …”
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Three Decades of Land Cover Dynamics in a Boreal Coastal Basin: A Multisensor Spectral Index and Machine Learning Approach Using Landsat Data and GB-SAR Data by Jinsong Zhang, Bochi Zou, Yifei Yuan, Asad Khan, Muhammad Bilawal Junaid, Qaiser Abbas, Rana Muhammad Zulqarnain, Nazih Y. Rebouh, Olga D. Kucher, Hassan Alzahrani

“…Boreal coastal habitats, with their complex hydrological, ecological, and geological functions, play a pivotal role in regulating regional climate, supporting biodiversity, and sustaining local communities. …”
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Development and validation of a novel prediction model for osteoporosis: from serotonin to fat-soluble vitamins by Jinpeng Wang, Lianfeng Shan, Jing Hang, Hongyang Li, Yan Meng, Wenhai Cao, Chunjian Gu, Jinna Dai, Lin Tao

“…Stepwise discriminant analysis was performed to identify efficient predictors for osteoporosis. The prediction model was developed based on Bayes and Fisher’s discriminant functions, and validated via leave-one-out cross-validation. …”
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The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review by Stanisław Dudek, Weronika Koziak, Aleksandra Bętkowska, Agata Kornacka, Kamila Szostak, Rafał Tomaka, Michalina Makieła, Wojciech Dudek, Anna Byra

“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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Steps to Avoid Falls in the Elderly – a TECHnology Enhanced Intervention (SAFE-TECH) study: randomized controlled trial protocol for a community-based, multi-component fall prevent... by Wei Xuan Lai, Vanessa Koh, Jing Wen Goh, Kok Yang Tan, Kai Zhe Tan, Sai G. S. Pai, William R. Taylor, Abhijit Visaria, Navrag B. Singh, Angelique W. M. Chan, David B. Matchar

“…In previous research, exercise interventions have been effective in improving functional outcomes and reducing falls for a broad group of older adults. …”
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Structural Parameter Identification Using Multi-Objective Modified Directional Bat Algorithm by LIU Li-jun, LIN Ying-hai, SU Yong-hui, LEI Ying

“…The algorithm began with the initialization of optimization variables， constraints， Pareto front size， and key parameters such as frequency， loudness， and pulse rates. …”
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Good Governance and Seigniorage in a Selected OPEC Countries and Iran by ALI Rashid Shamkhal, Kambiz Paykarjou, beitollah Akbari Moghaddam

“…The research results did not indicate a negative relationship between the variables of "political stability and absence of violence/terrorism" and "government effectiveness." …”
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Perinatal bisphenol A exposure impairs gut microbial colonization: Implications for offspring obesity and neurodevelopment by Ana López-Moreno, Alfonso Torres-Sánchez, Antonio Suárez, Alicia Ruiz-Rodríguez, Margarita Aguilera

“…Toxicological approaches in animal models have revealed complex effects, using variable doses of BPA, on reproduction, development, obesity, immune function, metabolic and systemic toxicity. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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Modeling of project activities for UAV modernization to conduct swarm drone attack missions by Oleg Fedorovych, Leonid Malieiev, Oleksii Hubka, Andrei Popov

“…These qualitative evaluations, represented as linguistic variables, were processed using the lexicographic ordering of alternatives to identify the most reasonable option for implementation. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Actigraphy was used to evaluate sleep and circadian rhythm, while HRV was monitored for 24 hours to assess autonomic nerve function. Nonparametric indicators were calculated to quantify the active-rest patterns, including interdaily stability, intradaily variability, the most active 10 consecutive hours (M10), the least active 5 consecutive hours (L5), the relative amplitude, and the actigraphic dichotomy index. …”
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Immunological Avalanches in Renal Immune Diseases by Davide Viggiano, Pietro Iulianiello, Antonio Mancini, Candida Iacuzzo, Luca Apicella, Renata Angela Di Pietro, Sarah Hamzeh, Giovanna Cacciola, Eugenio Lippiello, Andrea Gigliotti, Carmine Secondulfo, Giancarlo Bilancio, Giuseppe Gigliotti

“…In a preliminary study on kidney transplant, all measured variables showed temporal instability. Proteinuria exhibited precise log–log linearity in power law analysis, confirming near-critical-point system behavior. …”
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On the Nonlinear Forced Vibration of the Magnetostrictive Laminated Beam in a Complex Environment by Nicolae Herisanu, Bogdan Marinca, Vasile Marinca

“…The nonlinear differential equations were studied using an original, explicit, and very efficient technique, namely the optimal auxiliary functions method (OAFM). …”
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Enhancing epidemic preparedness: a data-driven system for managing respiratory infections by Moslem Sarani, Katayoun Jahangiri, Manoochehr Karami, Mohammadreza Honarvar

“…Results Key data categories include individual-level variables, such as age, symptoms, and vaccination records, alongside population-level metrics like infection rates and regional vaccination coverage enabling functionalities such as identifying high-risk individuals, tracking infection dynamics, and optimizing resource allocation. …”
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Prediction of suicidal attempts among Chinese adolescents with mood disorders: a clinical study using a machine learning approach by Jianbing Li, Yinqiu Zhao, Chi Yang, Wenqing Li, Zhihao Huang, Changhe Fan

“…However, there is a need for studies of accurate and efficient SA models specifically for use in adolescents with mood disorders due to a lack of existing research integrating risk variables when predicting clinical SA. …”
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Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…Using Cox hazard analysis with these variables, a multivariate model was established to stratify patient overall survival (OS). …”
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Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study by Nurgeldi Manap, Nagmet Mursalov, Mukhtar Abilmazhinov

“…Exclusion criteria: other operative approaches to pelvic bones and patients under 18 years of age. 21 patients underwent surgery with the use of modified Stoppa approach (group A) and 10 surgeries were performed using the ilioinguinal approach (group B). Efficiency was evaluated by comparison of duration of surgical procedures, amount of blood lossbetween groups, size of skin incision, quality of reduction and functional outcomes. …”
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