Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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Jointed rock slope stability evaluation based on PEM-JFEM method by XIAO Shu, WU Shun-chuan, GAO Yong-tao, HAN Guang, ZHOU Yu, CHENG Ai-ping

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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries by Keith Mitchell, Samuel Hunter, Lutz Froenicke, Karl Murray, Matthew Settles, James S. Trimmer

“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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Comparing the Effect of Beractant (Beraksurf™) with That of Poractant Alfa (Curosurf®) on the Need for Intermittent Positive Pressure Ventilation in Neonatal Respiratory Distress S... by Yosra Khazani, Sirous Fathi Manesh, Elnaz Shaseb, Parvin Sarbakhsh

“…Performing appropriate adjusted analysis leads to a more interpretable and efficient estimation of treatment effects. Semiparametric adjustment approach modifies the estimating equations solved by the marginal treatment effect estimator by adding an augmentation function, which makes use of the baseline covariates and estimate the unbiased marginal treatment effect with improved precision. …”
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REALITIES AND EFFECTIVENESS OF THE UKRAINIAN BANKING SYSTEM by Maryna Korol, Olena Bazhenova, Ihor Korol, Grygoriy Starchenko, Volodymyr Bazhenov, Oksana Banna

“…In addition, during the year after the crisis, the volume of deposits in the banking system is demonstrating a decrease. Other variables do not show any response to the crisis. …”
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Grid-connected PV inverter system control optimization using Grey Wolf optimized PID controller by Monika Gupta, P. M. Tiwari, R. K. Viral, Ashish Shrivastava, Basem Abu Zneid, Iryna Hunko

“…Conventional controllers such as P and PI are widely used in PV applications due to their simplicity, but they exhibit notable limitations in dynamic environments, including increased Total Harmonic Distortion (THD), slower transient response, and poor voltage regulation—particularly under variable irradiance conditions. The proposed GWO-PID method overcomes these limitations by leveraging the GWO algorithm’s global search capability to dynamically optimize the PID gains (Kp, Ki, Kd) based on a composite fitness function that minimizes Mean Squared Error (MSE) and THD. …”
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Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

“…Resting-state fMRI data were collected before and after treatment to assess functional connectivity within the predefined 35-region AVH-related network. small-worldness (σ), normalized clustering coefficient (γ), and normalized characteristic path length (λ), as well as functional segregation (clustering coefficient [Cp], local efficiency [El]) and functional integration (global efficiency [Eg], characteristic path length [Lp])—were analyzed before and after rTMS. …”
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Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews by Cindy E. Frias, Nimesh Samarasinghe, Cecilia Cuzco, Jaseem Koorankot, Andrés de Juan, Husameldin Mohamed Ali Rudwan, Hanan F. Abdul Rahim, Adela Zabalegui, Iain Tulley, Sanaa T. Al-Harahsheh, Mona Shaheen S. T. Al-Homaiddi, Meredith Fendt-Newlin, Jim Campbell

“…Sixteen studies reported two types of mental health and well-being interventions: individual-level interventions and organizational-level interventions with specific impact on mental health and work environment variables. No specific policy interventions were found. …”
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Factors Influencing The Use of QRIS in Digital Transactions by Fadhil Muhammad, Arif Imam Suroso, Setiadi Djohar

“…Purpose: The purpose of QRIS is to expand the efficient acceptance of non-cash payments, focusing on traditional mass economic functions (such as traditional markets and MSMEs). …”
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An Empirical Analysis of Herding Behavior in the Stock Market: Evidence from Various Economic and Social Conditions in Iran by Majid Aghaei

“…This approach models the response of the dependent variable to the independent variable at various quantiles, denoted as "τ," making it an effective tool for analyzing non-normal distributions. …”
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Optimisation of the performance and structure of soluble ball seat metal sealing rings based on response surface by CHEN Zhen, RAN Qingjie, CHEN Nengpeng, WANG Qiaomu

“…Horizontal well fracturing technology, as a core tool for efficient development of tight oil and gas reservoirs, is of strategic significance for enhancing the recovery rate of unconventional oil and gas resources. …”
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Protein expression profiling identifies a prognostic model for ovarian cancer by Luyang Xiong, Jiahong Tan, Yuchen Feng, Daoqi Wang, Xudong Liu, Yun Feng, Shusheng Li

“…Patients with complete information concerning protein expression, survival, and clinical variables were included. A risk model was then constructed by performing multiple Cox regression analysis. …”
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Investigating Whether AI Will Replace Human Physicians and Understanding the Interplay of the Source of Consultation, Health-Related Stigma, and Explanations of Diagnoses on Patien... by Weiqi Guo, Yang Chen

“…The main effects and interaction effects of the variables were examined on individuals’ functional, relational, and emotional evaluations of the medical consultation. …”
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A Combined Approach to Solving Applied Metal Forming Problems by Matvej Baldin, Nikita Kondratev, Peter Trusov, Kirill Ostapovich

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fNIRS neurofeedback facilitates emotion regulation: Exploring individual differences over the ventrolateral prefrontal cortex by Yiwei Li, Sijin Li, Hua Li, Yuyao Tang, Dandan Zhang

“…Participants in the experimental group underwent VLPFCNF training over eight sessions across two consecutive days, while those in the sham group received random signals from functional near-infrared spectroscopy (fNIRS). To investigate individual variability, participants in the experimental group were further categorized as high or low-efficacy groups based on their training efficiency, determined by the regression slope of VLPFC activity over the sessions. …”
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Effects of electron beam irradiation on microbial loads, physicochemical properties, stability of active ingredients, and antioxidant activity in Angelica sinensis Radix by Yunxia Hu, Haijun Wang, Zhijun Xin, Wensheng Gou, Zhuanzi Wang, Xiao Liu, Xihong Lu, Aimei Yang, Xuehu Li, Libin Zhou

“…Orthogonal partial least squares discriminant analysis (OPLS-DA) coupled with variable importance in projection (VIP) scores identified potential biomarkers for discriminating irradiation doses. …”
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Copula Modeling and Uncertainty Propagation in Field‐Scale Simulation of CO2 Fault Leakage by Per Pettersson, Eirik Keilegavlen, Tor Harald Sandve, Sarah E. Gasda, Sebastian Krumscheid

“…The uncertainty in upscaled flow functions and other uncertain parameters are efficiently propagated to leakage estimates using numerical reservoir simulation of a two‐phase system of CO2 and brine. …”
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Neighborhood competition improves biomass estimation for Scots pine (Pinus sylvestris L.) but not Pyrenean oak (Quercus pyrenaica Willd.) in young mixed forest stands by Eric Cudjoe, Ricardo Ruiz-Peinado, Hans Pretzsch, Shamim Ahmed, Felipe Bravo

“…Therefore, accurate biomass estimation is essential for understanding ecosystem functioning and informing forest management strategies to mitigate climate change. …”
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Design and evaluation of BOOGIE: a collector for the analysis of cloud composition and processes by M. Vaitilingom, M. Vaitilingom, C. Bernard, M. Ribeiro, C. Verhaege, C. Verhaege, C. Gourbeyre, C. Berthod, A. Bianco, L. Deguillaume, L. Deguillaume

“…<p>In situ cloud studies are fundamental to study the variability in cloud chemical and biological composition as a function of environmental conditions and assess their potential for transforming chemical compounds. …”
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Renal Biopsy Pathological Tissue Segmentation: A Comprehensive Review and Experimental Analysis by Yan Liu, Taiping Wang, Xinxin He, Wei Wang, Qiang He, Juan Jin

“…Traditional renal biopsy pathological analysis relies heavily on subjective judgment by pathologists, which is time-consuming and susceptible to inter-observer variability, especially in segmenting glomeruli, renal tubules, and renal vessels. …”
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