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IgG1 versus IgG3: influence of antibody-specificity and allotypic variance on virus neutralization efficacy
Published 2024-10-01“…P5C3 and H4-IgG1 mAbs were subclass-switched to IgG3 formats, designed for efficient production and increased PK values, carrying three allotypic variations, referred to as -WT, -H, and -KVH. …”
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143
An Explnation of Entrepreneurship Drivers and Rural Competitiveness Functions
Published 2020-12-01Get full text
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144
Copula Modeling and Uncertainty Propagation in Field‐Scale Simulation of CO2 Fault Leakage
Published 2025-01-01“…The uncertainty in upscaled flow functions and other uncertain parameters are efficiently propagated to leakage estimates using numerical reservoir simulation of a two‐phase system of CO2 and brine. …”
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145
Clinical characteristics of 30 children with severe acute SARS‐CoV‐2 infection
Published 2024-12-01Get full text
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146
CoCEC: An Automatic Combinational Circuit Equivalence Checker Based on the Interactive Theorem Prover
Published 2021-01-01“…It automatically proves, in few seconds, the equivalence of circuits with as many as 45 variables (3.5 × 1013 states). CoCEC has a mathematical foundation, and it is reliable, quick, and easy to use. …”
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147
Optimization of solid-state fermentation technology of functional Monascus
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148
Integrating multiple “omics” analysis for plant metabolites and their functions
Published 2013-05-01“…Future research will be mainly focus on the “key” variable site that decides the single biosynthetic step. …”
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149
Cation disordering in ankerite as a function of Fe content
Published 2025-08-01“…The present study investigates the effect of Fe content in ankerite, Ca(Fe<span class="inline-formula"><sub><i>x</i></sub></span>Mg<span class="inline-formula"><sub>1−<i>x</i></sub></span>)(CO<span class="inline-formula"><sub>3</sub></span>)<span class="inline-formula"><sub>2</sub></span> (0 <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M5" display="inline" overflow="scroll" dspmath="mathml"><mrow><mo>≤</mo><mi>x</mi><mo>≥</mo><mn mathvariant="normal">0.7</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="47pt" height="11pt" class="svg-formula" dspmath="mathimg" md5hash="7e9f34f066117e7703372b3d8982d666"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-37-577-2025-ie00001.svg" width="47pt" height="11pt" src="ejm-37-577-2025-ie00001.png"/></svg:svg></span></span>, <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M6" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>R</mi><mover accent="true"><mn mathvariant="normal">3</mn><mo mathvariant="normal">¯</mo></mover></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="17pt" height="12pt" class="svg-formula" dspmath="mathimg" md5hash="859aee91089780fda1e5e9c75281293c"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-37-577-2025-ie00002.svg" width="17pt" height="12pt" src="ejm-37-577-2025-ie00002.png"/></svg:svg></span></span> space group), on the distribution of cations in its crystal structure as a function of temperature. …”
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150
Clinical relevance of loss-of-function mutations of NEMO/IKBKG
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151
Synergistic fermentation of vitamin B2 (riboflavin) bio-enriched soy milk: optimization and techno-functional characterization of next generation functional vegan foods
Published 2025-01-01“…Additionally, techno-functional characterization, including rheology and texture profile analysis, showed that enhanced protease activity of co-cultured LAB improved protein hydrolysis (6259 nm), positively impacting the water holding capacity (WHC) and overall acceptability of the fermented soymilk. …”
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The exacerbating effects of stable pulmonary tuberculosis on the deterioration of inflammatory response, coagulation function, and pulmonary function in COPD: A propensity score-ma...
Published 2025-08-01“…Chronic obstructive pulmonary disease (COPD) and tuberculosis pose significant public health challenges, particularly in tuberculosis-endemic developing regions where their co-prevalence may exacerbate the disease burden of chronic airflow obstruction. …”
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Co-speech gestures influence the magnitude and stability of articulatory movements: evidence for coupling-based enhancement
Published 2025-01-01“…What functional principles underlie this relationship? Here, we examine how the production of co-speech manual gestures influences spatiotemporal patterns of the oral articulators during speech production. …”
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Co-Simulation Model for Determination of Optimal Active Power Filters Settings in Low-Voltage Network
Published 2025-01-01“…This paper, along with a detailed analysis of the literature, provides an overview of different views on the problems of optimal allocation of active filters and emphasizes the importance that the problem of optimal allocation of active filters should be based on the variability of the harmonic spectrum as a function of time. …”
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156
Further Refinements of Jensen’s Type Inequalities for the Function Defined on the Rectangle
Published 2013-01-01“…We give refinement of Jensen’s type inequalities given by Bakula and Pečarić (2006) for the co-ordinate convex function. Also we establish improvement of Jensen’s inequality for the convex function of two variables.…”
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Synthesis of combinational circuits by means of bi-decomposition of Boolean functions
Published 2022-03-01“…Each of those bi-cliques defines a Boolean function whose arguments are the variables assigned to it. …”
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Uncovering a conserved vulnerability site in SARS‐CoV‐2 by a human antibody
Published 2021-11-01“…The epitope coincides with a predicted “ideal” vulnerability site with high functional and structural constraints. Mutation of the residues of the conserved epitope variably affects FD20‐binding but confers little or no resistance to neutralization. …”
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Differential impact of TIM-3 ligands on NK cell function
Published 2025-01-01“…An effective TIM-3-targeting therapy should account for multiple biological factors, including the disease setting, the specific cell types involved and their varying sensitivities to the four putative TIM-3 ligands (galectin-9, phosphatidylserine, high mobility group protein B1 and carcinoembryonic antigen cell adhesion molecule 1), each of which engages a unique binding site on the receptor’s variable immunoglobulin domain. The primary objectives of this study were to assess the prevalence and function of TIM-3+ natural killer (NK) cells in patients with head and neck squamous cell carcinoma (HNSCC), determine whether the four TIM-3 ligands differentially affect TIM-3+ NK cell functions, identify the most immunosuppressive ligand, and evaluate whether targeting ligand-mediated TIM-3 signaling enhances NK cell effector functions.Methods Single-cell RNA sequencing and flow cytometry were used to study the prevalence, phenotypes and function of TIM-3+ NK cells in HNSCC patient tumors and blood. …”
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