Methicillin‐resistant Staphylococcus aureus and Pseudomonas aeruginosa community acquired pneumonia: Prevalence and locally derived risk factors in a single hospital system by Bradley W. Frazee, Amarinder Singh, Matt Labreche, Partow Imani, Kevin Ha, Jonathan Furszyfer Del Rio, Eugene Kreys, Robert Mccabe

“…Inclusion criteria included an ED admission diagnosis of pneumonia or sepsis, fever or hypothermia, leukocytosis or leukopenia, and consistent chest imaging result. SARS‐CoV‐2‐positive cases were excluded. We abstracted variables historically associated with P. aeruginosa and MRSA. …”
Get full text

Comparative chromato-mass spectrometric study of tinctures based on Echinacea purpurea (L.) Moench by Y. I. Kornievskiy, D. Yu. Skoryna, V. H. Korniievska, N. V. Kandybei

“…An urgent problem today is the spread of secondary immunodeficiencies associated with increased stress, urbanization, and negative changes in the environment that lead to impaired immune function. Herbal remedies are milder, less likely to become addictive and have side effects, and are long-lasting. …”
Get full text

Abstract 020: Undulating Flow Velocities as an Induced Test of Autoregulation After Thrombectomy for Acute Ischemic Stroke by Aya Mikkawi, Qasem N Alshaer, Mahmoud Mohammaden, Diogo Haussen, Aaron Anderson

“…TCD was repeated after EVT, and the previously seen undulating pattern was lost with significantly reduced variability on the right MCA compared to the contralateral side (figure 1E – Post‐EVT). …”
Get full text

Alternative splicing induces sample-level variation in gene–gene correlations by Yihao Lu, Brandon L. Pierce, Pei Wang, Fan Yang, Lin S. Chen

“…Conclusions We showed that splicing variation of a gene may interact with TE of the gene and affect the TE of co-expressed genes, resulting in substantial tissue-specific inter-sample variability in gene–gene correlation effects. …”
Get full text

Life cycle greenhouse gas emissions of diesel oil and zero-emission trucks: Systematic review of status and perspectives by Gaia Gentilucci, Antonella Accardo, Ezio Spessa

“…Quantitatively, the analysis highlights a significant variability of the carbon footprint results, ranging between 431–1780 tons CO2eq for diesel ICEVs, 175–1626 tons CO2eq for battery electric vehicles, 366–2944 tons CO2eq for fuel cell electric vehicles. …”
Get full text

Sustainable forest management: success and challenges in Ethiopia by Rusha Begna Wakweya

“…The outcomes of local-level forest governance depend on the quality, efficiency, and effectiveness of local policymaking and decision-making processes, as well as how power and authority are exercised locally. …”
Get full text

Imidacloprid decreases energy production in the hemolymph and fat body of western honeybees even though, in sublethal doses, it increased the values of six of the nine compounds in... by Jerzy Paleolog, Jerzy Wilde, Marek Gancarz, Aneta Strachecka

“…<h4>Results</h4>the assayed compounds had higher values in the fat body than in the hemolymph, whereas their variability was higher in the hemolymph. The pattern of response to IM was the same in both tissues, but markedly differed between IM-200 and IM-5. …”
Get full text

Multi-omics identification of a polyamine metabolism related signature for hepatocellular carcinoma and revealing tumor microenvironment characteristics by Yuexi Yu, Huiru Liu, Kaipeng Liu, Meiqi Zhao, Yiyan Zhang, Runci Jiang, Fengmei Wang

“…Additionally, we developed a prognostic nomogram model by integrating PMRS with clinical variables. To explore immune treatment sensitivity, we assessed tumor mutation burden (TMB), tumor immune dysfunction and exclusion (TIDE) score, mutation frequency, and immune checkpoint genes expression. …”
Get full text

Cognitive impact and brain structural changes in long COVID patients: a cross-sectional MRI study two years post infection in a cohort from Argentina by Sol A. Cataldo, Andrea Micciulli, Laura Margulis, Melina Cibeyra, Sabrina Defeo, Silvina G. Horovitz, Analía Martino, Raul Melano, Milagros Mena, Francisco Parisi, Diego Santoro, Florencia Sarmiento, Martin A. Belzunce

“…Abstract Objective Long COVID is a condition characterised by persistent symptoms after a SARS-CoV-2 infection, with neurological manifestations being particularly frequent. …”
Get full text

ELM‐Wet: Inclusion of a Wet‐Landunit With Sub‐Grid Representation of Eco‐Hydrological Patches and Hydrological Forcing Improves Methane Emission Estimations in the E3SM Land Model... by Theresia Yazbeck, Gil Bohrer, Madeline E. Scyphers, Justine E. C. Missik, Oleksandr Shchehlov, Eric J. Ward, Sergio L. Merino, Robert Bordelon, Diana Taj, Jorge A. Villa, Kelly Wrighton, Qing Zhu, William J. Riley

“…Our results show that ELM‐Wet reduces the model's CH4 emission root mean squared error by up to 33% and is able to represent inter‐daily CO2 and CH4 flux variability across the wetland's eco‐hydrological patches, including during periods of extreme dry or wet conditions.…”
Get full text

Pulmonary vein isolation does not alter cardiovascular afferent autonomic reflexes in atrial fibrillation by Varun Malik, Adrian D. Elliott, Gijo Thomas, Bradley Pitman, John L. Fitzgerald, Glenn D. Young, Leonard F. Arnolda, Dennis H. Lau, Prashanthan Sanders

“…Mean age was 64 ± 3 years (78% male); BMI 28 ± 1 kg/m2; LA size 37 ± 2 mL/m2; and left ventricular function 65 ± 3%. Despite alterations in heart rate variability (HRV), there was no difference in IHR, Valsalva, or LBNP responses pre‐ versus post‐PVI. …”
Get full text

Una mirada al origen y las propiedades de los suelos magnésicos en el Valle del Cauca-Colombia by Garcia O. A., Malagón C. D., Madero E

Get full text

Self-silencing adenovirus enables precise infectious titration of recombinant adeno-associated viral vectors by Chloé Fustinoni, Xiang Liu, Zhi Chen, Ryan Cawood, Weimin Valenti, Maria I. Patrício, Weiheng Su

“…The industry standard method for rAAV titration is the 50% tissue culture infectious dose (TCID50) assay using HeLa-based cell lines that stably encode the rep and cap genes from AAV serotype 2. Co-infection with wild-type (WT) adenoviruses provides the helper functions for expression of these genes, and the use of quantitative PCR (qPCR)/droplet digital PCR (ddPCR) serves as the endpoint method for the detection of infectious events. …”
Get full text

An integrated machine learning model of transcriptomic genes in multi-center chronic obstructive pulmonary disease reveals the causal role of TIMP4 in airway epithelial cell by Erkang Yi, Haiqing Li, Yu Liu, Qingyang Li, Chengshu Xie, Ruining Sun, Fan Wu, Zhishan Deng, Kunning Zhou, Hairong Wang, Xinru Ran, Yumin Zhou, Pixin Ran

“…Identifying a core set of genes consistently involved in COPD pathogenesis, independent of patient variability, is essential. Methods We integrated lung tissue sequencing data from patients with COPD across two centers. …”
Get full text

Development of an Agrobacterium tumefaciens-mediated transformation system for somatic embryos and transcriptome analysis of LcMYB1’s inhibitory effect on somatic embryogenesis in... by Yaqi Qin, Bo Zhang, Xueliang Luo, Shiqian Wang, Jiaxin Fu, Zhike Zhang, Yonghua Qin, Jietang Zhao, Guibing Hu

Get full text

Model supports asymmetric regulation across the intercellular junction for collective cell polarization. by Katherine Levandosky, Calina Copos

“…Symmetry breaking, which is ubiquitous in biological cells, functionally enables directed cell movement and organized embryogenesis. …”
Get full text

The DOE E3SM version 2.1: overview and assessment of the impacts of parameterized ocean submesoscales by K. M. Smith, A. M. Barthel, L. M. Conlon, L. P. Van Roekel, A. Bartoletti, J.-C. Golaz, C. Zhang, C. B. Begeman, J. J. Benedict, G. Bisht, Y. Feng, W. Hannah, B. E. Harrop, N. Jeffery, W. Lin, P.-L. Ma, M. E. Maltrud, M. R. Petersen, B. Singh, Q. Tang, T. Tesfa, J. D. Wolfe, S. Xie, X. Zheng, K. Balaguru, O. Garuba, P. Gleckler, A. Hu, J. Lee, B. Moore-Maley, A. C. Ordoñez

Get full text

In vivo therapeutic effect of combination treatment with metformin and Scutellaria baicalensis on maintaining bile acid homeostasis. by Kyungsun Han, Shambhunath Bose, Jing-Hua Wang, Soo-Kyoung Lim, Young-Won Chin, Young-Mi Kim, Han-Seok Choi, Hojun Kim

“…Although there were no significant changes in BSH-active gut microbiota due to high variability, functional prediction with 16S sequences showed increased primary and secondary bile acid biosynthesis in the combination treatment group. …”
Get full text

From rings to regions: modeling and mapping climate-driven timber production zones for Cyclocarya paliurus by integrating niche models and growth traits by Zijie Zhang, Zijie Zhang, Zhengyang Ye, Xulan Shang, Xulan Shang, Wanxia Yang, Wanxia Yang, Tongli Wang, Shengzuo Fang, Shengzuo Fang

Get full text

A Preliminary Investigation into Heavy Metal Tolerance in <i>Pseudomonas</i> Isolates: Does the Isolation Site Have an Effect? by Alessandro De Santis, Antonio Bevilacqua, Angela Racioppo, Barbara Speranza, Maria Rosaria Corbo, Clelia Altieri, Milena Sinigaglia

“…A subset of isolates showed co-tolerance to elevated temperatures and heavy metals. …”
Get full text