Clinical characterization of Collagen XII‐related disease caused by biallelic COL12A1 variants by Riley M. McCarty, Dimah Saade, Pinki Munot, Chamindra G. Laverty, Hailey Pinz, Yaqun Zou, Meghan McAnally, Pomi Yun, Cuixia Tian, Ying Hu, Lucy Feng, Rahul Phadke, Sophia Ceulemans, Pilar Magoulas, Andrew J. Skalsky, Jennifer R. Friedman, Stephen R. Braddock, Sarah B. Neuhaus, Denise M. Malicki, Matthew N. Bainbridge, Shareef Nahas, David P. Dimmock, Stephen F. Kingsmore, Timothy E. Lotze, A. Reghan Foley, Francesco Muntoni, Volker Straub, Sandra Donkervoort, Carsten G. Bönnemann

“…Results All patients presented with a consistent constellation of congenital onset clinical features: hypotonia, dysmorphic features, most notably gingival hypertrophy, prominent distal joint hyperlaxity, with co‐occurring contractures of large joints, and variable muscle involvement, evident both clinically and on muscle imaging. …”
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Neutral Mode Dominates the Forced Global and Regional Surface Temperature Response in the Past and Future by Fukai Liu, Jian Lu, L. Ruby Leung

“…Abstract Using a large suite of Green's function perturbation experiments, we construct the emergent dynamical operator for surface temperature and extract the most excitable mode. …”
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Deep-learning-based extraction of circle of Willis topology with anatomical priors by Dieuwertje Alblas, Iris N. Vos, Micha M. Lipplaa, Christoph Brune, Irene C. van der Schaaf, Mireille R. E. Velthuis, Birgitta K. Velthuis, Hugo J. Kuijf, Ynte M. Ruigrok, Jelmer M. Wolterink

“…Abstract The circle of Willis (CoW) is a circular arrangement of arteries in the human brain, exhibiting significant anatomical variability. …”
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Oil price shocks and human capital channels in Nigeria by Olabisi Rasheedat Oladipo, Abiola John Asaleye, Ademola Andrew Onabote, Damilola Felix Eluyela, Rotimi Ayoade Ogunjumo, Joseph Olufemi Ogunjobi, Olufemi Adebayo Oladipo, Stephen Adesina Ibitowa

“…While many studies have investigated the relationship between oil price volatility and human capital development, few have examined how this relationship impacts both basic and advanced human capital channels in developing economies; this study addresses that gap by using a Structural Vector Auto Regression (SVAR) approach to investigate how oil price shocks influence human capital channels. Co-integration tests reveal significant long-term relationships among the variables. …”
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A novel method for calculating number buildup factor in gamma-ray transmission measurements using narrow beam geometry by Chuong Huynh Dinh, Trang Le Thi Ngoc, Linh Nguyen Thi Truc, Nguyen Vo Hoang, Thanh Tran Thien

“…Furthermore, the slope of these linear relationships can be expressed as a product of mass density and a cubic polynomial function of the atomic number. Based on these findings, we developed a fitting formula to calculate the number buildup factor using the input variables of sample thickness, mass density, and atomic number. …”
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Modeling the Short-Term Effect of Traffic and Meteorology on Air Pollution in Turin with Generalized Additive Models by Pancrazio Bertaccini, Vanja Dukic, Rosaria Ignaccolo

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Transcriptome analysis to decipher the molecular underpinnings of response to treatment in systemic lupus erythematosus by Dimitrios T Boumpas, Antonis Fanouriakis, George Bertsias, Dionysis Nikolopoulos, Aggelos Banos, Anastasia Filia, Antigone Pieta, Sofia Flouda, Katerina Chavatza, Panagiotis Garantziotis, Spyridon Katechis, Noemin Kapsala, George Sentis, Georgia Savina Moysidou, Nikos Malissovas

“…Objective Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterised by variable treatment responses. We investigated the transcriptional landscape associated with treatment response and resistance in SLE.Methods Blood was collected from 92 active patients with SLE at baseline and after 6 months (n=32 paired samples) of treatment with cyclophosphamide (n=40), rituximab (n=20), belimumab (n=23), mycophenolate mofetil (n=8) or azathioprine (n=1) and was subjected to RNA sequencing. …”
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Divergent altitudinal patterns of arbuscular and ectomycorrhizal fungal communities in a mid-subtropical mountain ecosystem by Taotao Wei, Huiguang Zhang, Shunfen Wang, Chunping Wu, Tieyao Tu, Yonglong Wang, Xin Qian

“…Among the examined factors, soil properties emerged as the predominant driver of altitudinal variations in ecosystem multifunctionality, followed by AMF communities and climatic variables. These findings provide critical insights into the ecological functions and environmental adaptations of mycorrhizal fungi, advancing our understanding of their responses to environmental changes in mountain ecosystems and informing evidence-based conservation strategies.…”
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IGF2BP3 promotes autophagy-mediated TNBC metastasis via m6A-dependent, cap-independent c-Met translation by Zi-Wen Wang, Yi-Han Li, Meng-Yuan Cai, Xu Zhang, Ruo-Xi Xu, Hai-Yan Yang, Yu-Zhou Huang, Liang Shi, Ji-Fu Wei, Qiang Ding

“…The cooperation of epigenetic modifications and metabolic adaptations enables tumor cells to dynamically adjust for survival in variable environments, which is crucial for tumor metastasis and worth exploring in depth. …”
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Serum proteomic correlates of mental health symptoms in a representative UK population sample by Anna Dearman, Yanchun Bao, Leonard Schalkwyk, Meena Kumari

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Using preprocessed datasets to construct and interpret multiclass identification models by Cong Wang, Yufeng Fu, Ran Wan, Le Zhao, Hongbo Wang, Junwei Guo, Qiang Liu, Shan Li, Shengtao Ma, Zhicai Wang, Wei Huang, Huimin Liu, Song Yang, Cong Nie

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An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy by Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan

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Dataset on Environmental Parameters and Greenhouse Gases in Port and Harbor Seawaters of Jeju Island, Korea by Jae-Hyun Lim, Ju-Hyoung Kim, Hyo-Ryeon Kim, Seo-Young Kim, Il-Nam Kim

“…During August 2021, most sites functioned as sources of N₂O, CH₄, and CO₂ to the atmosphere. …”
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Artificial Intelligence Methods Applied to Catalytic Cracking Processes by Fan Yang, Mao Xu, Wenqiang Lei, Jiancheng Lv

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ARACOV-02. Specialized nutritional intervention and telerehabilitation in patients with long COVID: Protocol of a randomized controlled trial. by Beatriz Carpallo-Porcar, Carolina Jiménez-Sánchez, Sandra Calvo, Pilar Irún, Elena Kolesnyk-Sumskaya, Ana Isabel Aller-Blanco, Esther Del Corral Beamonte

“…The objective is to determine the change in quality of life, inflammatory profile, functional capacity and emotional variables in a group taking a nutritional supplement (SPMs) plus a telerehabilitation programme.…”
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Approach of Model Extension for Virtual Commissioning to Predict Energy Consumption of Production Systems by Leon Hollas, Christer-Clifford Schenke, Arvid Hellmich

“…This model is then exported as a Functional Mock-Up Unit (FMU) and co-simulated within a virtual commissioning environment. …”
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Capacity planning of hydro-wind-solar hybrid power systems considering hydropower forbidden zones by Zhiyu Yan, Lu Zhang, Fulong Song

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Reevaluating multi-pool first-order kinetic models for fitting soil incubation data by Shuhao Zhou, Daifeng Xiang, Gangsheng Wang, Liping Zhang, Zehao Lv, Shanshan Qi, Wanyu Li

“…The results are regardless of the objective function used for model fitting (i.e., maximizing R2 for instantaneous or cumulative C effluxes). …”
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Insight into the Microbiota of Orthopteran in Relation to Gut Compartmentalisation by Thierry Hance, Alisa Hamidovic, Siripuk Suraporn

“…This review first provides an overview of the functional diversity of Orthoptera-associated microbiota and the services they provide to their hosts. …”
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WRF-ELM v1.0: a regional climate model to study land–atmosphere interactions over heterogeneous land use regions by H. Huang, Y. Qian, G. Bisht, J. Wang, T. Chakraborty, D. Hao, J. Li, T. Thurber, B. Singh, Z. Yang, Y. Liu, P. Xue, P. Xue, W. J. Sacks, E. Coon, R. Hetland

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