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1021
Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro
Published 2025-08-01“…Methods The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
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1022
Hemodynamic homeostasis disequilibrium in critical illness
Published 2025-07-01“…Over millions of years, the circulatory system evolved from primitive forms into a highly specialized network capable of overcoming time-distance constraints and enhancing diffusion efficiency. This structural advancement laid the physiological foundation for the regulation of hemodynamics and systemic homeostasis. …”
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1023
Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry
Published 2025-05-01“…An elastic net was used to identify significant variables to enter a best subsets logistic regression. …”
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1024
Framework for extracting multi-objective operation rules for cascade reservoirs based on causal features and physical mechanisms
Published 2025-08-01“…To reduce high dimensionality, Convergent Cross Mapping (CCM) quantifies causal relationships between features and decision variables. Moreover, embedding physical constraints into the model’s loss function further enhances interpretability. …”
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1025
The Effect of Hydraulic Partitioning on Prediction the Rate of Bed Load Transport in Gravel-bed Rivers using Support Vector Machine
Published 2019-03-01“…Evaluation and prediction of sediment transport and associated processes have been one of the main issues of hydraulic and river engineers. There are some variables which affect the amount of bed load of a stream or river which may carry such as hydraulic, hydrological and sediment parameters caused the complexity of sediment transport phenomenon. …”
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1026
Reliability optimization methods: A systematic literature review
Published 2025-01-01“…Additionally, which variables influence the primary reliability metrics in their work and how? …”
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1027
Understanding the Role of Organic Hole Transport Layers on Pinhole Blocking and Performance Improvement in Sb2Se3 Solar Cells
Published 2024-12-01“…After successive record‐efficiencies using a range of device structures, spiro‐OMeTAD has emerged as the default hole transport material (HTM), however, the function of HTM layers remains poorly understood. …”
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1028
Factors Influencing Telemedicine Adoption Among Health Care Professionals: Qualitative Interview Study
Published 2025-01-01“…Perceived benefits encompassed convenience through reduced travel time (5/14, 36%), improved care quality due to higher accessibility (8/14, 57%), and operational efficiency (7/14, 50%). Trust referents played a pivotal role; trust in technology was linked to functionality (6/14, 43%) and reliability (5/14, 36%), while trust in treatment depended on effective collaboration (9/14, 64%). …”
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1029
Mechatronic system for running-in and testing of mechanical transmissions in mining shovels
Published 2025-03-01“…The mechanical transmissions of the hoist and drag winches, as well as the crowd mechanisms of mining shovels, operate under highly variable and shock cyclic loads. These severe operating conditions impose stringent quality requirements on both the manufacturing and assembly of such transmissions. …”
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1030
Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents
Published 2024-07-01“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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1031
Gut health modulation through phytogenics in poultry: mechanisms, benefits, and applications
Published 2025-08-01“…PFAs are valuable tools for sustainable poultry production since they have been connected to enhanced feed conversion efficiency, growth performance, and meat quality in addition to their health benefits. …”
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1032
Dynamic Gesture Recognition Algorithm Combining Global Gesture Motion and Local Finger Motion for Interactive Teaching
Published 2024-01-01“…Adding dynamic gesture recognition to the new interactive teaching system is of great significance to improve the teaching efficiency. However, the features extracted by traditional dynamic gesture recognition methods are usually difficult to accurately represent the differences between dynamic gestures. …”
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1033
The influence of fitness mobile apps on workout behavior intention among Chinese young adults.
Published 2025-01-01“…Three components of belief were examined: self-efficiency, perceived barriers, and perceived benefits. …”
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1034
A robust deep learning approach for photovoltaic power forecasting based on feature selection and variational mode decomposition
Published 2025-08-01“…Three feature selection methods---ReliefF, Minimum Correlation, and Minimum Redundancy Maximum Relevance (MRMR)---are employed to identify the most relevant input variables from a dataset collected in the Ghardaia region. …”
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1035
Development and evaluation of a predictive model of upper gastrointestinal bleeding in liver cirrhosis
Published 2025-03-01“…Once bleeding occurs, the risk of recurrent episodes substantially increases, further compromising liver function and worsening patient outcomes. This study aims to identify risk factors for UGIB in cirrhotic patients using clinical examination data and to develop a non-invasive predictive model to improve diagnostic precision and efficiency. …”
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1036
Potential Protective Effect of Orlistat: A Formulation of Nanocrystals Targeting Inflammation, Oxidative Stress, and Apoptosis in an Experimental Model of Doxorubicin-Induced Cardi...
Published 2024-10-01“…Furthermore, Orli has a favorable impact on the decrease in cardiometabolic risk variables. Thus, this study aimed to investigate the novel use of Orlistat Nanocrystals (Orli-Nanocrystals) to mitigate DOX-induced cardiotoxicity and to identify probable pathways behind the cardioprotective effects. …”
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1037
Mi-DETR: For Mitosis Detection From Breast Histopathology Images an Improved DETR
Published 2024-01-01“…In the decoder layer, unnecessary model parameters have been filtered out using a layer reduction strategy to improve model efficiency and reduce computational costs. Additionally, a more stable model has been obtained by using the CIoU loss function instead of the L1+GIoU loss function used in the DETR model. …”
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1038
Comparative Study on the Treatment Effect of Stretching and High-frequency Diathermy in Subjects With Gastrocnemius Tightness
Published 2025-04-01“…Background: Ankle flexibility is important for maintaining proper biomechanical function. Static stretching is used to improve flexibility with minimal risk; however, its effects are often temporary. …”
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1039
Cultivares de trigo submetidas a déficit hídrico no início do florescimento, em casa de vegetação Wheat cultivars submitted to water deficit at the beginning of flowering in greenh...
Published 2012-08-01“…Reduction was found in the gravimetric soil moisture, in the relative levels of water and in all biometric variables, in function of the water deficit. The grain production showed difference only among the water regimes, in which the cultivar CD 111 is more efficient in the maintenance of the productive potential in conditions of water deficit, through the quick recovery in the relative content of water in leaves.…”
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1040
Multi-objective optimization of an open-pit mining system to determine safety buffer using the modified NBI method and the meta-model approach
Published 2025-03-01“…The central composite design (CCD) method was used to develop the design of experiments (DOE) for the design variables. Results: according to obtained findings, the considered design variables were the number of trucks of 120 tons, 240 tons, 35 tons, and 100 tons. …”
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