A reduced simulation applied to viscoelastic fatigue of polymers using a time multi-scale approach based on partition of Unity method by Sebastian Rodriguez, Angelo Pasquale, Jad Mounayer, Diego Canales, Marianne Beringhier, Chady Ghnatios, Amine Ammar, Francisco Chinesta

“…In this context, the use of a space-time PGD approximation is proposed here to boost their resolution, where the temporal functions are constructed following a multi-scale strategy along with the partition of unity method, in order to catch each dynamic efficiently. …”
Get full text

On a Solution of a Third Kind Mixed Integro-Differential Equation with Singular Kernel Using Orthogonal Polynomial Method by Ahmad Alalyani, M. A. Abdou, M. Basseem

“…While when using the separation method, we are able to obtain FIE with time coefficients, and these functions are described as an integral operator in time. …”
Get full text

Ultrasonographic Nomograms of Foetal Fourth Ventricle Biometry and its Correlation with Transcerebellar Diameter and Gestational Age among Normal Foetuses: A Cross-sectional Study by N Padmalatha, Paarthipan, Parthasarathy, Francis Nanda Prakash Monteiro

“…Regression analysis was performed to determine the equation of the linear fitted function with each of the independent variables (GA, TCD). …”
Get full text

THE BONITATION METHOD FOR ASSESSING THE FERTILITY OF THE CHERNOZEM by Mariana BURCEA, Nicoleta OLTENACU

“…Statistical indicators have been determined using the functions from Excel Program, such as: average, standard deviation, coefficient of variability, annual growth rate. …”
Get full text

Correlation between Stressful Life Events and Suicidal Ideation among Patients with Schizophrenia in Remission Stage: A Cross-sectional Study by Ashok Silamban, Kailash Sureshkumar, Aravindh Manogaran, Shabeeba Z Kailash

“…Introduction: Patients with schizophrenia often exhibit impaired executive brain function, which disrupts their daily activities. Relapse in schizophrenia has been linked to stressful life events. …”
Get full text

Research on Geometric Mappings in Complex Systems Analysis by Yanyan Cui, Chaojun Wang, Sifeng Zhu

“…We mainly discuss the properties of a new subclass of starlike functions, namely, almost starlike functions of complex order λ, in one and several complex variables. …”
Get full text

Predictor Importance for Hydrological Fluxes of Global Hydrological and Land Surface Models by João Paulo L. F. Brêda, Lieke A. Melsen, Ioannis Athanasiadis, Albert VanDijk, Vinícius A. Siqueira, Anne Verhoef, Yijian Zeng, Martine van derPloeg

“…We analyzed the JULES, ORCHIDEE, HTESSEL, SURFEX, and PCR‐GLOBWB models for the relative importance of precipitation, climate, soil, land cover and topographic slope as predictors of simulated average evaporation, runoff, and surface and subsurface runoff. RF models functioned as a metamodel and could reproduce GHM/LSMs outputs with a coefficient of determination (R2) over 0.85 in all cases and often considerably better. …”
Get full text

Non-Iterative Estimation of Multiscale Geographically and Temporally Weighted Regression Model by Ya-Di Dai, Hui-Guo Zhang

“…The results demonstrate that the non-iterative estimation method for MGTWR significantly enhances computational efficiency while effectively capturing the scale effects of spatiotemporal variation in the regression coefficient functions for each predictor.…”
Get full text

A MODEL OF AGE–STRUCTURED POPULATION UNDER STOCHASTIC PERTURBATION OF DEATH AND BIRTH RATES by Maxim A. Alshanskiy

“…Under consideration is construction of a model of age-structured population reflecting random oscillations of the death and birth rate functions. We arrive at an Itô-type difference equation in a Hilbert space of functions which can not be transformed into a proper Itô equation via passing to the limit procedure due to the properties of the operator coefficients. …”
Get full text

Multiobjective Optimization of Stress-Release Boot of Solid Rocket Motor under Vertical Storage Based on RBF Model by Qiuwen Miao, Huihui Zhang, Zhibin Shen, Weiyong Zhou

“…Stress-release boot can effectively improve the structural integrity of SRM (solid rocket motor), but it will also influence the loading fraction and interior ballistic performance, so the purpose of this paper is to propose a multiobjective optimization method for stress-release boot. The design variables are the front and rear depth of the stress-release boot, and four optimization variables were determined according to the analysis of SRM performance. …”
Get full text

Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer by Lei Shi, Lei Shi, Lei Shi, Xuyang Zhong, Jiafeng Liu, Yong Ying, Zibing Liao, Jin Liu, Liwen Zhao, Jianing Zhong, Jianing Zhong, Xiangtai Zeng, Xiangtai Zeng

“…We systematically dissect the multifaceted regulatory circuits governing lactate metabolism by integrating three pivotal dimensions: (i) canonical signaling cascades; (ii) tumor-microenvironmental variables, most notably hypoxia and acidosis; and (iii) the emerging epigenetic paradigm of lactylation, which dynamically reprograms the catalytic efficiency of rate-limiting enzymes and reshapes the transcriptional landscape of metabolic genes, thereby precisely coordinating lactate homeostasis. …”
Get full text

Impact of pulmonary rehabilitation in sleep in COPD patients measured by actigraphy. by Suman B Thapamagar, Kathleen Ellstrom, James D Anholm, Ramiz A Fargo, Nagamani Dandamudi

“…Paired comparisons (t-test or Wilcoxon-signed-rank test) were performed before and after PR data on all variables.<h4>Methods</h4>This retrospective study of COPD patients undergoing PR utilized actigraphy watch recordings before and after 8-weeks of PR to assess changes in sleep variables including total time in bed (TBT), total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), wakefulness after sleep onset (WASO) and total nocturnal awakenings. …”
Get full text

Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
Get full text

Application of multi-objective neural network algorithm in industrial polymerization reactors for reducing energy cost and maximising productivity by Fakhrony Sholahudin Rohman, Sharifah Rafidah Wan Alwi, Dinie Muhammad, Ashraf Azmi, Zainuddin Abd Manan, Jeng Shiun Lim, Hong An Er, Siti Nor Azreen Ahmad Termizi

“…According to their preferences, decision-makers can use the resulting Pareto to decide on the most acceptable alternative. The decision variable plots show that both initiators in the reacting zone highly affected the optimal solution with the opposite action.…”
Get full text

The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass by Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément

Get full text

REVIVAL OF TOURISM DEMAND IN THE POST COVID-19 PANDEMIC PERIOD - A STATISTICAL OVERVIEW IN ROMANIA by Agatha POPESCU, Cristina TINDECHE, Alina MARCUTA, Liviu MARCUTA, Adelaida HONTUS, Mirela STANCIU, Daniela-Mirela PLESOIANU

“…Dynamics of the tourist arrivals and overnight stays involved to establish the trend using polynomial regression functions and determination coefficient. The results showed that the recovery of the tourist flow from its lowest level registered in 2020, the worst year of tourism during the pandemic, needed three years to attain a higher performance than in 2019, a year which was considered the peak in Romania's tourism. …”
Get full text

Vibration Analysis of Rotating Tapered Timoshenko Beams by a New Finite Element Model by Bulent Yardimoglu

“…A new finite element model is developed and subsequently used for transverse vibrations of tapered Timoshenko beams with rectangular cross-section. The displacement functions of the finite element are derived from the coupled displacement field (the polynomial coefficients of transverse displacement and cross-sectional rotation are coupled through consideration of the differential equations of equilibrium) approach by considering the tapering functions of breadth and depth of the beam. …”
Get full text

Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Methods‍　‍The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
Get full text

Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Interestingly, some of the production- and health-related variables investigated showed significant improvement even when compared with control chickens. …”
Get full text

A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…The cohort was randomly divided into a 70% training set and a 30% validation set. Relevant variables were selected through univariate and multivariate analyses in the training set. …”
Get full text