Impact of pulmonary rehabilitation in sleep in COPD patients measured by actigraphy. by Suman B Thapamagar, Kathleen Ellstrom, James D Anholm, Ramiz A Fargo, Nagamani Dandamudi

“…Paired comparisons (t-test or Wilcoxon-signed-rank test) were performed before and after PR data on all variables.<h4>Methods</h4>This retrospective study of COPD patients undergoing PR utilized actigraphy watch recordings before and after 8-weeks of PR to assess changes in sleep variables including total time in bed (TBT), total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), wakefulness after sleep onset (WASO) and total nocturnal awakenings. …”
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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Application of multi-objective neural network algorithm in industrial polymerization reactors for reducing energy cost and maximising productivity by Fakhrony Sholahudin Rohman, Sharifah Rafidah Wan Alwi, Dinie Muhammad, Ashraf Azmi, Zainuddin Abd Manan, Jeng Shiun Lim, Hong An Er, Siti Nor Azreen Ahmad Termizi

“…According to their preferences, decision-makers can use the resulting Pareto to decide on the most acceptable alternative. The decision variable plots show that both initiators in the reacting zone highly affected the optimal solution with the opposite action.…”
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The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass by Jean Debédat, Tiphaine Le Roy, Lise Voland, Eugeni Belda, Rohia Alili, Solia Adriouch, Pierre Bel Lassen, Kazuyuki Kasahara, Evan Hutchison, Laurent Genser, Licia Torres, Camille Gamblin, Christine Rouault, Jean-Daniel Zucker, Nathalie Kapel, Christine Poitou, Geneviève Marcelin, Federico E. Rey, Judith Aron-Wisnewsky, Karine Clément

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Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Methods‍　‍The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
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Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Interestingly, some of the production- and health-related variables investigated showed significant improvement even when compared with control chickens. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…The cohort was randomly divided into a 70% training set and a 30% validation set. Relevant variables were selected through univariate and multivariate analyses in the training set. …”
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New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery by Justin E. Kung, Chase Gauthier, Yianni Bakaes, Michael Spitnale, Richard A. Bidwell, David G. Edelman, Heidi C. Ventresca, J. Benjamin Jackson, Shari Cui, Gregory Grabowski

“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…Pregnancy rate at first service, however, was analyzed using logistic regression and the same explanatory variables. The metabolites linked to liver function and damage, such as aspartate aminotransferase, total bilirubin, and alkaline phosphatase, had a relevant influence on iCF and DO in terms of the hazard ratio (HR). …”
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Optimization Study of PVT Coupled Water Loop Heat Pump Energy Supply System by Lv Tiangang, Liu Bing, Wu Jun, Zhu Li, Hou Jingxuan

“…By employing the Hooke-Jeeves algorithm, the system's design and operation parameters were optimized with annual cost and system COP as objective functions. Design variables included PVT inclination, azimuth, area, heat pump capacity, and tank volume, while operational variables were PVT backplate temperature and tank temperature. …”
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Optimization of K-Shaped Metal Sealing Ring for Subsea Tubing Hanger Based on Response Surface Method by Huan Xie, Hongxia Zhang, Yiwei Fan, Liyuan Liu, Wei Zeng

“…To address the issue of low optimization efficiency due to the need for repeated finite element calculations during the optimization process, quadratic response surface models are established for the sealing performance indicators of the K-shaped seal ring, which were then used as the optimization objective functions to enhance the optimization efficiency. …”
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Protein expression profiling identifies a prognostic model for ovarian cancer by Luyang Xiong, Jiahong Tan, Yuchen Feng, Daoqi Wang, Xudong Liu, Yun Feng, Shusheng Li

“…Patients with complete information concerning protein expression, survival, and clinical variables were included. A risk model was then constructed by performing multiple Cox regression analysis. …”
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‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’ by Natale Massimino Ucin, Manassé Nimpagaritse, Shital Mahindra Maru, Mulatedzi Makhado, Shiferaw Mitiku Tebeka

“…Abstract Background of the study Along with developments in the clinical domain, medical equipment is becoming more sophisticated, and it needs to function at peak efficiency. In this case, hospitals should priorities the prompt and effective maintenance of life-saving equipment. …”
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Effect of Central Motor and Neuromuscular Impairments on Front Crawl Body Roll Characteristics of Para Swimmers by Yu-Hsien Lee, Dawn Nicola O’Dowd, Luke Hogarth, Brendan Burkett, Carl Payton

“…CMNI swimmers were divided into three upper-limb [mild (n = 9), moderate (n = 9), severe (n = 9)] and three lower-limb function subgroups [bilateral (n = 2), unilateral (n = 6), without kick (n = 19)] based on their Froude efficiency (a measure of how effectively upper limbs contribute to propulsion) and the number of lower limbs actively kicking during trials, respectively. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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Optimal control for high-precision repeat ground-track orbits via convex optimization by Yanchao HE, Lei ZHANG, Yijun YANG, Qian CHEN

“…These maneuvers are minimized by formulating a SOCP problem via a lossless convexification with the introduction of slack variables (i.e., impulse magnitude) while enforcing position and velocity state constraints at the Poincaré crossings. …”
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SCIENCE TEACHERS’ ICT USE FREQUENCY AND THE BARRIERS THEY WERE EXPOSED by Fatma TAŞKIN EKİCİ, Seçil DEMİRHAN, İzzet KARA, Erhan EKİCİ

“…There are no statistical differences by these variables. Solely, the teachers already taken courses related to ICT and their use are stated that more frequent use than teachers didn’t take significant in statistical mean.…”
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Sinc-Chebyshev Collocation Method for a Class of Fractional Diffusion-Wave Equations by Zhi Mao, Aiguo Xiao, Zuguo Yu, Long Shi

“…This paper is devoted to investigating the numerical solution for a class of fractional diffusion-wave equations with a variable coefficient where the fractional derivatives are described in the Caputo sense. …”
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Optimal selection of satellite XCO₂ images for urban CO₂ emission monitoring by A. Danjou, G. Broquet, A. Schuh, F.-M. Bréon, T. Lauvaux, T. Lauvaux

“…This study analyzes the performances of an automated method for estimating urban emissions as a function of the targeted cities and of the atmospheric conditions. …”
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أثر كفاءة الجھاز التنفسي في ألانجاز الرقمي لعدائي ( -5001500 للشباب بأعمار دون( 20 )سنة by عباس فاضل جابر, ماهر عبداللطيف عارف

“… A study conducted on a sample of runners ran (1500 m -5000 m) youth Reconstruction without (20) years to know the effect of the efficiency of the respiratory tract in the achievement digital The study aimed to identify the impact of the efficiency of the respiratory system of delivery for digital hostile (1500-5000) meters for youth ages without 20 years old and to identify the relationship between some of the functions of breath and time ran 1,500 meters and 5,000 meters for young people under the age of 20 years and get the equation predictive time-ran 1,500 meters and 5,000 meters for young people under the age of 20 years have been identified measurements that will be used in the research is vital capacity of the lungs VC)) and vital capacity rapid ( FVC) and the volume of exhaled air after the first second (FEV1) and the percentage of the volume of exhaled air after the first second (FEV1%) and the average maximum speed of exhalation (MMF) and compression force exhaled air - rate the passage of exhaled air (PEF) has concluded the researchers to some of the findings, including the existence of correlation between some of the functions of breath and time ran (1500-5000) meters for youth and appeared vital capacity of the lungs during rest (VCr) preference efficiency Respiratory to hostile five thousand meters on the hostile thousand and five hundred meters clearly. emerged as functions of breathing contribute to the time he ran (1500) m is the rate of passage of exhaled air PEF and jointly by (41.55%), followed by vital capacity maximum (FVC) by (5.71%) and the volume exhaled air after the first second (FEV1) increased by 3.55% and the three variables contribute by 49.11% at the time ran the 1,500 meters. …”
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