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qBiCo: a method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements
Published 2025-01-01“…Depending on the starting DNA quantity, bisulfite-converted DNA recoveries ranged from 8.5 to 100%, conversion efficiencies from 78 to 99.9%, while certain kits highly fragment DNA, demonstrating large variability in their performance. …”
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502
Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.
Published 2013-01-01“…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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503
Statistical learning-driven parameter tuning in injection molding using modified simplex method
Published 2025-09-01“…The Taguchi design of experiments and desirability function analysis were employed to establish a baseline. …”
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504
Eficiência técnica na suinocultura: efeitos dos gastos com meio ambiente e da renúncia fiscal Technical efficiency in swine breeding: effect of the expenses with the environment an...
Published 2008-04-01“…After estimating the technical efficiency indices with data of ten properties situated in Mato Grosso from production functions, whose dependent variable is represented by the production of swine and the independent ones are the consumption of water, electricity and the amount of workers directly tied with the productive process. …”
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505
Methodology for assessing the spherical plain bearings durability
Published 2025-05-01Get full text
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506
Three-dimensional design, simulation and optimization of a centrifugal compressor impeller with double-splitter blades
Published 2025-02-01“…Since the optimization process only using genetic algorithms is very time-consuming and has high computational costs, artificial neural networks were used to reduce costs. The objective function in this optimization process was to increase efficiency while maintaining the flow rate and pressure ratio at the design point. …”
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507
Multifractal analysis of Bitcoin price dynamics
Published 2025-02-01“… This research employs Multifractal Detrended Fluctuation Analysis (MFDFA) to investigate multifractal properties in financial variables, including Bitcoin prices and economic indicators. …”
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508
Study on Operation Control Strategy for Campus Public Building Heating Systems in Severe Cold Areas
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509
Direct methanol fuel cells parameter identification with enhanced algorithmic technique
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510
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511
Experimental investigation of solar PVT collector with the dryer on mass and temperature of dried red chili with Machine Learning Models
Published 2025-09-01“…Machine learning (ML) models, namely the Multilayer Perceptron (MLP), Radial Basis Function (RBF), and Decision Tree (DT), were used to forecast the temperature and mass dryness variables.The RBF model showed the best performance with 0.98, 0.95, and 0.92 for temperature dryness, above MLP and DM. …”
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512
Internal Benchmarking of Thermal Power Plants оf Electric Power Systems
Published 2020-12-01“…A necessary condition for the feasibility of using these or those integral indicators is their functional and statistical independence. The results of the studies performed using the simulation method made it possible to establish that the smallest correlation occurs between the integral indicator calculated as the arithmetic mean of random variables and the integral indicator calculated as the coefficient of variation of the same random variables. …”
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513
STRUCTURAL RELIABILITY OPTIMIZATION DESIGN OF REINFORCED SHELL MODEL BASED ON ADAPTIVE SURROGATE MODEL
Published 2024-01-01“…Reinforced shell structure is widely used in aerospace load-bearing structures because its high specific stiffness and specific strength.By considering the uncertainty and risk factors in the structural parameters,the Reliability-Based Design Optimization (RBDO) can avoid the overly conservative design of the structure and ensure its reliability and safety.An efficient RBDO method based on adaptive agent model was proposed.This method solves the problem of lightweight design of reinforced shell structure under buckling reliability constraints.The adaptive addition of sample points was implemented through the expected feasibility function criterion,and the discrete variables was continued by constructing piecewise functions.This increases optimization efficiency while ensuring the reliability of design results.Finally,the effectiveness of the proposed method is verified by comparing the RBDO results with the deterministic optimization results.…”
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514
Vehicle detection method based on multi-layer selective feature for UAV aerial images
Published 2025-07-01“…However, this task remains challenging due to variable high-altitude viewpoints, complex environmental interference, and limitations in algorithmic efficiency. …”
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515
Natural assets, changes, and variations of the socioeconomic-environmental systems along the Asian drylands belt
Published 2024-01-01“…We found increased variability as well as spikes in extreme values in each of these three measures of SES function among the 23 PEs over the study period. …”
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THE COMPUTER-AIDED CONTROLLING OF TECHNICAL AND TECHNOLOGICAL PLANTS IN THE WAVELET MEDIUM
Published 2015-03-01“…Methods of formalizing material flows created in certain knots of structure-and-functional diagram of the mixture producing aggregate are considered, that are founded on transforming one-dimensional initial flow signals into multi-dimensional ones. …”
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518
Multiobjective optimization of Murta (Ugni molinae Turcz) juice lactic acid fermentation with monocultures and cocultures of Lactobacillus acidophilus and Lactiplantibacillus plant...
Published 2025-06-01“…These findings highlight the practical utility of MOO-MCDM for designing efficient multiobjective fermentation processes in functional food development.…”
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519
Artificial intelligence-driven fuzzy logic approach for optimal well selection in gas lift design: A brown field case study
Published 2025-03-01“…However, selecting suitable wells for gas lift is complex due to the inherent uncertainty and variability in petroleum production data. Traditional decision-making approaches often struggle with this uncertainty, leading to suboptimal choices that can reduce efficiency and increase operational costs. …”
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520
Community re-entry program on global functioning and medication adherence among bipolar affective disorder patients- A randomized controlled trial pilot study
Published 2025-07-01“…This quantitative study to explores the effectiveness of community re-entry program on global functioning and medication adherence for patients with bipolar affective disorder. …”
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