Impact of IgG subclass on monoclonal antibody developability by Paul Cain, Lihua Huang, Yu Tang, Victor Anguiano, Yiqing Feng

“…We thus conducted a systematic study of 12 mAbs derived from three sets of unrelated variable regions, each cloned into IgG1, an IgG1 variant with diminished effector functions, IgG2, and a stabilized IgG4 variant with further reduced FcγR interaction, to evaluate the impact of IgG subclass on manufacturability and high concentration stability in a common formulation buffer matrix. …”
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Optimum System Design Using Rough Interval Multi-Objective De Novo Programming by Iftikhar Hussein, Hegazy Zaher, Naglaa Ragaa Saeid, Hebaa Sayed Roshdy

“…This paper suggested a new approach for solving uncertainty of De novo programming problems (DNP) using a combination model consisting of a rough interval multi-objective programming (RIMOP) and DNP, where coefficients of decision variables of objective functions and constraints are rough intervals (RIC). …”
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Versatile machine learning algorithms for FTIR spectroscopy: differentiating crosslinked and non-crosslinked gelatin samples by Juliana Rincón-López, Eliana Álvarez-Valdés, Daniela Velez-Arango, Estefanía Rojas Zuleta, Leidy Yuliana Vargas Soto, Liliana Lellesch, Victor Alonso García Londoño, Milton Rosero-Moreano, Gonzalo Taborda-Ocampo

“…This is a mixture of amino acid polymers with a variable molecular weight and a diversity of secondary structures (α, β and γ chains). …”
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COSP-RTTOV-1.0: flexible radiation diagnostics to enable new science applications in model evaluation, climate change detection, and satellite mission design by J. K. Shaw, J. K. Shaw, D. J. Swales, S. DeSouza-Machado, D. D. Turner, J. E. Kay, J. E. Kay, D. P. Schneider

“…Outputs from COSP-RTTOV are consistent with instrument spectral response functions, orbit sampling, and the physics of the host model. …”
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AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing by Prakaimuk Saraithong, Peyton Krajcarski, Yukako Kusaka, Moe Yamada, Junichi Matsumoto, Hailey Cunningham, Sama Salih, Darby Jones, Devika Baddhan, Christian Hausner, Justus Anumonwo, Anthony Rosenzweig, Mary M. Navarro, Luis Villa Diaz, Joseph Criscione, Deok-Ho Kim, Todd J. Herron

“…This streamlined process preserves cardiomyocyte viability and function, offering a scalable and efficient solution for cardiac regenerative medicine, disease modeling, and drug discovery.…”
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Classification of traffic accidents’ factors using TrafficRiskClassifier by Wei Sun, Lili Nurliyana Abdullah, Fatimah binti Khalid, Puteri Suhaiza binti Sulaiman

“…Furthermore, the TrafficRiskClassifier model delineates a functional nexus between accident risk and variables such as weather, road conditions, and personal factors, employing a polynomial regression approach. …”
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Large live biomass carbon losses from droughts in the northern temperate ecosystems during 2016-2022 by Xiaojun Li, Philippe Ciais, Rasmus Fensholt, Jérome Chave, Stephen Sitch, Josep G. Canadell, Martin Brandt, Lei Fan, Xiangming Xiao, Shengli Tao, Huan Wang, Clément Albergel, Hui Yang, Frédéric Frappart, Mengjia Wang, Ana Bastos, Philippe Maisongrande, Yuanwei Qin, Zanpin Xing, Tianxiang Cui, Ling Yu, Lei He, Yi Zheng, Xiangzhuo Liu, Yuqing Liu, Aurelien De Truchis, Jean-Pierre Wigneron

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A New Modeling Method for Meteorological Information of Regional Distributed Photovoltaic Power Generation Based on Multi‐Source Information Fusion by Yuhang Wang, Dengxuan Li, Wenwen Ma, Xi Zhang, Honglu Zhu

“…Consequently, developing effective, reliable, and cost‐efficient meteorological information computation methods for DPV has become a critical research focus. …”
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Optimizing urban energy flows: Integrative vehicle-to-building strategies and renewable energy management by Jian Hern Yeoh, Kai-Yun Lo, I-Yun Lisa Hsieh

“…The optimization tasks are handled using the Sequential Least Squares Programming (SLSQP) algorithm, which is well-suited for managing quadratic objective functions, nonlinear constraints, and bounded variables. …”
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Internal Control Systems and Quality Service Delivery: A Case Study of Kabale Municipal Council. by Ahimbisibwe, Laban Isaac

“…Recommendations encouraged that procurement personnel and accounting officers be given training on the need and value of having functional internal control systems as well as enabling other organizational members to adopt the currently available internal controls for effective and efficient service delivery while areas for further improvement suggested that research be carried out to in other public entities to determine how internal control affects service delivery.…”
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Field Testing of a Smart Geomat Based on Fiber Optic Sensors and Sensor Fusion for Levee Monitoring by Manuel Bertulessi, Francesca Ceccato, Francesco Ioli, Federico Barbieri, Livio Pinto, Paolo Simonini, Giovanni Menduni

“…ABSTRACT Real‐time monitoring of the functionality of river embankments, especially during flood events, is an increasingly important topic in the new scenario outlined by climate change. …”
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Elucidating Genotypic Variation in Quinoa via Multidimensional Agronomic, Physiological, and Biochemical Assessments by Samreen Nazeer, Muhammad Zubair Akram

“…The results revealed that significant variation was observed across all measured parameters, highlighting the diverse adaptive strategies and functional capacities among the tested genotypes. More specifically, genotypes Q4, Q11, Q15, and Q126 demonstrated superior agronomic potential and canopy-level physiological efficiencies, including high biomass accumulation, low infrared canopy temperatures and sustained NDVI values. …”
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Organizational and Economic Factors of Health System Optimization by Oleksandr Telizhenko, Yuliia Halynska, Nataliia Baistriuchenko, Volodymyr Potseluiev, Kateryna Demchuk

“…To this aim, the factors that influence the efficiency of the organization and functioning of the medical system are identified. …”
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PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival by Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik

“…This is typically done by ex vivo stimulation with cytokines to enhance functionality or expansion for 10-14 days to increase both their activity and quantity. …”
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The operational municipal solid waste management policy focuses on identifying waste generation behavior across multiple levels in mega cities, a case study by Hamed Alimoradiyan, Ahmad Hajinezhad, Hossein Yousefi, Mario Giampietro

“…Abstract The results of an effort to create a thorough framework that efficiently arranges and combines quantitative data characterizing the performance of Urban Waste Management Systems (UWMS) across a range of scales and dimensions are presented in this study. …”
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Wafer‐Scale Synthesis of Topological Insulator Sb2Te3 Thin Films by Ali Shafiei, Ahmad Fathi Hafshejani, Rehab M. G. Ahmed, Alessio Lamperti, Emanuele Longo, Lorenzo Locatelli, Christian Martella, Alessandro Molle, Graziella Tallarida, Carlo Zucchetti, Claudia Wiemer, Massimo Longo, Roberto Mantovan

“…Furthermore, comprehensive information on the variability of the functional properties of Sb2Te3 thin films with their morphological, chemical, and structural properties, as probed by scanning electron microscopy, X‐ray diffraction/reflectivity, atomic force microscopy, Raman spectroscopy, time‐of‐flight secondary ion mass spectrometry, and energy‐dispersive X‐ray analyses is reported. …”
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Deletion of genes linked to the C1-fixing gene cluster affects growth, by-products, and proteome of Clostridium autoethanogenum by Ugochi Jennifer Nwaokorie, Kristina Reinmets, Lorena Azevedo de Lima, Pratik Rajendra Pawar, Kurshedaktar Majibullah Shaikh, Audrey Harris, Michael Köpke, Kaspar Valgepea

“…However, our understanding of the functionalities of the genes involved in the C1-fixing gene cluster and its closely-linked genes is incomplete. …”
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Enhancer chip: detecting human copy number variations in regulatory elements. by Marco Savarese, Giulio Piluso, Daniela Orteschi, Giuseppina Di Fruscio, Manuela Dionisi, Francesca del Vecchio Blanco, Annalaura Torella, Teresa Giugliano, Michele Iacomino, Marcella Zollino, Giovanni Neri, Vincenzo Nigro

“…Validation experiments have demonstrated that Enhancer Chip efficiently detects duplications and deletions covering enhancer loci, demonstrating that it is a powerful instrument to detect and characterize copy number variable enhancers.…”
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Cognitive ability and motor performances in the elderly by Jovanović Stevan S., Stojanović-Jovanović Biljana N., Pavlović Aleksandra M., Milošević Radovan Lj., Pavlović Dragan M.

“…Several MoCA items demonstrated relatively low variability, i.e., they proved to be too easy for most of the participants. …”
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Structural network topologies are associated with deep brain stimulation outcomes in Meige syndrome by Bin Liu, Zhiqi Mao, Xinyuan Yan, Hang Yang, Junpeng Xu, Zhebin Feng, Yanyang Zhang, Xinguang Yu

“…However, the DBS efficacy varies across MS patients and the factors contributing to the variable responses remain enigmatic. We aim to explain the difference in DBS efficacy from a network perspective. …”
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