Study of the influence of population immunity to tick-borne encephalitis virus on the characteristics of the epidemic process in Russia by Temur K. Muminov, Vladimir A. Gushchin, Vladimir A. Gushchin, Vladimir A. Gushchin, Denis A. Kleymenov, Artem P. Tkachuk, Artem P. Tkachuk, Viktor A. Manuylov, Viktor A. Manuylov, Andrei E. Siniavin, Andrei E. Siniavin, Daria A. Ogarkova, Nadezhda A. Kuznetsova, Vladimir I. Zlobin, Alexander L. Gintsburg, Alexander L. Gintsburg

“…All volunteers completed questionnaires to collect demographic data, information about residence, TBE vaccination, and tick bites.ResultsOur study included participants from non-endemic (Moscow and the Republic of Dagestan) and endemic regions (Moscow Region, St. …”
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Fertility intentions among Chinese adults: a cross-sectional study using a national survey by Mingyan Hao, Chenxiao Zhang, Haofeng Fu, Jingting Zhang, Ziyi Zhang, Baotong Ma, Ruitong Xia, Yuanwei Lu, Jingwen Liu, Hanjia Xin, Yumeng Cao, Saier Yang, Runqing Li, Ji Zhao, Jin Zhang, Zheng Gao, Yaxin Zeng, Yixiao Ding, Zhuolun Ren, Yan Guan, Na Zhang, Jia Li, Yan Ma, Pei Wei, Jingjing Dong, Chen Chen, Yajing Zhou, Jianzhong Zheng, Wei Liu, Lizheng Wang

“…Methods In our research, we performed a cross-sectional analysis using data gathered in 2022 from the Psychology and Behavior Investigation of Chinese Residents (PBICR), which encompassed 21,916 participants aged 18 to 49 years. …”
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Measurement-guided therapeutic-dose prediction using multi-level gated modality-fusion model for volumetric-modulated arc radiotherapy by Changfei Gong, Changfei Gong, Changfei Gong, Yuling Huang, Yuling Huang, Yuling Huang, Junming Jian, Junming Jian, Junming Jian, Wenheng Zheng, Wenheng Zheng, Wenheng Zheng, Xiaoping Wang, Xiaoping Wang, Xiaoping Wang, Shenggou Ding, Shenggou Ding, Shenggou Ding, Yun Zhang, Yun Zhang, Yun Zhang

“…The purpose of this study is to develop a novel deep learning model for measurement-guided therapeutic-dose (MDose) prediction from head and neck cancer radiotherapy data.MethodsThe enrolled 310 patients underwent volumetric-modulated arc radiotherapy (VMAT) were randomly divided into the training set (186 cases, 60%), validation set (62 cases, 20%), and test set (62 cases, 20%). …”
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Non-typhoidal Salmonella among slaughterhouse workers and in the pork value chain in selected districts of Uganda by Velma Kivali, Velma Kivali, Velma Kivali, Kristina Roesel, Kristina Roesel, Ian Dohoo, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, James Katamba Bugeza, James Katamba Bugeza, Jolly Justine Hoona, Denis Rwabiita Mugizi, Denis Rwabiita Mugizi, Clovice Kankya, Sinh Dang-Xuan, Sinh Dang-Xuan, Istvan Szabo, Uwe Rösler, Anika Friese, Elizabeth A. J. Cook, Elizabeth A. J. Cook

“…Antimicrobial resistance profiles were determined using tube microdilution and Sensititre® EUVSEC3® plates. Semi- structured questionnaires with 35 questions were used to collect data on demographics, work related risk factors and activities outside the slaughterhouse.Results and discussionOverall NTS prevalence was 19.2% (365/1899). …”
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Effectiveness of a multicomponent intervention to promote physical activity during the school day: rationale and methods of the MOVESCHOOL study by Francisco J. Bandera-Campos, Francisco J. Bandera-Campos, Alberto Grao-Cruces, Alberto Grao-Cruces, Daniel Camiletti-Moirón, Daniel Camiletti-Moirón, Fátima Martín-Acosta, Fátima Martín-Acosta, Raúl Muñoz-González, María González-Pérez, María González-Pérez, Abel Ruiz-Hermosa, Abel Ruiz-Hermosa, Miguel Vaquero-Solís, Miguel Vaquero-Solís, Carmen Padilla-Moledo, Carmen Padilla-Moledo, David Sánchez-Oliva, David Sánchez-Oliva, David Sánchez-Oliva

“…Additionally, qualitative data were gathered through semi-structured individual interviews and focus groups, and information will be evaluated with thematic analysis.DiscussionThe MOVESCHOOL study represents a pioneering effort in Spain, being the first of its kind to evaluate the effectiveness of a multicomponent programme in secondary schools. …”
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Cross-species comparison of rodent and human decision-making in the Iowa Gambling Task in select neurological and psychiatric disorders: translational approach to examine age- and... by Varsha Singh, Manjari Tripathi, Sarat P. Chandra, Rohit Verma, Sushil Kumar Jha, Harvinder Singh Chhabra, Mrinmoy Chakravarty, Mrinmoy Chakravarty, Shambhovi Mitra, Indupriya B, Ankit Jha, Sakshi Sharma, Jyotsna Pandey, Divyanshi Pandey, Insha Shamshad, Ekta Ahlawat, Titli Saha, Chloé César, Suman Jain

“…This non-analogous structural–functional mapping of brain regions and cognitive deficits result in rodent models that fail to establish causal links of brain pathophysiology and clinical conditions, and the model remains a poor depiction of cognitive deficits experienced by humans. …”
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High-Dose Ceftriaxone in Elderly Patients with Enterococcal Infective Endocarditis: Population Pharmacokinetics of Free Ceftriaxone and Dose Optimization by Beatriz Fernández Rubio, Fernando Docobo Pérez, Laura Herrera Hidalgo, Luis Eduardo López-Cortés, Rafael Luque Márquez, José Manuel Lomas Cabezas, Luis Fernando López-Cortés, Marta Mejías Trueba, Ana Belén Guisado Gil, Alicia Gutiérrez Valencia, Arístides de Alarcón González, María Victoria Gil Navarro

“…A two-compartment model with first-order absorption and elimination best described the data. Ceftriaxone one-hour infusions only achieved the minimum PK/PD target when the 2 g/12 h regimen was tested. …”
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Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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Distinct subnetworks of the mouse anterior thalamic nuclei by Houri Hintiryan, Mitchell Rudd, Sumit Nanda, Adriana E. Gutierrez, Darrick Lo, Tyler Boesen, Luis Garcia, Jiandong Sun, Christian Estrada, Hyun-Seung Mun, Seita Yamashita, Yeji E. Han, Ian Bowman, Lin Gou, Chunru Cao, Jennifer Gonzalez, Keivan Moradi, Qiuying Zhao, Inga Yenokian, Aishwarya Dev, Brian Zingg, Hanpeng Xu, Qing Xue, Muye Zhu, Lijuan Liu, Xin Chen, Zhixi Yun, Hanchuan Peng, Nicholas N. Foster, Hong-Wei Dong

“…Therefore, the ATN provide a promising avenue to investigate the relationship between structural and functional complexity with neuron type diversity. …”
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Unearthing the climate history of the Atacama Desert in northern Chile – deep drilling in two clay pans of the Coastal Cordillera by V. Wennrich, J. Diederich-Leicher, B. N. Blanco-Arrué, B. N. Blanco-Arrué, C. Büttner, S. Buske, E. Campos Sepulveda, T. Dunai, J. Feller, E. Galego, A. Hasberg, N. Leicher, D. A. López, J. Maldonado, A. Medialdea, A. Medialdea, L. Ninnemann, L. Ninnemann, R. Perryman, J. C. Ríos-Contesse, B. Ritter, S. Scheidt, B. Vargas-Machuca, P. Yogeshwar, P. Yogeshwar, M. Melles

“…</p> <p>Lithological data and downhole-logging results of the deep-drilling operations reveal strong heterogeneities in the sediment composition that presumably can be traced back to major climatic and/or tectonic shifts in the catchments of the clay pans. …”
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The changing face of the Arctic: four decades of greening and implications for tundra ecosystems by Gerald V. Frost, Uma S. Bhatt, Matthew J. Macander, Logan T. Berner, Donald A. Walker, Martha K. Raynolds, Rúna Í. Magnússon, Annett Bartsch, Jarle W. Bjerke, Jarle W. Bjerke, Howard E. Epstein, Bruce C. Forbes, Scott J. Goetz, Elizabeth E. Hoy, Elizabeth E. Hoy, Stein R. Karlsen, Timo Kumpula, Trevor C. Lantz, Mark J. Lara, Efrén López-Blanco, Paul M. Montesano, Paul M. Montesano, Christopher S. R. Neigh, Ingmar Nitze, Kathleen M. Orndahl, Taejin Park, Taejin Park, Gareth K. Phoenix, Adrian V. Rocha, Brendan M. Rogers, Gabriela Schaepman-Strub, Hans Tømmervik, Mariana Verdonen, Mariana Verdonen, Alexandra Veremeeva, Anna-Maria Virkkala, Christine F. Waigl

“…Here we review the evolving story of Arctic greening, and synthesize long-term spaceborne records of NDVI, climatic data, field observations, and the knowledge base of Arctic residents to place the last four decades of Arctic environmental change in context, and establish expectations and research priorities for the coming decade. …”
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Features of the Circulation of ARVI Pathogens During of Emergence and Widespread of SARS-CoV-2 in the 2018–2021 by E. I. Burtseva, L. V. Kolobukhina, O. L. Voronina, A. V. Ignatjeva, E. A. Mukasheva, A. D. Panova, E. L. Feodoritova, K. G. Krasnoslodotsev, S. V. Trushakova, L. N. Merkulova, I. N. Khlopova, N. V. Breslav, N. N. Ryzhova, M. S. Kunda, E. I. Aksenova, R. V. Vartanyan, L. B. Kisteneva, O. A. Burgasova, A. G. Rosatkevich, I. S. Kruzhkova, M. V. Bazarova, S. V. Smetanina, N. A. Tsvetkova, Yu. S. Levochkina, M. V. Kozlova, D. O. Korostin, E. I. Botsmanov

“…To identify the features of the structure of ARVI during the emergence and widespread spread of SARS-CoV-2. …”
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Explaining the Earnings Management Prediction Model Using the Hybrid of Machine Learning Methods by Hassan Hassani, Esfandiar Malekian Kallehbasti, Yahya Kamyabi

“…In addition, the results indicated that the most important features for prediction are related to the auditor's features in the first place and then to the features of the company's ownership structure. In other words, investors should pay a lot of attention to the features of the auditor and the ownership structure of companies in predicting earnings management. …”
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The Pathology of Insistence on Indirect Disclosure of Operating Cash Flows by Esmail Farzaneh Kargar, Mehdi Bahar Moghadam

“…The method used is three separate surveys conducted through structured questionnaires on random samples of private investors (384 people), financial managers (201 people), and auditors (265 people). …”
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Debonding Analysis Model and Experimental Investigations on FRP Plates Reinforced SHCC Beams Under Three-point Bending by HU Jihong, SUN Mingqing, WANG Yingjun, CHEN Jianzhong, HUANG Wei

“…The results showed reasonable agreement with the experimental data, indicating that the approach can be applied to the analysis of this type of new civil engineering structure.…”
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Ordovician conodonts of the Katkoyeh formation in the Kuh-e-Bonorg section, Kalmard Horst (west of Tabas) by Mohammad Nezhadabbas, Abbas Ghaderi, Hadi Jahangir, Ali Reza Ashouri

“…The Katkoyeh formation with 214.8 meter thickness is divided into three lithostratigraphic members including the Lower Sandstone (mostly quartzarenite to litharenite), Middle Shale (red to green shales interbedded with some dolomitic and calcareous sandstones, in laminated wavy stromatolite structure at the base) and Upper Carbonate (limestones, dolostones and marls). …”
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Right atrial strain in Anderson–Fabry disease by Rosa Lillo, Rosa Lillo, Alessio Cianci, Maria Chiara Meucci, Giulia Iannaccone, Giulia Iannaccone, Claudio Di Brango, Filippo Tusa, Mario Marsilia, Gaetano Antonio Lanza, Gaetano Antonio Lanza, Antonella Lombardo, Antonella Lombardo, Francesco Burzotta, Francesco Burzotta, Francesca Graziani

“…BackgroundTo date, only limited data are available on right atrium (RA) morphofunctional remodeling in Fabry disease (FD).PurposeWe aimed to investigate RA structural and functional remodeling in patients with FD vs. healthy controls using 2D speckle tracking echocardiography (STE) and to explore whether any differences exist in FD patients with and without left ventricular hypertrophy (LVH).MethodsWe prospectively enrolled patients with FD and controls matched for age, sex, and cardiovascular risk factors. …”
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Multi-omics insights into functional alterations of the liver in growth-retarded offspring: transcriptomic, epigenetic and metabolomic profiles by Qun Lan, Sui Liufu, Xin Xu, Bohe Chen, Wenwu Chen, Kaiming Wang, Caihong Liu, Lanlin Xiao, Xiaolin Liu, Lei Yi, Jingwen Liu, Qiuchun Deng, Haiming Ma, Meng Kang

“…Finally, integrative analysis of RNA-seq and ATAC-seq data revealed several differentially accessible regions (DARs), which were annotated to the genes ACSL3, ITGA11, COL6A3, CYP2C49, and STXBP3. …”
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Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch... by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

“…Baseline mental health data (Structured Clinical Interview for DSM-5, SCID-5RV), and secondary biomedical outcomes (HbA1c; glucose time in range; TIR) and person-reported outcome measures (PROM: Diabetes Eating Problems Survey-Revised, DEPS-R; Eating Disorder Examination Questionnaire Short, EDE-QS; Type 1 Diabetes Distress Scale, T1DDS; Generalised Anxiety Disorder Assessment, GAD-7; Patient Health Questionnaire, PHQ-9; Impact of Diabetes Profile, DIDP) were collected. …”
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Hemoglobin state-flux: A finite-state model representation of the hemoglobin signal for evaluation of the resting state and the influence of disease. by Randall L Barbour, Harry L Graber, San-Lian S Barbour

“…Inspection of the coefficient arrays reveals that they are governed predominantly by first-order rate processes, and that each array class exhibits preferred structure that is mainly independent of the others. …”
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