Urban pertussis epidemiological patterns in a highly vaccinated megacity: Policy impacts and control strategies in Chongqing, China, 2005-2024 by Rui Shen, Jiawei Xu, Yugang Li, Jianxing Yu, Na Sun, Zilu Xu, Xueying Xu, Xiao Liu, Yang Liu, Bosong Li, Li Qi, Luzhao Feng

“…Methods: Using population-based surveillance data (2005-2024) from Chongqing (population 32.1 million; DTP3 coverage >97%), we conducted hierarchical Bayesian spatial modeling and age-structured Susceptible-Infected-Recovered-Vaccinated transmission analysis. …”
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Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome by Cristina Alonso, Alicia García-Culebras, Valentina Satta, Inés Hernández-Fisac, Álvaro Sierra, José A. Guimaré, Ignacio Lizasoain, Javier Fernández-Ruiz, Onintza Sagredo

“…However, the levels of endogenous IgG in this brain structure were significantly elevated in DS mice compared to controls, directly indicating the occurrence of extravasation into the brain parenchyma and indirectly that the BBB in DS mice may be relatively affected, a fact confirmed by the reduction in the levels of BBB-related proteins such as ZO-1 in these mice. …”
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A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response by Xiao‐Ming Lyu, Xiao‐Wei Zhu, Manli Zhao, Xian‐Bo Zuo, Zhong‐Xi Huang, Xiao Liu, Tao Jiang, Xue‐Xi Yang, Xin Li, Xiao‐Bing Long, Jian‐Guo Wang, Jin‐Bang Li, Ming‐Yu Han, Shuang Wang, Teng‐Fei Liu, Bo Zhang, Tao Sun, Zhi Cheng, Mo‐Chang Qiu, Lei Dong, Lu Zheng, Long‐Cheng Zhang, Jia‐Hong Wang, Gan‐Guan Wei, Kaitai Yao, Qian Wang, Hou‐Feng Zheng, Xin Li

“…Abstract The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes. …”
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Mapping the Filamentary Nebula of NGC 1275 with Multiwavelength SITELLE Observations by Carter Lee Rhea, Julie Hlavacek-Larrondo, Marie-Lou Gendron-Marsolais, Benjamin Vigneron, Megan Donahue, Auriane Thilloy, Laurie Rousseau-Nepton, Mar Mezcua, Norbert Werner, Jorge Barrera-Ballesteros, Hyunseop Choi, Alastair Edge, Andrew Fabian, G. Mark Voit

“…The filamentary nebula encompassing the central galaxy of the Perseus Cluster, NGC 1275, is a complex structure extending dozens of kiloparsecs from NGC 1275. …”
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Social networks, environmental, and individual factors associated with COVID-19 vaccination and booster uptake– The prospective PRIME cohort study by Céline J.A. van Bilsen, Lisanne C.J. Steijvers, Stephanie Wagner, Demi M.E. Pagen, Senne M.C.E. Wijnen, Kevin Konings, Christian J.P.A. Hoebe, Annemarie Koster, Nicole H.T.M. Dukers-Muijrers

“…Methods: In the PRIME longitudinal cohort study, we used online questionnaires to collect baseline data at the end of 2021, including participants' COVID-19 vaccination status and various factors, i.e., structural and functional social network characteristics (interpersonal factors), societal (social and physical living environment) community (work and social participation), and individual (sociodemographics, health) factors. …”
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Open Innovation the Impact of Social Capital on Tourism Growth Through the Mediating Role of Open Innovation (Case study: The municipality of Khomam County) by Seyed Hamed Hashemi, Hossein Poorghasem

“…This research is applied in terms of purpose and is survey-based for data collection. Moreover, from a methodological perspective, it employs a correlational design; the data collection tool used in this study was a questionnaire, rated using a Likert scale, and its reliability was assessed using Cronbach's alpha. …”
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency by A. Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B. Hillegass, Francisco S. Sy, Brian Melancon, H. Timothy Bunnell, Lucio Miele, Mary Helen Mays, Joseph Keawe‘aimoku Kaholokula, Elizabeth S. Chen, Karen M. Crowley, Indra Neil Sarkar, Susan L. Santangelo, Clifford J. Rosen, Jeremy Harper, David Bard, William Beasley, Sally L. Hodder

“…Methods: We developed an organizational structure across the IDeA-CTRs to improve research productivity in resource-challenged areas of the U.S. …”
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Echoes of 1816: microbial footprints in heritage artifacts from Argentina’s museum of independence by Daniel Gonzalo Alonso-Reyes, Daniel Gonzalo Alonso-Reyes, Fátima Silvina Galván, Fátima Silvina Galván, Natalia Noelia Alvarado, Natalia Noelia Alvarado, María Cecilia D’Arpino, María Cecilia D’Arpino, Luciano José Martinez, Luciano José Martinez, Hernán José Esquivel, Cecilia Aymara Gallardo, María Julia Silva Manco, María Julia Silva Manco, Virginia Helena Albarracín, Virginia Helena Albarracín, Virginia Helena Albarracín, Virginia Helena Albarracín

“…This study shows the importance of incorporating microbiological data into conservation protocols. By characterizing the artifact-associated microbiota, we contribute to the emerging field of heritage microbiology and future bio-informed preservation strategies.…”
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Senescence-induced p21high macrophages contributed to CD8+ T cells-related immune hyporesponsiveness in kidney transplantation via Zfp36/IL-27 axis by Tingting Zhu, Qixia Shen, Lingling Shen, Yucheng Wang, Bochen Zhu, Lifeng Ma, Shi Feng, Cuili Wang, Sijing Yan, Jingyi Li, Zhimin Chen, Jingyi Zhou, Hongfeng Huang, Bingjue Li, Zhouji Shen, Qian Wang, Jianwei Wang, Wilfried Gwinner, Irina Scheffner, Song Rong, Bing Yang, Junwen Wang, Hermann Haller, Xiaoping Han, Guoji Guo, Zhinan Yin, Jin Jin, Hui-Yao Lan, Jianghua Chen, Hong Jiang

“…Age-related functional and structural changes in the immune system have been observed, yet the precise influence of aged immunity on kidney transplant remains unclear. …”
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Exploring ultrasound and electromyography for carpal tunnel syndrome diagnosis: a comprehensive comparative study and implications for occupational medicine by Salem Braham, Salem Braham, Amen Moussa, Amen Moussa, Marwa Bouhoula, Marwa Bouhoula, Nihel Ben Meriem, Nihel Ben Meriem, Ichraf Annen, Ichraf Annen, Ghazi Sakly, Ghazi Sakly, Asma Chouchane, Asma Chouchane, Malek Ben Abdelkader, Malek Ben Abdelkader, Asma Aloui, Asma Aloui, Imène Kacem, Imène Kacem, Maher Maoua, Maher Maoua, Houda Kalboussi, Houda Kalboussi, Olfa Elmaalel, Olfa Elmaalel, Houda Mhabrech, Houda Mhabrech, Souheil Chatti, Souheil Chatti, Aicha Brahem, Aicha Brahem

“…BackgroundTo assess the contribution of ultrasound in diagnosing occupational carpal tunnel syndrome (CTS), compare it with electromyography (EMG) results, and evaluate the ultrasound characteristics of CTS patients.MethodsA nine-month cross-sectional study (January–September 2021) involved CTS patients and a control group, utilizing a structured form for data collection. EMG was performed on the patient group (‘cases’) and ultrasound examinations were conducted on both groups. …”
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Longitudinal analysis of lifestyle risk factors, nutrition status and drivers of food choice among urban migrants in Ulaanbaatar, Mongolia, and Almaty, Kazakhstan: a formative stud... by Sabri Bromage, Shamil Tazhibayev, Xin Zhou, Chang Liu, Enkhtsetseg Tserenkhuu, Oksana Dolmatova, Munkhbat Khishignemekh, Leyla Musurepova, Wusigale, Soninkhishig Tsolmon, Enkhjargal Tsendjav, Davaasambuu Enkhmaa, Rajesh Kumar Rai, Bayarmaa Enkhbat, Bilige Menghe, Davaasambuu Ganmaa

“…Design: We collected panel data on household structure, drivers of food choice, nutrition knowledge and diverse measures of nutrition status and lifestyle risk from urban migrants at 0, 3, 6 and 9 months using harmonised methodology in two cities. …”
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Two novel plasmids harbouring the multiresistance gene cfr in porcine Staphylococcus equorum by Ning Xie, Tengfei Ma, Yuan Gao, Jiani Fu, Chune Tan, Zheng Wang, Zhuo Wang, Henrike Krüger-Haker, Andrea T. Feßler, Congming Wu, Jianzhong Shen, Stefan Schwarz, Yang Wang

“…De novo hybrid assembly was performed by Unicycler. Genomic data were assessed by in silico prediction and bioinformatic tools. …”
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Costs of biomarker testing in advanced non‐small cell lung cancer: a global study comparing next‐generation sequencing and single‐gene testing by Umberto Malapelle, Chien‐Chin Chen, Enrique deÁlava, Paul Hofman, Daniel Kazdal, Tae‐Jung Kim, Tony Kiat Hon Lim, Aleš Ryška, Angelica A Saetta, Ed Schuuring, Giancarlo Troncone, Michele Biscuola, Yi‐Lin Chen, Gek San Tan, Charles Hugo Marquette, Maria Michelli, Arja terElst, Hana Vošmiková, Joshua Kapp, Sebastian Gonzalez‐McQuire, Andromachi Giannopoulou, Jean Marie Franzini, Victoria Lucia Rabsiun Aramburu, Anna Baggi, Albrecht Stenzinger

“…This observational study was conducted across 10 pathology centers in 10 different countries worldwide. Biomarker data collected via structured questionnaires (1 January–31 December 2021) were used to feed micro‐costing analyses for three scenarios [‘Starting Point’ (SP; 2021–2022), ‘Current Practice’ (CP; 2023–2024), and ‘Future Horizons’ (FH; 2025–2028)] in both a real‐world model, comprising all biomarkers tested by each center, and a standardized model, comprising the same sets of biomarkers across centers. …”
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Outpatient Virtual Care Among People Living With and Beyond Cancer From Culturally and Linguistically Diverse Backgrounds in Australia: A Protocol for a Realist Evaluation by Prince Peprah, Sagda Osman, Rebecca Mitchell, Ashfaq Chauhan, Ramya Walsan, Maryam Sina, Bronwyn Newman, Nadine El‐Kabbout, Jan Mumford, Emilie Francis‐Auton, Elizabeth Manias, Virginia Mumford, Kate Churruca, Michelle Moscova, Natalie Taylor, Craig Nelson, Alexander Cardenas, Robyn Clay‐Williams, Jeffrey Braithwaite, Reema Harrison

“…Patients and the public are also represented as Project Steering Group members who will inform the data collection processes, development, and refinement of our program theory.…”
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Parasitic infection prevalence in tuberculosis patients and their household contacts in the Littoral Region of Cameroon by Lucy Cho Nchang, Chefor Magha, Patience Agwa Fonong, Narcisse Victor Tchamatchoua Gandjui, Nancielle Mbiatong Tchatat, Desmond Akumtoh Nkimbeng, Frank Noel Nietcho, Juluis Visnel Foyet, Fanny Fri Fombad, Tatiana Djikeussi Katcho, Jerome Fru Cho, Achim Hoerauf, Manuel Ritter, Samuel Wanji

“…Methodology: This was a hospital based cross-sectional descriptive study carried out with newly diagnosed active tuberculosis (TB) patients and their household contacts in the Littoral Region of Cameroon. Socio-demographic data and associated factors were collected using structured questionnaires. …”
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Undertriage in geriatric trauma: insights from a multicentre cohort study by Daniel Anthony Koch, Lars Becker, Uwe Schweigkofler, Paul Hagebusch, Philipp Faul, Christian Waydhas, Florian Pavlu, Markus Baacke, Caspers Michael, Valentin Clemens, Helena Duesing, Matthias Froehlich, Sebastian Imach, Kai-Oliver Jensen, Christian Kleber, Annette Keß, Gerrit Matthes, Andre Nohl, Orkun Oezkurtul, Thomas Paffrath, Vera Pedersen, Kai Sprengel, Philipp Stoermann, Heiko Trentzsch, Rolf Lefering, Dan Bieler, Lisa Hackenberg, The Committee on Emergency Medicine, Intensive Care and Trauma Management (Sektion NIS) of the German Trauma Society (DGU) Germany

“…Abstract Background With the aging population, the number of geriatric trauma patients continues to rise, posing significant challenges for emergency care and trauma management. Structured trauma team activation (TTA) protocols aim to provide timely and adequate treatment for severely injured patients. …”
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Development and evaluation of a web-based diet quality screener for vegans (VEGANScreener): a cross-sectional, observational, multicenter, clinical study by Tooba Asif, Anna Ouřadová, Ainara Martínez Tabar, Vanessa Bullón-Vela, Sandra Müller, Joelina Dietrich, Vanessa Keller, Marina Heniková, Eliška Selinger, Isabelle Herter-Aeberli, Maria Wakolbinger, Willem De Keyzer, Willem De Keyzer, Wendy Van Lippevelde, Monika Cahová, Leonie H. Bogl, Leonie H. Bogl, Marek Kuzma, Maira Bes-Rastrollo, Maira Bes-Rastrollo, Stefaan De Henauw, Markus Keller, Selma Kronsteiner-Gicevic, Selma Kronsteiner-Gicevic, Eva Schernhammer, Eva Schernhammer, Jan Gojda

“…Secondary outcomes will include analysis of dietary data, metabolomics, and microbiomes in all participants. …”
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Harnessing community knowledge and actions to strengthen rabies control programs in East Nusa Tenggara, Indonesia by Yoany Maria Vianney Bita Aty, Endang Puji Astuti, Florentianus Tat, Wanti Wanti, Johanis J. Pitreyadi Sadukh, Irwan Budiana, Aemilianus Mau, Irfan Irfan, Riny Pujiyanti, Wiendra Waworuntu, Andi Leny Susyanti, Nirmala Ahmad Ma’ruf, Luna Amalia

“…Qualitative data, obtained through in-depth interviews and focus group discussions, were thematically analyzed using the context, input, process, and product evaluation model to explore stakeholder coordination, community engagement, and systemic challenges. …”
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Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway by Ju Huang, Ju Huang, Jing Li, Jing Li, Zhijun Geng, Zhijun Geng, Lixia Yin, Lixia Yin, Minzhu Niu, Qingqing Li, Qingqing Li, Xinyue Liu, Xinke Cheng, Xiaofeng Zhang, Xue Song, Xue Song, Yueyue Wang, Yueyue Wang, Lian Wang, Lugen Zuo, Jianguo Hu, Jianguo Hu

“…Background and aimsPatients with Crohn’s disease (CD) exhibit excessive apoptosis of intestinal epithelial cells (IECs), which contributes to damage to the intestinal barrier structure and function, thereby playing a role in the progression of colitis. …”
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Understanding the future of dengue in Malaysia: Assessing knowledge, attitude, and homeowner practices in mitigating climate-driven risks [version 1; peer review: 2 approved] by Sapna Shridhar Patil, Izzah Athirah Rosli, Fatin Norhasny Leman, Nur Hasnah Ma’amor, Nor Asiah Muhamad, Kulankara Balan Venugopalan, Prabal Bhargava, Mahalingam Dinesh, Weng Keong Yau, Chai Hong Yeong, Eng Hwa Wong, Arasarethinam Mugilarasi, Ameya Ashok Hasamnis, Imam Shaik, Chung Yeng Looi, Pei Pei Chong, Priya Madhavan, Lei Hum Wee, Anitha Ponnupillai, Jo Ann Andoy-Galvan, Yin How Wong

“…A representative sample of 1,636 residents was calculated using the Krejcie and Morgan formula, and stratified random sampling was used to ensure proportional representation across the various floors of each PPR community apartment block. Data were collected using a structured questionnaire adapted from a validated Malay version. …”
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