Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease by Da-Ya Zhang, Da Li, Shi-Ju Chen, Li-Jun Zhang, Xu-Li Zhu, Fa-Di Chen, Chen Chen, Qi Wang, Yiping Du, Jian-Xin Xiong, Shi-Mei Huang, Xiao-Dong Zhang, Yan-Ting Lv, Fan Zeng, Run-Xiang Chen, Xianfeng Huang, Fengjiao Mao, Shuo Zhou, Qicen Yao, Yuliang Huang, Runyu Chen, Ying Mo, Yunqian Xie, Yue-Hong Jiang, Zhai Chen, Cui-Yi Mo, Jia-Jia Chen, Fei-Hu Bai

“…Combined analysis of metabolomic and metagenomic data achieved high diagnostic accuracy for MAFLD and hepatic steatosis severity (AUC = 0.93). …”
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Correlates of duration between initial drug use and first drug injection among people who inject drugs in Iran, 2020 by Zahra Abdolahinia, Zahra Jaafari, Ali Karamoozian, Soheil Mehmandoost, Nima Ghalekhani, Mehrdad Khezri, Ghazal Mousavian, Mostafa Shokoohi, Ali Mirzazadeh, Ali Akbar Haghdoost, Mohammad Karamouzian, Mohammad Mehdi Gooya, Samaneh Akbarpour, Hamid Sharifi, Fatemeh Tavakoli

“…Policymakers should prioritize evidence-based, multi-faceted approaches that target both individual and structural factors to delay or prevent the transition to injection drug use and reduce associated health risks.…”
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Understanding Care‐Seeking Behavior for Reproductive Tract Infections Among Afghan Women: A Cross‐Sectional Study by Cecilia Acuti Martellucci, Nooria Mohammady, Fawzia Negin, Sayed Hamid Mousavi, Adriana Viola Miranda, Husna Safa, Bibi Qudsia Qasimi, Khaterah Mosavi, Basira Bek, Alisina Azimi, Zahra Annabi, Saddiqa Noorzai, Aabidullah Rahimee, Taha Balaghat, Fatema Rezaie, Fardına Temory, Mirwais Ramozi, Mosè Martellucci, Rahila Bek, Shabanah Noorzai, Madina Niro, Husna Sultani, Palwasha Farooqi, Ehsan Shayan, Mohammadgul Zhwand, Qasem Rezaee, Farzana Torgani, Bibi Shakiba Hussaini, Shaqaiq Akhtiyari, Farah Qaderi, Shohra Qaderi

“…ABSTRACT Background In Afghanistan, providing care for reproductive tract infections (RTIs) is challenging, among other factors, due to the extreme scarcity of reliable data. To address this gap, the present study investigates symptoms, potential risk factors, knowledge, and care‐seeking behavior in the largest sample of women to date. …”
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‘It’s the perfect storm’: why are people with eating disorders at risk of suicide? A qualitative study by Una Foye, Saakshi Kakar, Niamh McNamara, Agnieszka Musial, Tom Jewell, Jessica R. Griffiths, Carol Kan, Gerome Breen, Rachel Rowan Olive, T. Suratwala, Aman Sidhu, Lizzie Mitchell, George Mycock, Katie Graden, Saskia Evans Perks, Elia Chitwa, Holly Whitehead, Ulrike Schmidt, Rina Dutta, Moritz Herle

“…Methods Using a qualitative design, we conducted semi-structured interviews with people with lived experience of an ED (n = 30), and clinicians who work with people with EDs (n = 19). …”
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Adherence to Mediterranean diet in Moroccan school-age adolescents: sociodemographic, socioeconomic and lifestyle determinants by Halima Belaoufi, Sanaa El-Jamal, Khadija Sahel, Abdelghani Aboukhalaf, Firdaous Friki, Hamid Chamlal, Jamila Elbiyad, Soumaya Atouife, Abdellah El Habazi, Rekia Belahsen

“…Material and methods A cross-sectional survey was conducted in a school setting among 386 students (148 boys and 238 girls), aged 14 to 18 years, randomly selected and from different socioeconomic strata. A structured questionnaire was used to collect sociodemographic, socioeconomic and lifestyle data. …”
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Knowledge, attitudes, and practices of people living in artisanal mining areas on water pollution in Siguiri, Guinea, 2023 by Aly Badara Toure, Aly Badara Toure, Mariama Sadjo Diallo, Mariama Sadjo Diallo, Sidikiba Sidibe, Sidikiba Sidibe, Salifou Talassone Bangoura, Salifou Talassone Bangoura, Fassou Mathias Grovogui, Fassou Mathias Grovogui, Fassou Mathias Grovogui, Maladho Diaby, Maladho Diaby, Mohamed Aly Bangoura, Yamoussa Youla, Mory Kourouma, Alexandre Delamou, Alexandre Delamou, Alexandre Delamou

“…The objective of this study was to analyze the knowledge, attitudes, and practices (KAP) of the population regarding water pollution in the mining areas of Siguiri, Guinea.MethodsA cross-sectional study was conducted from May 15 to June 15, 2023, on the population of Doko, Siguiri. Data were collected using a structured questionnaire that assessed knowledge, attitudes, and practices related to water pollution in artisanal mining areas. …”
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Cluster Candidates with Massive Quiescent Galaxies at z ∼ 2 by Tomokazu Kiyota, Makoto Ando, Masayuki Tanaka, Alexis Finoguenov, Sadman Shariar Ali, Jean Coupon, Guillaume Desprez, Stephen Gwyn, Marcin Sawicki, Rhythm Shimakawa

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Population-based cross-sectional seroprevalence study of SARS-CoV-2 infection in urban residential areas in Ghana by John H Amuasi, Aurélia Souares, Eva Lorenz, Wibke Loag, Anthony Afum-Adjei Awuah, Sylvester Newton, Christian Obirikorang, Evans Asamoah Adu, Eric Ebenezer Amprofi Boham, Alexander Owusu Boakye, Hakim Alani, Nana Safi Almoustapha, James Deke, Welbeck Odame Dzadey, Louis Adu-Amoah, Sally-Ann Kroduah, Mary Ama Grant, Gracelyn Asare, Amos Amoako-Adusei, Jenny Kettenbeil, Yaw Adu Sarkodie, Ebenezer Oduro, Alfred E Yawson, Stephen Apanga, Rose Odotei Adjei, Austin Gideon Adobasom Anane, Oumou Maiga Ascofare, May Jurgen, Nicole S Struck

“…Bayesian models with poststratification weighting of the demographic structure of the sample population were used for seroprevalence estimates, accounting for the uncertainty of diagnostic assay in a hierarchical model. …”
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Enhancing regeneration and functionality of excitable tissues via integrating bioelectronics and bioengineered constructs by Zijie Meng, Bingsong Gu, Cong Yao, Jiaxin Li, Kun Yu, Yi Ding, Pei He, Nan Jiang, Dichen Li, Jiankang He

“…These interactions enable precise data acquisition and localized modulation of cell and tissue functionalities through intricately designed electronic components according to physiological needs. …”
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Patient and healthcare professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: qualitative study of the CATHETER II trial by John Norrie, Graeme Maclennan, David Cooper, Paul Little, Peter Murchie, Phyo Kyaw Myint, Mohamed Abdel-fattah, Mary Kilonzo, Muhammad Imran Omar, Diana Johnson, Sara J Maclennan, James Ndow, Graham Scotland, Amanda Young, Seonaidh Cotton, Nikesh Thiruchelvam, Catherine Paterson, Lynda Constable, Hashim Hashim, Sheela Tripathee, Konstantinos Dimitropoulos, Suzanne Evans, Karen Powell, James Hugh Larcombe

“…Data were analysed using the Theoretical Framework of Acceptability and Theoretical Domains Framework. …”
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Readiness for scale up following effectiveness-implementation trial: results of scalability assessment of the Community Partnership Program for diabetes self-management for older a... by Melissa Northwood, Tracey Chambers, Kathryn Fisher, Rebecca Ganann, Maureen Markle-Reid, Marie-Lee Yous, Ron Beleno, Gary Gaudet, Andrea Gruneir, Helen Leung, Craig Lindsay, Kasia Luebke, Gail Macartney, Ethel Macatangay, Janet MacIntyre, Carolyn MacPhail, William Montelpare, Allan Morrison, Lisa Shaffer, Martha St. Pierre, Frank Tang, Catharine Whiteside

“…Data collection and analysis was informed by the Intervention Scalability Assessment Tool (ISAT); developed to support practitioners and policy makers in conducting systematic assessments of the suitability of health interventions for population scale-up in high-income countries. …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

“…Intensive study of the T6SS structure has led to an understanding of certain issues related to its functional activity, but the exact regulatory mechanisms of E-I protein pair activity remain unclear. …”
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The MaNGA Dwarf Galaxy Sample (MaNDala): Stellar Profiles and Gradients Characterization by M. Cano-Díaz, A. Rodríguez-Puebla, A. C. Robleto-Orús, V. Ávila-Reese, H. M. Hernández-Toledo, J. A. Vázquez-Mata, O. Valenzuela, J. J. González, H. J. Ibarra-Medel, J. C. Clemente-González, L. Pavón-Alvarez

“…We derived robust radial profiles and inner/outer gradients of various stellar population (SP) properties for a sample of 124 bright dwarf galaxies, 10 ^7.53 ≤ M _* / M _⊙ ≤ 10 ^9.06 , from the MaNDala sample, using integral field spectroscopy observations. Given the complex structure of dwarf galaxies, we explored four different methods to derive SP radial profiles: two based on concentric elliptical rings, and the other two exploiting the spatially resolved nature of the data. …”
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A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection? by Francesco Rocco Bertuccio, Nicola Baio, Simone Montini, Valentina Ferroni, Vittorio Chino, Lucrezia Pisanu, Marianna Russo, Ilaria Giana, Elisabetta Gallo, Lorenzo Arlando, Klodjana Mucaj, Mitela Tafa, Maria Arminio, Emanuela De Stefano, Alessandro Cascina, Angelo Guido Corsico, Giulia Maria Stella, Valentina Conio

“…The detection of <i>E. dermatitidis</i> should prompt a comprehensive evaluation, integrating clinical, radiologic, and microbiologic data to guide management. Voriconazole is currently the antifungal agent of choice, though therapeutic thresholds and duration remain undefined. …”
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The haplotype-resolved telomere-to-telomere genome and OMICS analyses reveal genetic responses to tapping in rubber tree by Chaochao Li, Yuan Yuan, Zhiyi Nie, Tingkai Wu, Zhiyuan Wang, Jiangxia Qiao, Zhi Deng, Xiaobo Wang, Dong Xu, Xu Wang, Shuo Cao, Bingqin Li, Zewei An, Wenguan Wu, Zhongxin Jin, Huasun Huang, Wei Hu, Yongfeng Zhou, Han Cheng

“…By integrating transcriptomic and metabolomic data, we reconstruct the rubber biosynthesis pathway and confirm the mevalonate (MVA) pathway as the major carbon source for rapid latex regeneration during tapping. …”
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Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE). by Belinda von Niederhäusern, Gordon H Guyatt, Matthias Briel, Christiane Pauli-Magnus

“…The Delphi process ultimately achieved consensus on structure and content. The framework addresses 5 study stages (concept, planning and feasibility, conduct, analysis and interpretation, and reporting and knowledge translation) and includes the following dimensions: (i) protection of patient safety and rights, (ii) relevance/patient centeredness and involvement, (iii) minimization of bias (internal validity), (iv) precision, (v) transparency/access to data, and (vi) generalizability (external validity) of study results. …”
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“A torch, a rope, a belly laugh”: engaging with the multiple voices of support groups for people living with rare dementia by Paul M. Camic, Emma Harding, Sam Rossi-Harries, Oliver S. Hayes, Mary Pat Sullivan, Lawrence Wilson, Nikki Zimmermann, Roberta McKee-Jackson, Joshua Stott, Nick C. Fox, Catherine J. Mummery, Jonathan D. Rohrer, Jason D. Warren, Rimona S. Weil, Sebastian James Crutch

“…The aim of the present study was to explore and better understand what the concept of support means for people living with different rare dementia (PLwRD) and their care-partners who attend ongoing support groups.MethodsRepresenting seven types of rare dementia, source material was collected from 177 PLwRD and care-partners attending in-person support groups, with the goal of developing research-informed group poems, co-constructed by a facilitating poet. Data were analyzed through a three-step process involving linguistic analysis followed by structured-tabular thematic analysis, relational analysis, and concluded with an online survey about participation in the study.ResultsLinguistic analysis found that co-constructed poems remained faithful to the original source material offered by participants. …”
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Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service by Chiara Ceolin, Stefania Sella, Cristina Simonato, Ester Bukli, Giulia Bano, Valentina Camozzi, Anna Bertocco, Marco Onofrio Torres, Alberta Cecchinato, Martin Diogo, Mor Peleg Falb, Francesca Guidolin, Maria Grazia Rodà, Michele Cannito, Antonio Berizzi, Andrea Venturin, Vito Cianci, Elisa Pala, Mariachiara Cerchiaro, Deris Gianni Boemo, Maria Vittoria Nesoti, Gaetano Paride Arcidiacono, Paolo Simioni, Pietro Ruggieri, Giuseppe Sergi, Sandro Giannini, Marina De Rui, on behalf of the Hip-POS working group

“…Patients were categorized based on anti-fracture treatment (bisphosphonates, Denosumab, anabolic agents) or calcium/vitamin D supplements only. Clinical data, including the Multidimensional Prognostic Index (MPI) and its components, were collected. …”
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Evaluation of diabetes mellitus medication-taking behavior among first- and second-generation Australians of Chinese heritage: A nationwide cross-sectional study by Olumuyiwa Omonaiye, Alemayehu Mekonnen, Christopher Gilfillan, Rosemary Wong, Bodil Rasmussen, Elizabeth Holmes-Truscott, Kevin Mc Namara, Elizabeth Manias, Jerry Lai, Julie Considine

“…Culturally relevant clinical discussion and structured diabetes education may support the development of health promoting medication beliefs potentially supporting optimal medication-taking behavior.…”
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Exploring the phylogenetic framework and trait evolution of Impatiens through chloroplast genome analysis by Wen-Xiang Lan, Qing Mo, Meng-Meng Jin, Yong-Hui Wen, Meng-Qing Yang, Hui Ma, Hai-Quan Huang, Mei-Juan Huang

“…The chloroplast genome of Impatiens exhibited a typical four-part structure, with lengths ranging from 146,987 bp(I. morsei)- 152,872 bp(I. jinpingensis). …”
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