Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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Interface characterization of Cu18150/Al1060/Cu18150 laminated composite produced by combined cast-roll and hot-roll technique by Mahmoud Ebrahimi, Yuchao Zhao, Huisheng Cai, Shokouh Attarilar, Zhengping Shang, Qudong Wang

“…Scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) analyses elucidate the formation of IMCs at the interfaces, with predicted formation sequences influenced by Gibbs free energy data. Electron backscatter diffraction (EBSD) analysis indicates that hot rolling promotes grain refinement in Cu18150, resulting in a homogeneous structure with elongated fine grains, while Al1060 shows nonuniform grain distribution. …”
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Identification and Analysis of <i>KAS II</i>, <i>FAT</i>, <i>SAD</i>, and <i>FAD</i> Gene Families in <i>Hippophae rhamnoides</i> by Alexander A. Arkhipov, Ekaterina M. Dvorianinova, Anastasia A. Turba, Roman O. Novakovskiy, Yury A. Zubarev, Pavel A. Predushchenko, Elizaveta A. Sigova, Daiana A. Zhernova, Elena V. Borkhert, Elena N. Pushkova, Chengjiang Ruan, Nataliya V. Melnikova, Alexey A. Dmitriev

“…Our study aimed to solve this issue using the available genomic sequences and transcriptome data that we obtained. We compared the protein sequences of sea buckthorn with those of <i>Arabidopsis thaliana</i> and checked for the presence of conserved domains. …”
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Differential effects of oral versus intravenous hydrocortisone and dexamethasone on capillary blood glucose levels in adult inpatients − a single centre study by Vaishali Limbachia, Ian Nunney, Daniel J. Page, Hannah A. Barton, Leena K. Patel, Georgia N. Thomason, Stephan L. Green, Kieran F.J. Lewis, Ketan Dhatariya

“…An auto-regressive covariance structure was employed to model correlations between repeated measurements. …”
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Quality of Care of Adult Patients With Allergic Diseases in Urban, Rural, and Remote Primary Care Sites in the Philippines by Carol Stephanie C. Tan-Lim, Robbi Miguel G. Falcon, Jeremiah F. Feliciano, Michael B. Fong MD, Mark Anthony U. Javelosa, Leonila F. Dans, Iris Thiele C. Isip-Tan, Josephine T. Sanchez, Mia P. Rey, Antonio Miguel L. Dans

“…Methods: This was a retrospective review of electronic health records of all adult patients who consulted in the 3 sites from May 2019 to April 2022. Data of adult patients with allergic diseases was extracted from the 3 EHR systems operating across the participating sites using standardized Structured Query Language queries across the 3 systems. …”
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Whole-Genome Resequencing to Identify Selection Signatures Associated with High Fertility in Lüliang Black Goat by Xu Wang, Zhenqi Zhou, Xinrui Chai, Jie Li, Wannian Wang, Zhixu Pang, Lifen Cheng, Caihong Cheng, Liying Qiao, Yangyang Pan, Kaijie Yang, Wenzhong Liu, Jianhua Liu

“…Based on whole-genome resequencing data, this study comprehensively assessed the population structure and genetic diversity of LBG and explored the related genes that affect reproductive performance. …”
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Technical note: Flow cytometry assays for the detection, counting and cell sorting of polyphosphate-accumulating bacteria by C. Bouquet, H. Billard, H. Billard, C. C. Bidaud, J. Colombet, J. Colombet, Y.-T. Chang, J. Artigas, I. Batisson, K. Benzerara, F. Skouri-Panet, E. Duprat, A.-C. Lehours

“…This requires high-throughput methods to characterize their structure and dynamics in ecosystems. A promising strategy is to combine the staining of intracellular polyphosphate granules and their subsequent detection by flow cytometry, enabling rapid data acquisition. …”
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Contextual factors in value-based decision support to enhance health technologies adoption: the case of biosimilars by Maximilian Otte, Maximilian Otte, Maximilian Otte, Zoltán Kaló, Zoltán Kaló, Zoltán Kaló, Hussain Abdulrahman Al-Omar, Meindert Boysen, Yingyao Chen, Ana Paula Beck Da Silva Etges, Ana Paula Beck Da Silva Etges, Guvenc Kockaya, Iñaki Gutierrez-Ibarluzea, Ahmed Mohammed Seyam, Deirdre Mullen, Deirdre Mullen, Hans-Peter Dauben, Hans-Peter Dauben, Hans-Peter Dauben

“…The MCDA framework offers a structured approach to operationalize these principles. …”
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Erythritol as a Next-Generation Sweetener: properties, metabolism, cardiovascular risk and gut health implications – A literature review by Julia Skowrońska-Borsuk, Martyna Narożniak, Adrianna Ewa Pękacka, Bartłomiej Czerwiec, Adam Borsuk, Joanna Katarzyna Pergoł, Malwina Wojtas, Julia Borkowska, Zuzanna Krupa, Julia Sposób

“…However, these findings are inconclusive and require further investigation. Emerging animal data indicate erythritol may modulate gut epithelial structure via microbiota-derived metabolites. …”
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Anti-Migratory Activity of Brazilin Chemodiversification on Breast Cancer Cells by Alberto Hernández-Moreno, Dania A. Nava-Tapia, Miriam D. Zuñiga-Eulogio, Jorge Bello-Martínez, Monserrat Olea-Flores, Tadeo Hernández-Moreno, Mario Ordoñez, Ana E. Zacapala-Gómez, Miguel A. Mendoza-Catalán, Napoleón Navarro-Tito

“…In this study, we isolated brazilin from the heartwood of <i>Haematoxylum brasiletto</i>; then, we performed a semi-synthesis by adding three methyl or acetyl groups to the core structure of brazilin. We confirmed the identity of brazilin and its derivatives by spectroscopic data (¹H NMR and ¹³C NMR) and measured their purity by optical rotation. …”
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An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…Furthermore, the developed fluorescence strategy was controllably applied to PK studies in rats administered intravenous AMP (11.25 mg/kg and 22.50 mg/kg), yielding parameters consistent with clinical data. These findings underscore the potential of CA/EDA-CDs for rapid and accurate AMP detection, addressing the clinical need for a simple and rapid monitoring method.…”
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Orthopaedic Consultation is Associated With Fewer Patient-Perceived Barriers to Total Joint Arthroplasty by Insa Mannstadt, BS, BA, J. Alex B. Gibbons, BA, Troy B. Amen, MD, MBA, Mangala Rajan, PhD, Sarah R. Young, PhD, Henry Tischler, MD, Michael L. Parks, MD, Mark Figgie, MD, Anne Bass, MD, Linda Russell, MD, Bella Mehta, MD, MS, Iris Navarro-Millán, MD, Susan M. Goodman, MD

“…Methods: We performed a post-hoc analysis of questionnaire responses based on data from a previous study that used semi-structured interviews with patients with advanced osteoarthritis. …”
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ASSESSMENT OF THE PSYCHOLOGICAL STATUS OF PATIENTS WITH GYNECOLOGICAL CANCER IN THE PROCESS OF PSYCHOLOGICAL REHABILITATION by E. V. Pestereva, V. A. Chulkova, T. Y. Semiglazova, E. G. Ulrich, O. A. Pestereva

“…Material and methods. 41 patients aged from19 to 45 years with oncogynecological diseases at different stages of treatment were examined. The data of the clinical and psychological interviews were supplemented by the results of psychodiagnostic tests -TOBOL, Hissen questionnaire of somatic complaints, EQRTCQLQ-C30. …”
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Inaccuracies of venous thromboembolism risk assessment and prevention practices among medically ill patients by Brandyn D. Lau, Aditya Bhave, Jennifer C. Yui, Rakhi Naik, Kathryn E. Dane, John Lindsley, Dauryne L. Shaffer, Peggy S. Kraus, Erik H. Hoyer, Elliott R. Haut, Michael B. Streiff

“…Leveraging existing structured data to autopopulate VTE risk assessments can assist providers in improving accuracy. …”
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Observations and Studies on the Transiting Systems HAT-P-36, XO-2 and WASP-76 by Weilong Wang, Shenghong Gu, Xiaobin Wang, Leilei Sun, Byeong-Cheol Lee, Chi-Tai Kwok, Ho-Keung Hui, Jiangpei Dou, Yue Xiang, Dongtao Cao, Fukun Xu

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Mapping the genetic landscape of immune-mediated disorders: potential implications for classification and therapeutic strategies by Vera Fominykh, Alexey A. Shadrin, Alexey A. Shadrin, Alexey A. Shadrin, Piotr Jaholkowski, Julian Fuhrer, Nadine Parker, Erik D. Wiström, Oleksandr Frei, Oleksandr Frei, Olav B. Smeland, Olav B. Smeland, Helga Sanner, Helga Sanner, Helga Sanner, Srdjan Djurovic, Srdjan Djurovic, Srdjan Djurovic, Ole A. Andreassen, Ole A. Andreassen, Ole A. Andreassen

“…ObjectivesBased on clinical, biomarker, and genetic data, McGonagle and McDermott suggested that autoimmune and autoinflammatory disorders can be classified as a disease continuum from purely autoimmune to autoinflammatory with mixed diseases in between. …”
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Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics by Wei Lei, Yan Wu, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Huipin Yuan, Mingzheng Li

“…A 12.6-mm cranial defect was confirmed as a CSDs after 12 weeks, with submicron surface-structured biphasic calcium-phosphate (BCP) implants [consisting of 20% hydroxyapatite and 80% tricalcium phosphate (TCP)] demonstrating significantly higher bone formation (32.2% ± 10.6%) than micron surface-structured TCP (TCP-B) implants (17.8% ± 4.6%, p = 0.0121). …”
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Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features by Peter Novak, MD, PhD, David M. Systrom, MD, Sadie P. Marciano, PA-C, Alexandra Witte, PA-C, Arabella Warren, MD, PhD, Donna Felsenstein, MD, Matthew P. Giannetti, MD, Matthew J. Hamilton, MD, Jennifer Nicoloro-SantaBarbara, PhD, Mariana Castells, MD, Khosro Farhad, MD, David M. Pilgrim, MD, William J. Mullally, MD, Mark C. Fishman, MD, Jeff M. Milunsky, MD, Aubrey Milunsky, MD, Joel Krier, MD

“…Small fiber neuropathy using structural criteria was detected in 64%, and using combined structural and functional criteria in 82%. …”
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Using interactive platforms to encode, manage and explore immune-related adverse outcome pathways by Alexander Mazein, Muhammad Shoaib, Miriam Alb, Christina Sakellariou, Charline Sommer, Katherina Sewald, Kristin Reiche, Patricia Gogesch, Luise A. Roser, Samira Ortega Iannazzo, Sapna Sheth, Susanne Schiffmann, Zoe Waibler, Vanessa Neuhaus, Susann Dehmel, Venkata Satagopam, Reinhard Schneider, Marek Ostaszewski, Wei Gu

“…The map is accessible online at https://imsavar.elixir-luxembourg.org via the MINERVA Platform for browsing, commenting, and data visualization. Our work transforms a graphical illustration of an AOP into a digitally structured and standardized form, featuring precise and controlled vocabulary and supporting reproducible computational analyses. …”
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Results of modern radiation-hygienic surveys of settlements of Bryansk Oblast of the Russian Federation bordering the Republic of Belarus. Part 2: Population’s food preferences (di... by I. K. Romanovich, A. B. Bazyukin, A. A. Bratilova, G. Ya. Bruk, K. V. Varfolomeeva, E. A. Drozdova, T. V. Zhesko, M. V. Kaduka, T. A. Kormanovskaya, O. S. Kravtsova, A. V. Kudryashov, A. A. Ladik, V. A. Lalayan

“…The second part of the study presents structure of population’s food preferences (diet). …”
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