Genomic landscape of diffuse glioma revealed by whole genome sequencing by Ben Kinnersley, Josephine Jung, Alex J. Cornish, Daniel Chubb, Ross Laxton, Anna Frangou, Andreas J. Gruber, Amit Sud, Giulio Caravagna, Andrea Sottoriva, David C. Wedge, Thomas Booth, Safa Al-Sarraj, Samuel E. D. Lawrence, Erminia Albanese, Giulio Anichini, David Baxter, Alexandros Boukas, Yasir A. Chowdhury, Pietro D’Urso, Robert Corns, Andrew Dapaah, Ellie Edlmann, Fay Greenway, Paul Grundy, Ciaran S. Hill, Michael D. Jenkinson, Sandhya Trichinopoly Krishna, Stuart Smith, Susruta Manivannan, Andrew J. Martin, Samir Matloob, Soumya Mukherjee, Kevin O’Neill, Puneet Plaha, Jonathan Pollock, Stephen Price, Ola Rominiyi, Bobby Sachdev, Fozia Saeed, Saurabh Sinha, Lewis Thorne, Ismail Ughratdar, Peter Whitfield, Amir Saam Youshani, Helen Bulbeck, Prabhu Arumugam, Richard Houlston, Keyoumars Ashkan

Get full text

Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients by Amanda Bermejo-Gómez, Laura Tarancon-Diez, Beatriz Lazaro-Martin, Begoña Santiago-Garcia, Nuria Gil Villanueva, Roberto Alonso, Mª Ángeles Muñoz-Fernández, Manuela Camino López, Alicia Hernanz-Lobo, María Luisa Navarro Gómez

“…Obtaining satisfactory data on this type of response could potentially challenge the current vaccine guideline recommendations.…”
Get full text

The meaning of ‘quality’ of homecare for older people: a scoping review by Alex Hall, Vanessa Davey, Lisa McGarrigle, Jayne Astbury, Kimberly Lazo Green, Nisar Ahmed, Oleta Williams, Fiona Beyer, Barbara Hanratty, Debora Price

“…Articles were included if they reported views of any stakeholder on quality of care in the context of homecare for older people (aged 65 and above). Data were summarised using a qualitative content analysis approach to identify key dimensions of quality. …”
Get full text

Assessing antibiotic use practices on central Burkina Faso cattle farms and the associated risks to environmental and human health contamination: A pilot study by Djifahamaï Soma, Fatimata Bintou J. Diarra, Isidore Juste O. Bonkoungou, Namwin Siourimè Somda, Evariste Bako, Marguerite Edith M. Nikiema, Souleymane Sore, Natéwindé Sawadogo, Nicolas Barro, Daouda Kassié

“…Materials and Methods: In April 2023, a survey was conducted among 50 cattle farm owners and managers across four peri-urban area of Ouagadougou, Burkina Faso. Data were collected using structured questionnaires through Kobo Toolbox. …”
Get full text

NDVI Estimation Throughout the Whole Growth Period of Multi-Crops Using RGB Images and Deep Learning by Jianliang Wang, Chen Chen, Jiacheng Wang, Zhaosheng Yao, Ying Wang, Yuanyuan Zhao, Yi Sun, Fei Wu, Dongwei Han, Guanshuo Yang, Xinyu Liu, Chengming Sun, Tao Liu

“…This study utilizes field data from five major crops (cotton, rice, maize, rape, and wheat) throughout their whole growth periods. …”
Get full text

Machine learning enhanced metal 3D printing: high throughput optimization and material transfer extensibility by Yuanjie Zhang, Cheng Lin, Yuan Tian, Jianbao Gao, Bo Song, Hao Zhang, Min Wang, Kechen Song, Binghui Deng, Dezhen Xue, Yonggang Yao, Yusheng Shi, Kun Kelvin Fu

“…The high throughput methodologies are mostly on obtaining the printed samples and their structural and physical properties, while ML is used for data analysis by model building for prediction (optimization), and understanding. …”
Get full text

MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis by Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

“…In addition, transcriptomic analysis revealed structural changes specific to excitatory neurons with the A152T mutation. …”
Get full text

Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren’s disease by Shruti Singh Kakan, Sara Abdelhamid, Sara Abdelhamid, Yaping Ju, Yaping Ju, J. Andrew MacKay, J. Andrew MacKay, J. Andrew MacKay, Maria C. Edman, Indu Raman, Chengsong Zhu, Prithvi Raj, Sarah F. Hamm-Alvarez, Sarah F. Hamm-Alvarez

“…Sources of Ig in tears were investigated using scRNA-Seq of the LG (GSE132420). Data were analyzed by R package Limma and Seurat.ResultsAnalysis of immunofluorescence in LG sections from both SjD models showed TLS. …”
Get full text

OptiNeoCare: optimisation of routine care in the management of severe perinatal asphyxia in full-term or near-term newborns – study protocol for analysis of suboptimal care by conf... by Pierre-Yves Ancel, Thierry Debillon, Gilles Cambonie, Geraldine Favrais, Gilles Kayem, Hendy Abdoul, Ayoub Mitha, Isabelle Guellec, Gauthier Loron, Charles Garabedian, Thomas Desplanches, Pierre Delorme, Eric Verspyck, Cyril Huissoud, Marie Delnaud, Blanche Graesslin, Pierre Tourneux, Maliha Badr, Sophie Chapeliere, Marie Brasseur-Daudruy, Max Gonzalez Estevez, Agnes Rigouzzo

“…The quality of care will be assessed based on a structured classification of medical errors (diagnostic, therapeutic, preventive and systemic) by a panel of experts including an obstetrician or midwife and a paediatrician. …”
Get full text

Genetically predicted white matter microstructure mediates the relationship between risk factors and lacunar stroke by Qing Ye, Jie Zhang, Li Zhang, Benyan Luo, Xiangming Ye, Min Wu, Wenshi Wang, Yue Zou, Douglas Neville, Kaisi Ren, Shuchang Zhong, Haiying Xiang

“…We investigated whether genetically predicted white matter (WM) microstructure mediates causal relationships between risk factors and lacunar stroke.Methods Data from genome-wide association studies were used to perform two-sample Mendelian randomisation (MR) analyses. …”
Get full text

Comparative Analysis of Plasma Protein Dynamics in Women with ST-Elevation Myocardial Infarction and Takotsubo Syndrome by Shafaat Hussain, Sandeep Jha, Evelin Berger, Linnea Molander, Valentyna Sevastianova, Zahra Sheybani, Aaron Shekka Espinosa, Ahmed Elmahdy, Amin Al-Awar, Yalda Kakaei, Mana Kalani, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Elmir Omerovic, Björn Redfors

“…Differential expression and functional significance were assessed. Data are accessible on ProteomeXchange, ID PXD051367. …”
Get full text

Coronary inflammation and atherosclerosis by CCTA in young adults (aged 18-45) by Annalisa Filtz, Daniel Lorenzatti, Henry A Dwaah, Carlos Espiche, Santiago F Galgani, Jake T Gilman, Alexandrina Danilov, Andrea Scotti, Piotr J Slomka, Daniel S Berman, Salim S Virani, Mario J Garcia, Khurram Nasir, Leslee J. Shaw, Ron Blankstein, Michael D Shapiro, Damini Dey, Leandro Slipczuk

“…Structured abstract: Background: Peri-coronary adipose tissue attenuation (PCAT), a marker of coronary inflammation, is linked to coronary artery disease (CAD), but data on the role of PCAT in young individuals are limited. …”
Get full text

Assessing the context within academic health institutions toward improving equity-based, community and patient-engaged research by Prajakta Adsul, Shannon Sanchez-Youngman, Elizabeth Dickson, Belkis Jacquez, Alena Kuhlemeier, Michael Muhammad, Katherine J. Briant, Bridgette Hempstead, Jason A. Mendoza, Lisa G. Rosas, Anisha Patel, Patricia Rodriguez Espinosa, Tabia Akintobi, Paige Castro-Reyes, Lori Carter-Edwards, Nina Wallerstein

“…Third, institutional structures created power imbalances and community mistrust which were identified as key barriers to P/CenR. …”
Get full text

Cognitive gains and cortical thickness changes after 12 weeks of resistance training in older adults with low and high risk of mild cognitive impairment: Findings from a randomized... by Simona Kušleikienė, Gal Ziv, Wouter A.J. Vints, Erika Krasinskė, Milda Šarkinaite, Orgesa Qipo, Ivan Bautmans, Uwe Himmelreich, Nerijus Masiulis, Vida J. Česnaitienė, Oron Levin

“…Results: Complete randomized controlled trial data was obtained from 50 individuals (24 with high MCI risk). …”
Get full text

Prospective Evaluation of a Novel Unidirectional Permanent Device for Intraoperative Brachytherapy by Abraham J. Wu, MD, Irini Youssef, MD, Gil’ad N. Cohen, MS, Paul B. Romesser, MD, Neil K. Taunk, MD, Karen Episcopia, MS, Christopher H. Crane, MD, Philip Paty, MD, Julio Garcia-Aguilar, MD, PhD, Martin Weiser, MD, J. Joshua Smith, MD, PhD, Garrett M. Nash, MD, Eugene Cha, MD, Aman Taggar, MD, Zhigang Zhang, PhD, Antonio L. Damato, PhD

“…This facilitates intraoperative placement of permanent brachytherapy seeds in a surgical tumor bed, while minimizing dose to overlying structures. No clinical trial data have yet been published for this device. …”
Get full text

Impact of shared decision-making in Taiwanese patients with atrial fibrillation eligible for novel oral anticoagulant therapy by Yen-Wen Wu, Tsung-Hsien Lin, Yuan-Po Yang, Wei-Tsung Wu, Chung-Ming Tu, Hung-Kain Huang, Chun-Yuan Chu, Chi-Cheng Huang, Szu-Chi Chien, Shih-Jie Jhuo, Ching-Pei Chen

“…Surveys collected data on anxiety about AF, confidence in healthcare professionals, usefulness of the SDM materials, and perception of different NOACs. …”
Get full text

Clinical relevance of loss-of-function mutations of NEMO/IKBKG by Jin Wang, Kexin Shen, Hongxia Lou, Lina Zhou, Yunfei An, Xiaodong Zhao, Yuan Ding

“…Gene mutations and clinical manifestation data were analyzed and reviewed. 144 publications with 564 patients were included in the analysis. …”
Get full text

Farmers’ Perception of Ecosystem Services Provided by Historical Rubber Plantations in Sankuru Province, DR Congo by Joël Mobunda Tiko, Serge Shakanye Ndjadi, Jémima Lydie OBANDZA - AYESSA, Daniel Botshumo Banga, Julien Bwazani Balandi, Charles Mumbere Musavandalo, Jean Pierre Mate Mweru, Baudouin Michel, Olivia Lovanirina Rakotondrasoa, Jean Pierre Meniko To Hulu

“…This study used a mixed methodological approach, integrating semi-structured interviews, focus groups, and statistical analyses including chi-square testing and multiple correspondence factorial analysis (MCAFA) to obtain and analyze the data comprehensively. …”
Get full text

‘I Don't Think There Is a One‐Size‐Fits‐All’: A Qualitative Study Exploring Healthcare Professional and Service Provider Perspectives of Using Innovative Models of Cervical Screeni... by Claire Bavor, Tessa Saunders, Mikayla Wolfe, Megan A. Smith, Nicola Creagh, Deborah Bateson, Angela Kelly‐Hanku, Paula Jops, Marion Saville, Natalie Taylor, Kate Broun, Julia M. L. Brotherton, Claire Nightingale

“…Data were analyzed using template analysis, a form of thematic analysis. …”
Get full text

HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines by Agnieszka Gogler, Agata Małgorzata Wilk, Damian Robert Sojka, Małgorzata Adamiec-Organiściok, Natalia Matysiak, Daria Kania, Klaudia Wiecha, Ewa Małusecka, Alexander Jorge Cortez, Dawid Zamojski, Michał Marczyk, Agnieszka Maria Mazurek, Sylwia Oziębło, Dorota Scieglinska

Get full text