The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells by Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras

“…Finally, we demonstrated that Ca2+ influx by TRPV1 was necessary for recording CAPE-induced cytoplasmic redox changes, a phenomenon captured in real-time in ECs expressing the HyPer biosensor.Our data depict a molecular mechanism behind the antioxidant effect of CAPE in endothelial cells, connecting the activation of TRPV1 ion channels, cytoplasmic calcium increase, and a reduction of disulfide bonds on a redox biosensor. …”
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MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study by Jefree Johari, Robert D. Hontz, Brian L. Pike, Tupur Husain, Norhayati Rusli, Rozainanee Mohd-Zain, Vunjia Tiong, Hai-Yen Lee, Boon-Teong Teoh, Sing-Sin Sam, Chee-Sieng Khor, Shih-Keng Loong, Juraina Abd-Jamil, Siti-Sarah Nor'e, Hasmawati Yahaya, Naim Che-Kamaruddin, Jose A. Garcia-Rivera, Sazaly AbuBakar

“…ELISAs and micro-neutralization assays were performed to detect the presence of MERS-CoV IgG antibodies. Sociodemographic data, symptoms experienced during Hajj, and history of exposure to camels or camel products were recorded using structured pre- and post-Hajj questionnaires. …”
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Traditional uses and importance of Strychnos L. (Loganiaceae): A cross-cultural and spatial variation study in Benin by Donald Djidohokpin, Gbèwonmèdéa Hospice Dassou, Gnimansou Abraham Favi, Octave Mathieu Zountangni, Jéronime Marie-Ange Sènami Ouachinou, Judicael Makponsè, Ghyslain Kpetikou, Gbèkponhami Monique Tossou, Hounnankpon Yédomonhan, Aristide Cossi Adomou

“…Detailed information about uses and homemade herbal remedies regarding the medicinal category was collected. Data were analyzed through the citation frequencies and homemade remedy report (HR) using Excel. …”
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Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy by Jiahui Mai, Jing Duan, Xiaoyu Chen, Liqin Liu, Dachao Liang, Tao Fu, Gang Lu, Wai Yee Chan, Xufeng Luo, Feiqiu Wen, Jianxiang Liao, Zhuo Li, Xinguo Lu

“…We used the optical genome mapping (OGM) technology to detect and analyze uncommon mutations or structural variations (SVs) within the DMD gene, thus contributing to more precise clinical diagnoses. …”
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Audio and linguistic prediction of objective and subjective cognition in older adults: what is the role of different prompts? by Varsha D. Badal, Varsha D. Badal, Caitlyn Tran, Haze Brown, Danielle K. Glorioso, Danielle K. Glorioso, Rebecca Daly, Rebecca Daly, Anthony J. A. Molina, Anthony J. A. Molina, Alison A. Moore, Alison A. Moore, Erhan Bilal, Ellen E. Lee, Ellen E. Lee, Ellen E. Lee, Colin A. Depp, Colin A. Depp, Colin A. Depp

“…BackgroundPsycho-linguistic and audio data derived from speech may be useful in screening and monitoring cognitive aging. …”
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The Class III Peroxidase Gene Family in <i>Populus simonii</i>: Genome-Wide Identification, Classification, Gene Expression and Functional Analysis by Lu Han, Yishuang Ren, Xinru Bi, Guowei Yao, Jinwang Zhang, Hongtao Yuan, Xiaoyu Xie, Junbo Chen, Yunchang Zhang, Sitong Du, Wanying Chen, Kewei Cai, Xiyang Zhao

“…Transcriptome data showed that the expression of <i>PsPOD</i> genes varies significantly across different tissues and organs and under various stress conditions, suggesting their involvement in both developmental processes and abiotic stress responses. …”
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Assessment of usage, reuse and disposal of thermoplastic masks among radiotherapy technologists in India: A nationwide perspective by M. Nagesh, Rohit Vadgaonkar, K.K. Sreelakshmi, Raghavendra Hajare, Pritam Parab, Subhabrat Dash, Ramesh Reddy, Vaishali Shende, Ankita Nawar, Rahul Biswas, Sandeep Ratna Bula, Shubham Gagare, Darshani Belekar, Raviteja Miriyala, Umesh Mahantshetty

“…Questionnaire encompassed data pertaining to demographics, existing patient load, daily utilisation and reuse practice of TMs, preferred method of disposal and awareness of RTTs regarding environmental consequences associated with TM disposal. …”
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CTV-MIND: A cortical thickness-volume integrated individualized morphological network model to explore disease progression in temporal lobe epilepsy by Xinyan Liu, Jiaqi Han, Xiating Zhang, Boxuan Wei, Lu Xu, Qilin Zhou, Yuping Wang, Yicong Lin, Jicong Zhang

“…This study aimed to investigate progressive changes in TLE by constructing a novel individualized morphological brain network based on T1-weighted structural magnetic resonance imaging (MRI). MRI data were collected from 34 postoperative seizure-free TLE patients and 28 age- and sex-matched healthy controls (HC), with patients divided into LONG-TERM and SHORT-TERM groups. …”
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Hydrogen Column Density Variability in a Sample of Local Compton-thin AGN II by A. Pizzetti, N. Torres-Albà, S. Marchesi, J. Buchner, I. Cox, X. Zhao, S. Neal, D. Sengupta, R. Silver, M. Ajello

“…Among these, 30% exhibit recorded 22 GHz water megamaser emission, suggesting a potential shared nature between the two structures.…”
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Prevalence and risk factors of Helicobacter pylori infection in urban children aged 6–13 years in Fuzhou, China: a cross-sectional study in a high gastric cancer incidence region by Youtao Chen, Youtao Chen, Youtao Chen, Xiaoting Pan, Xiaoting Pan, Xiaoting Pan, Yanyan Wang, Yanyan Wang, Longzhen Lin, Xiaoyan Chen, Xiaoyan Chen, Yan Chen, Yan Chen, Hong Ye, Hong Ye, Hong Ye

“…BackgroundThe burden of Helicobacter pylori infection remains a global public health concern, particularly due to its lifelong risk of gastric cancer starting from childhood. Comprehensive data on the prevalence of H. pylori infection and associated risk factors among children are limited. …”
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Examining the effects of school–vacation transitions on depression and anxiety in adolescents: network analysis by Yumeng Ju, Yumeng Yang, Rui Yuan, Yafei Chen, Junwu Liu, Wenwen Ou, Yunjing Li, Siqi Yang, Yimei Lu, Liang Li, Mei Huang, Mohan Ma, Guanyi Lv, Xiaotian Zhao, Yaqi Qing, Jin Liu, Yan Zhang

“…Network analysis was used to explore the symptom network structures of depression and anxiety during school and vacation. …”
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Imputation models and error analysis for phase contrast MR cerebral blood flow measurements in heterogeneous pediatric and adult populations by Eamon K. Doyle, Eamon K. Doyle, Isabel Torres, Isabel Torres, Joseph Liu, Abhishek Karnwal, Sudarshan Ranganathan, Sudarshan Ranganathan, Bradley J. De Souza, Payal Shah, Bradley S. Peterson, John C. Wood, John C. Wood, Matthew Thomas Borzage, Matthew Thomas Borzage, Matthew Thomas Borzage, Matthew Thomas Borzage

“…Subsequently, we developed mathematical models to predict the missing data. Our predictive models performed well; across the human lifespan when at least one ICA measurement was available, our normalized root mean squared error values were low (&lt;0.137), our R-squared values were high (&gt;0.91), and we observed high intra-class correlation coefficients (&gt;0.951). …”
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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

“…Objective We aimed to compare the incidence of severe infections between mycophenolate mofetil (MMF) and other immunosuppressants in patients with systemic lupus erythematosus (SLE) on maintenance therapy using data from the Lupus Registry of Nationwide Institutions in Japan.Methods This study employed a prospective cohort design, including patients with SLE undergoing maintenance therapy. …”
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Bringing a Systems Approach to Living Donor Kidney Transplantation by Anna Horton, Katya Loban, Peter Nugus, Marie-Chantal Fortin, Lakshman Gunaratnam, Greg Knoll, Istvan Mucsi, Prosanto Chaudhury, David Landsberg, Michel R. Pâquet, Marcelo Cantarovich, Shaifali Sandal

“…Findings may be used to guide structured organizational change toward increasing LDKT and mitigating the global burden of kidney failure.…”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Measurement invariance of the TAPAS was tested to ensure that the combining of data from Hong Kong and Taiwan participants was appropriate for further analysis. …”
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Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia by Melanie A. Matyi, Hamsanandini Radhakrishnan, Christopher A. Olm, Jeffrey S. Phillips, Philip A. Cook, Emma Rhodes, James C. Gee, David J. Irwin, Corey T. McMillan, Lauren Massimo

“…Methods: In a sample of 90 patients with bvFTD and 71 age-matched CNC with diffusion MRI data we generated probabilistic tractography maps and calculated system segregation, a metric that compares within-network to between-network connectivity, to reflect the extent to which brain networks were differentiated. …”
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Balancing accuracy and user satisfaction: the role of prompt engineering in AI-driven healthcare solutions by Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Peijin Zeng, Peijin Zeng, Peijin Zeng, Xinyue Li, Kelvin Kam-Lung Chong, Guanghui Hou, Xiaoxiao Fang, Yang Yu, Xiangrong Yu, Junbin Fang, Yi Pan

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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Results In this study, we profiled 71,798 cells from domestic pig and wild boar cerebral cortex and cerebellum, identifying nine cell types, and integrated single-cell RNA sequencing data to explore cell type-specific regulatory landscapes and oligodendrocyte developmental trajectory. …”
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White matter integrity and functional connectivity in adolescents with a parental history of substance use disorder by Xiaofu He, Diana V. Rodriguez-Moreno, Yael M. Cycowicz, Keely Cheslack-Postava, Huilan Tang, Zhishun Wang, Lawrence V. Amsel, Megan Ryan, Lupo Geronazzo-Alman, George J. Musa, Adam Bisaga, Christina W. Hoven

“…We acquired diffusion tensor-imaging (DTI) and resting state fMRI data across the whole brain. Structural connectivity was examined by measuring fractional anisotropy (FA) using DTI, to indicate integrity of the white matter tracts. …”
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The microbiologist's guide to metaproteomics by Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative

“…Topics covered include experimental design, sample preparation, mass spectrometry techniques, data analysis strategies, and statistical approaches.…”
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