Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicryResearch in context by Xin Ma, Jian Zhang, Qianling Jiang, Yong-Xin Li, Guan Yang

“…Of note, half of these analogs could bind to MHC II and interact with TCR through structural modeling of the interaction using fine-tuned AlphaFold. …”
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Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure by Zhenglong Guo, Yunfei Liu, Zhiming Zhou, Jianchao Chen, Lin Guo, Keke Liang, Yibin Hao, Bingtao Hao, Bin Yang, Shixiu Liao

“…Correlation analyses between RNA-seq and WGBS data were executed by integrating differentially expressed genes (DEGs) with genes associated with differentially methylated regions (DMRs) located in the promoter regions. …”
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Unravelling typology of family life when a parent has heart disease: A qualitative study of families with adolescents by Matilda Holmbom, Hanna Grundström, Frida Andréasson, Camilla Rotvig, Hege Andersen, Camilla Bernild, Tone Merete Norekvål, Selina Kikkenborg Berg, Anna Strömberg

“…Inclusion criteria were families with a parent living with any type of heart disease, within six months and up to five years since diagnosis and having one or more adolescents living at home. Methods: Data was collected through semi-structured individual interviews. …”
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A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein by Juan José Valenzuela-Fuenzalida, Benjamín Rodríguez-Osorio, Cristian Salgado-Torres, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandro Bruna-Mejías, Roberto Avila-Sepulveda, Álvaro Becerra-Farfán, Macarena Rodríguez-Luengo, Juan Sanchis-Gimeno, Guinevere Granite, Héctor Gutiérrez-Espinoza

“…Tree authors independently performed the search, study selection and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies. …”
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Spanish Nurses’ Knowledge and Perceptions of Climate Change: A Qualitative Study by Antonio Miguel Caraballo-Betancort, Irene Marcilla-Toribio, Blanca Notario-Pacheco, Maria Leopolda Moratalla-Cebrian, Ana Perez-Moreno, Alba del Hoyo-Herraiz, Raquel Poyatos-Leon, Maria Martinez-Andres

“…Purposive and snowball sampling strategies were used to recruit nurses from emergency services, geriatrics, cardiology, respiratory medicine and primary care in nine different regions of Spain. Semi-structured online interviews were conducted. Data analysis was carried out by three researchers via a three-stage inductive thematic analysis approach. …”
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Ophthalmologists’ and patients’ perspectives on treatments for diabetic retinopathy and maculopathy in Vietnam: a descriptive qualitative study by Tunde Peto, Nathan Congdon, Lynne Lohfeld, Hoang Tran, Katie Curran, Van Thu Nguyen, Tung Thanh Hoang, Hue Thi Nguyen, Quan Nhu Nguyen, Catherine Dardis, Hoang Huy Tran, Anh Tuan Vu, Mai Quoc Tung

“…Thematic analysis was used to analyse the data.Results In total, 10/24 (41.7%) ophthalmologists were female, and their median age was 41 years (range 29–69 years). …”
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Strengthening the delivery of integrated care for individuals experiencing serious mental illness within mental health settings: a qualitative description of health provider perspe... by Munazzah Ambreen, Christopher Canning, Brian Lo, Sri Mahavir Agarwal, Amer M. Burhan, David Castle, M. Elisabeth Del Giudice, Barna Konkolÿ-Thege, Louis Liu, Osnat C. Melamed, Frank Sirotich, Sanjeev Sockalingam, Gillian Strudwick, Tania Tajirian, Philip G. Tibbo, Mary Rose van Kesteren, Caroline Walker, Vicky Stergiopoulos

“…Methods This qualitative descriptive study involved conducting individual semi-structured interviews with 13 health administrators and four focus groups with 15 clinicians between July 2023 and April 2024. …”
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Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project by Linda Sharp, Sarah Bailey, Colin Rees, Willie Hamilton, Dawn Craig, Joe West, David Humes, Gary Abel, James Turvill, Brian Nicholson, Chloe Thomas, Jim Chilcott, Colin Crooks, Olena Mandrik, John Whelpton

“…We assessed the cost-effectiveness of COLOFIT compared with FIT and investigated optimal risk thresholds.Methods An individual patient-level simulation model was developed, with synthetic populations constructed from data used to validate COLOFIT. Referral criteria based on different FIT scores and COLOFIT-assessed risk thresholds were modelled using probabilistic and scenario analyses. …”
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A high‐affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain by Nikolaj R Christensen, Marta De Luca, Michael B Lever, Mette Richner, Astrid B Hansen, Gith Noes‐Holt, Kathrine L Jensen, Mette Rathje, Dennis Bo Jensen, Simon Erlendsson, Christian RO Bartling, Ina Ammendrup‐Johnsen, Sofie E Pedersen, Michèle Schönauer, Klaus B Nissen, Søren R Midtgaard, Kaare Teilum, Lise Arleth, Andreas T Sørensen, Anders Bach, Kristian Strømgaard, Claire F Meehan, Christian B Vægter, Ulrik Gether, Kenneth L Madsen

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Diagnostic yield of 1000 trio analyses with exome and genome sequencing in a clinical setting by Helena Malmgren, Helena Malmgren, Malin Kvarnung, Malin Kvarnung, Peter Gustafsson, Peter Gustafsson, Britt-Marie Anderlid, Britt-Marie Anderlid, Cecilia Arthur, Cecilia Arthur, Jonas Carlsten, Jonas Carlsten, Karl De Geer, Karl De Geer, Emma Ehn, Emma Ehn, Giedre Grigelioniené, Giedre Grigelioniené, Anna Hammarsjö, Anna Hammarsjö, Hafdis T. Helgadottir, Hafdis T. Helgadottir, Maritta Hellström-Pigg, Maritta Hellström-Pigg, Erik Iwarsson, Erik Iwarsson, Ekaterina Kuchinskaya, Ekaterina Kuchinskaya, Hillevi Lindelöf, Hillevi Lindelöf, Maria Mannila, Maria Mannila, Daniel Nilsson, Daniel Nilsson, Maria Pettersson, Maria Pettersson, Eva Rudd, Eva Rudd, Ellika Sahlin, Ellika Sahlin, Bianca Tesi, Bianca Tesi, Emma Tham, Emma Tham, Håkan Thonberg, Håkan Thonberg, Eini Westenius, Eini Westenius, Johanna Winberg, Johanna Winberg, Max Winerdal, Max Winerdal, Magnus Nordenskjöld, Magnus Nordenskjöld, Maria Johansson-Soller, Maria Johansson-Soller, Valtteri Wirta, Valtteri Wirta, Ann Nordgren, Ann Nordgren, Anna Lindstrand, Anna Lindstrand, Kristina Lagerstedt-Robinson, Kristina Lagerstedt-Robinson

“…Our current protocol for trio analysis is based on genome sequencing data, which allows for simultaneous detection of single nucleotide variants, insertion/deletions, structural variants, expanded short tandem repeats, as well as a copy number analysis corresponding to an array-CGH, and analysis regarding SMN1 gene copies.…”
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Transdiagnostic Symptom Domains Have Distinct Patterns of Association With Head Motion During Multimodal Imaging in Children by Kavari Hercules, Zhiyuan Liu, Eleni Christofilea, Jia Wei, Gladys Venegas, Olivia Ciocca, Alice Dyer, Goeun Lee, Sasha Santini-Bishop, Heather Shappell, Dylan G. Gee, Denis G. Sukhodolsky, Karim Ibrahim

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Stigma measurement in health: a systematic reviewResearch in context by Sara Malone, Lara Counts, Luke Zabotka, Anneliese Williams, Nele Loecher, Kayla Wynja, Gemma Bryan, Robin Tanner, Ana Cáceres-Serrano, Gia Ferrara, Lucia Fuentes, Tharwa Bilbeisi, Marissa Maheu, Benjamin K. Oelkers, Muna Ogwo, Lauren Yaeger, Asya Agulnik, Dylan Graetz, Shayla Lawrence, Jocelyn Rivera, Farris Abutineh, Doris Maldonado

“…Databases were searched for stigma measurement in health through July 2024. 8123 citations were screened. Data on definitions, measurement, psychometrics, and interventions were extracted. …”
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Evaluation and implementation of multidisciplinary, standardized, guideline-based long-term follow-up care for adult survivors of childhood cancer in Germany: protocol of a prospec... by C. Cytera, K. Baust, A. Borgmann-Staudt, G. Calaminus, K. Egger-Heidrich, J. Faber, D. Grabow, T. Halbsguth, A. Kock-Schopenhauer, I. R. König, S. Michaelis, A. Neumann, A. Puzik, S. Schuster, F. Wolters, C. Arendt, M. Sleimann, T. Langer, J. Gebauer

“…The LE-Na study aims to: 1. implement and/or improve LTFU care structures for adult CCS in Germany, 2. inform former patients about late effects and LTFU care centers, 3. create a basis for future research by building up a central database, consent management and infrastructure, 4. establish a clinical LTFU cohort of adult CCS in Germany, 5. evaluate the implementation of the LFTU care, 6. enable the expansion of LTFU care structures nationwide, 7. integrate the developed LTFU care structures into the standard health care system. …”
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Flexible Glass Hybridized Colloidal Quantum Dots for Gb/s Visible Light Communications by Caroline Foucher, Mohamed Islim Sufyan, Benoit Jack Eloi Guilhabert, Stefan Videv, Sujan Rajbhandari, Ariel Gomez Diaz, Hyunchae Chun, Dimali A. Vithanage, Graham A. Turnbull, Ifor D. W. Samuel, Grahame Faulkner, Dominic C. O'Brien, Harald Haas, Nicolas Laurand, Martin D. Dawson

“…These structures are less than 70 μm in total thickness and are directly placed in contact with the polished sapphire substrate of 450-nm-emitting μLEDs. …”
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Identifying barriers and facilitators for health risk behaviours among people with severe mental illness in Bangladesh and Pakistan: a qualitative study by Badur Un Nisa, Imogen Featherstone, Gerardo A. Zavala, Humaira Bibi, Md Badruddin Saify, Mahmudul Hasan, Faiza Aslam, Asad Tamizuddin Nizami, Rumana Haque, Najma Siddiqi, Richard I.G. Holt, Hannah Maria Jennings

“…Data were analysed thematically, informed by the socio-ecological framework. …”
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Temperature and excipient mediated modulation of monoclonal antibody interactions revealed by kD, rheology, and Raman spectroscopy by Olivia Noelle Eskens, Sabitoj Singh Virk, Akashdeep Singh Virk, Deepika Venkataramani, Maureen Crames, Maria Calderon Vaca, Matthew Matusewicz, Connor Smith, Joshin George, Collin Taylor, Michael S. Marlow, Samiul Amin

“…Raman spectral analysis of Amide I/III regions confirmed structural invariance under thermal and shear stress, attributing viscosity modulation to colloidal rather than conformational perturbations. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…Despite studies conducted, there are no unambiguous data showing how IMQ affects the condition of tumor blood vessels. …”
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Evaluating acceptability and experiences of pregnant women at high risk of developing gestational diabetes who take part in antenatal intervention trials: a qualitative systematic... by Gözde Sultan Çakır, Manar Abduljalil Bakhsh, Ola F. Quotah, Olivia Righton, Catherine V. George, Lucilla Poston, Sara L. White, Angela C. Flynn, Zoë Bell

“…All were pilot RCTs using semi-structured interviews in high-income countries (UK n = 3, USA n = 1). …”
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EXPERIMENTAL EVALUATION OF LONG-TERM ADVERSE SIDE EFFECTS OF CYTOSTATIC DRUGS ON FEMALE REPRODUCTIVE FUNCTION AND PHARMACOLOGICAL WAYS TO REDUCE THEM by T. G. Borovskaya, V. E. Goldberg, M. E. Poluektova, A. V. Vychuzhanina, Yu. A. Shchemerovа, V. A. Grigoreva, A. A. Ligacheva, E. A. Bokhan

“…Statistical processing of obtained experimental data was performed using Mann-Whitney U-test and Fisher angular transformation.Results. …”
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Development of the 10-question household foodwork interactional assessment questionnaire (FIA-Q10) by Leah E. Cahill, Sharon I. Kirkpatrick, Catherine L. Mah, Jennifer LP. Protudjer, Cynthia Kendell, Mary E. Jung, Helen Wong, Ellen T. Crumley, Meghan Day, Karen T. Y. Tang, Yan Huang, Jyoti Sihag, Laura Brady, Karthik K Tennankore, Navdeep Tangri, Rebecca C. Mollard, Dylan MacKay

“…An optional accompanying module was developed to collect self-identified demographic data to provide context for understanding how social-structural positionality factors may interact to influence foodwork. …”
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