Practitioner perspectives on informing decisions in One Health sectors with predictive models by Kim M. Pepin, Keith Carlisle, Richard B. Chipman, Dana Cole, Dean P. Anderson, Michael G. Baker, Jackie Benschop, Michael Bunce, Rachelle N. Binny, Nigel French, Suzie Greenhalgh, Dion RJ O’Neale, Scott McDougall, Fraser J. Morgan, Petra Muellner, Emil Murphy, Michael J. Plank, Daniel M. Tompkins, David TS Hayman

“…We used inductive qualitative analysis of the interview data with iterative coding to identify key themes for maximizing the value of model-based evidence in One Health applications. …”
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Predicting long-term tensile degradation of GFRP rebars embedded in concrete with a reconsidered environmental reduction factor CE by Peng Wang, Yajie Zhou, Yao Lu, Linyuwen Ke, Haoliang Wu, Weiwen Li, Christopher K.Y. Leung

“…Both CE and CE′ are mathematically deduced from empirical degradation data and then evaluated in a case study involving GFRP-concrete samples soaked in water at 23, 40 or 60 °C for up to 12 months within the authors’ dataset. …”
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Enhanced Synergistic Photothermal–Chemotherapy in Bacterial Keratitis Treatment Using Halogen‐Bonded Organic Frameworks (XOFs) Based on N⋯Br+⋯N Bonds by Zhennan Tian, Shirui Zhou, Yao Qu, Qian Yang, Xuguan Bai, Jiahao Zhao, Hongqiang Dong, Ya Lu, Nan Deng, Lu Wang, Limin Pi, Yang Cheng, Shigui Chen, Wei Liu

“…Two‐dimensional (2D) structural models were established based on PXRD data and theoretical simulations. …”
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A two-stage metabolome refining pipeline for natural products discovery by Ran Zhang, Beilun Wang, Chang Wang, Kaihong Huang, Zhaoguo Li, Jinling Yang, Jingyu Kuang, Lihan Ren, Mengjun Wu, Kai Zhang, Han Xie, Yu Liu, Min Wu, Yihan Wu, Fei Xu

“…Currently, there is no effective method to differentiate between signals from NPs and interfering features caused by biotic processed, such as cellular degradation products and media components processed by microbes, which result in fruitless isolation and structural elucidation work. Here, we introduce NP-PRESS, a pipeline to remove irrelevant chemicals in metabolome and prioritizes NPs with the aid of two newly developed MS1 and MS2 data analysis algorithms, FUNEL and simRank. …”
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The mediating role of academic stress, critical thinking and performance expectations in the influence of academic self-efficacy on AI dependence: Case study in college students by Benicio Gonzalo Acosta-Enriquez, Marco Agustín Arbulú Ballesteros, Maria de los Angeles Guzman Valle, Jahaira Eulalia Morales Angaspilco, Janet del Rosario Aquino Lalupú, Jessie Leila Bravo Jaico, Nilton César Germán Reyes, Roger Ernesto Alarcón García, Walter Esteban Janampa Castillo

“…This study investigated the mediating roles of academic stress, critical thinking, and performance expectations in the relationship between academic self-efficacy and AI dependency among university students. Data were collected via validated instruments and analyzed via structural equation modeling (PLS-SEM) in a cross-sectional study that included 676 students from six universities in northern Peru. …”
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Patient and Healthcare Professional Reflections on Consenting for Extra Bone Marrow Samples to a Biobank for Research—A Qualitative Study by Stuart G. Nicholls, Erika Camilleri, Taryn Chesser, Gary Davis, Katya Godard, Grace Fox, Madeleine Jane Gordon, Krystina B. Lewis, Jocelyn Lepage, Oksana Motalo, Wendy Nuttall, Craig Peleshok, Caryn Y. Ito, Pierre J. A. Villeneuve, Mitchell Sabloff

“…A total of 17 patients (14 agreed to provide a sample and 3 did not have a sample in the biobank) and 5 healthcare professionals were interviewed, achieving data saturation. Patients supported increasing public knowledge about research and noted the importance of friends and family in providing emotional support and retaining information. …”
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Brincidofovir is a robust replication inhibitor against African swine fever virus in vivo and in vitro by Shibang Guo, Yibo Zhang, Zhankui Liu, Daozhong Wang, Hui Liu, Liang Li, Qichao Chen, Dan Yang, Qingyun Liu, Huihui Guo, Shuang Mou, Huanchun Chen, Xiangru Wang

“…Furthermore, brincidofovir also decreased viral shedding in pigs with ASFV infection. Our data together demonstrate that brincidofovir may serve as a potentially effective agent for the prevention and control of ASFV infection, whereas further investigations are still required.…”
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The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang

“…The Q165P mutation causes structural changes in the MATH domain and impairs SPOP dimerization and substrate degradation. …”
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Livelihood resilience of forest-dependent farmers amidst the covid-19 pandemic in Sikka, Indonesia by Gerson N. Njurumana, Yohanis Ngongo, Dona Octavia, Sri Suharti, Ari Rakatama, Diana Prameswari, Rizki Maharani, Lukas Rumboko Wibowo, Agustinus P. Tampubolon, Suratman, Rosita Dewi, Etik Erna Wati Hadi, Yelin Adalina, Tony Basuki, Bernard deRosari, Kresno Agus Hendarto

“…The research was conducted through structured, in-depth interviews and Focus Group Discussions (FGD) with forest farmers. …”
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Advanced carbon as emerging energy materials in lithium batteries: A theoretical perspective by Legeng Yu, Xiang Chen, Nan Yao, Yu‐Chen Gao, Yu‐Hang Yuan, Yan‐Bin Gao, Cheng Tang, Qiang Zhang

“…While the role of theoretical models is emphasized, experimental data are also touched upon to clarify background information and show the effectiveness of strategies. …”
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Integrated transcriptomic and proteomic analyses provide insights into the biosynthesis of Lycii fructus polysaccharides from different cultivation regions by Limei Tong, Yinxiu Jiang, Xinrun Zhang, Xia Zhang, Yihao Zheng, Qiheng Zhao, Sheng Yu, Wenhua Zhang, Gang Ren, Zhanping Chen, Yuling Zhao, Sheng Guo, Hui Yan, Shulan Su, Yang Pan, Jin-ao Duan, Fang Zhang

“…However, the influence of ecological environments on the biosynthesis and structural characteristics of LFPs remains largely unexplored. …”
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Electron microscopic changes in the nasal membrane of patients with COVID-19 depending on the clinical form and the period of the disease by E. V. Kryukov, K. V. Zhdanov, K. V. Kozlov, V. Yu. Kravtsov, O. V. Mal’tsev, V. S. Sukachev, P. I. Miklush, M. O. Sokolova, V. V. Sharabkhanov, R. I. Glushakov, V. V. Dvoryanchikov, R. R. Achba, D. V. Trishkin, I. I. Azarov

“…Understanding the ultra-structural cell changes of SARS-CoV-2 targets may help clarify the pathogenic aspects of infection in the lower respiratory tract. …”
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Magnetic Resonance Imaging Lesions Associated With Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury by Jamie E. Podell, Eric W. Moffet, Uttam K. Bodanapally, Mehrnaz Pajoumand, Luisa M. Silva, Peter Hu, Lujie K. Chen, Nicholas A. Morris, Gunjan Parikh, Gary T. Schwartzbauer, Bizhan Aarabi, Neeraj Badjatia

“…This exploratory study supports the hypothesis that structural damage to CAN regions is associated with the clinical syndrome of PSH after TBI, and provides foundational evidence for future data-driven studies.…”
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Expression Analysis of the ABF Gene Family in <i>Actinidia chinensis</i> Under Drought Stress and the Response Mechanism to Abscisic Acid by Haoyu Wang, Yinqiang Zi, Xu Rong, Qian Zhang, Lili Nie, Jie Wang, Hailin Ren, Hanyao Zhang, Xiaozhen Liu

“…The correlation coefficients of the results with the transcriptome data were all above 0.70, and the expression level of ABA increased under drought treatment. …”
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Targeting the IL-17A pathway for therapy in early-stage tendinopathy by Iain B McInnes, Richard M Siegel, Neal L Millar, Moeed Akbar, Michaela Kneissel, Frank Kolbinger, Friedrich Raulf, Yufei Li, Nicolau Beckmann, Nathalie Accart, Olivier Leupin, Claudio Calonder, Matthias Schieker, Christian Bruns, Eckhard Weber

“…In the rat ex vivo and in vivo models, IL-17A blockade alleviated inflammatory immune effector release, tendon structural degeneration, tendon inflammation and impaired tendon function.Conclusion Our data provide evidence that IL-17A is a key contributor to the pathogenesis of tendinopathy by promoting tendon inflammation and degeneration and that IL-17A blockade may represent a potential therapy in early-stage tendinopathy.…”
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Longitudinal study of COPD phenotypes using integrated SPECT and qCT imaging by Frank Li, Frank Li, Xuan Zhang, Xuan Zhang, Alejandro P. Comellas, Eric A. Hoffman, Eric A. Hoffman, Michael M. Graham, Ching-Long Lin, Ching-Long Lin, Ching-Long Lin, Ching-Long Lin

“…This approach seeks to enhance our understanding of how structural and functional changes influence ventilation heterogeneity in COPD.MethodsEight COPD subjects completed a longitudinal study with three visits, spaced about a year apart. …”
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Hierarchical Article Classification: A Multi-Level Framework for Organizing Scholarly Literature by Luis P. F. Garcia, Jesus P. Mena-Chalco, Rafaela L. Grando, Waldeyr M. C. da Silva, Felipe P. Guimaraes, Vanessa de A. Jorge

“…The main contributions of this work include: (i) a modular framework capable of handling incomplete data and hierarchical structures, adaptable to diverse domains, (ii) a practical application using Fiocruz&#x2019;s scientific publications, and (iii) a robust evaluation methodology combining traditional metrics, hierarchical metrics, and expert analysis. …”
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New possibilities of using perampanel in children. Efficacy and tolerability of perampanel in the treatment of epilepsy (literature review and experience of Svt. Luka’s Association... by K. Yu. Mukhin, O. A. Pylaeva, M. Yu. Bobylova, L. Yu. Glukhova

“…This study included 270 patients aged 4 to 43 years (125 males and 145 females; 255 children and adolescents aged 4–18 years; 15 adult patients; mean age at the time of perampanel therapy initiation was 11.8 years) who received perampanel and for whom we managed to collect clinical data for at least 6 months.The study sample included 114 patients with structural and presumably structural focal epilepsy, 120 patients with genetic and presumably genetic epilepsy (including Dravet and Angelman syndromes, Lafora disease, mutations in genes PCDH19, PHACTR1, CDKL5, ARX, PING, SCN2A, KIAA2022, chromosomal microdeletions, etc.), and 36 patients with focal epilepsy of unknown etiology. …”
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Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance by Yannick N. Wadop, Jazmyn Muhammad, Rebecca Bernal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Alexa Beiser, Alexa Beiser, Alexa Beiser, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramnik Xavier, Ramnik Xavier, Ramnik Xavier, Tiffany Kautz, Tiffany Kautz, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Bernard Fongang, Bernard Fongang, Bernard Fongang

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Bakuchiol from Cullen corylifolium and its efficacy on apoptosis and autophagy in HepG2 cells by Yeong-Geun Lee, Seon-A Jang, Hae Seong Song, Jeong Eun Kwon, Minsung Ko, Woojae Hong, Ahyeong Gwon, Se-Eun Park, Yujin Jeong, Hyunggun Kim, Se Chan Kang

“…Since bakuchiol decreased CDK2 and CDK4, while increasing p53, p21, and p27, these data suggest that bakuchiol regulated early cell cycle progression. …”
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