The first generic tirzepatide GP30931: physicochemical and biological similarity to the reference drug by I. A. Lugovik, A. V. Babina, S. S. Arutyunyan, D. О. Ermolaeva, V. B. Saparova, T. N. Kobeleva, P. G. Zaikin, A. D. Mikushina, A. S. Bukatin, I. E. Eliseev, B. Ts. Zajchik, Y. S. Keruchenko, I. S. Ohrimenko, E. V. Bocharov, A. Kh. Taldaev, V. A. Lushpa, I. E. Makarenko, R. V. Drai

“…NMR spectra, CD and CF profiles, and DLS were completely consistent, which allows us to conclude that the secondary and tertiary structures of the preparations are structurally identical. …”
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Genetic assessment of Saccharina germplasm using SNP markers: Facilitating core collection establishment and fingerprinting identification by Zihan Gai, Shuxiu Chen, Shan Sai, Liping Liu, Yuting Zhai, Rui Qian, Ruina Wu, Juping Zhao, Liqin Wang, Yan Li, Yanling Liu, Weiwei Wang, Xiaojie Li, Linan Zhang

“…Despite extensive efforts to collect and preserve its germplasms, the absence of genetic data and reliable molecular markers has obstructed their effective utilization, thereby limiting genetic improvement of S. japonica. …”
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Two Distinctly Different Characteristics of Flare-driven Coronal Rain Revealed from High-resolution Spectroscopic Imaging Observations with FISS/GST by Donguk Song, Eun-Kyung Lim, Jongchul Chae, Maria S. Madjarska, Masahito Kubo, Hannah Kwak, Juhyung Kang, Ryohtaroh T. Ishikawa, Kyoung-Sun Lee

“…We estimate the spatial scale of the fine structure of the coronal rain and the footpoint brightening. …”
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Characteristics of atmospheric variables over the southern coast of West Java in the presence of Australian Monsoon and MRG waves by Didi Satiadi, Trismidianto, Anis Purwaningsih, Dita Fatria Andarini, Risyanto, Teguh Harjana, Ibnu Fathrio, Alfan Sukmana Praja, Noersomadi, Fadli Nauval, Elfira Saufina, Ina Juaeni, Adi Witono, Aisya Nafiisyanti, Wendi Harjupa, Eddy Hermawan, Robi Muharsyah, Danang Eko Nuryanto

“…The Global Navigation Satellite System - Radio Occultation (GNSS-RO) and the latest ECMWF climate reanalysis (ERA5) data were used to identify the MRG waves features using Hovmöller, space-time spectral, and wavelet analyses. …”
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JWST/NIRCam Paβ Narrowband Imaging Reveals Ordinary Dust Extinction for Hα Emitters within the Spiderweb Protocluster at z = 2.16 by Jose Manuel Pérez-Martínez, Helmut Dannerbauer, Yusei Koyama, Pablo G. Pérez-González, Rhythm Shimakawa, Tadayuki Kodama, Yuheng Zhang, Kazuki Daikuhara, Chiara D’Eugenio, Abdurrahman Naufal

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Factors Influencing Measles Vaccine Compliance: A Descriptive-correlational Study in Barangay C, Northern Mindanao by Rhy Kenji Enguio, Zenju Espinosa, Ashley Jenn Fallarna, Ferdinand Gabriel Galarrita, Justine Jean Guillermo, Jasimah Gutoc, Rhea Mae Janolino, Aleks Jimenez, Kayle Mae Labasano, Jade Godwin Lagua, Ariel Lacdo-O, Edmund Zheen Regor Moreno, Paolo Araune, Ivy Go

“…Materials and Methods: This study utilized a non-experimental quantitative descriptive design to examine factors influencing measles vaccination compliance among residents of barangay C. The study data were collected using a structured survey questionnaire that served as the instrument designed to measure compliance across psychosocial factors and behavioral-specific cognitions. …”
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Integrated assessment of antimicrobial stewardship in carbapenem resistant Klebsiella pneumoniae prevalent hospitals in China: a multidisciplinary surveillance network-based survey by Haishaerjiang Wushouer, Weibin Li, Junxuan Yu, Lin Hu, Xiaodong Guan, Xiaolin Liu, Anhua Wu, Xiaoqiang Yang, Minggui Wang, Yingchun Xu, Yanping Luo, Xun Huang, Luwen Shi

“…Five key areas were identified for improving multidisciplinary AMS: organizational structure, staffing and training, drug formulary and prescription management, laboratory testing and quality control, and clinical sampling and data reporting. …”
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Multifractal Analysis and Experimental Evaluation of MCM-48 Mesoporous Silica as a Drug Delivery System for Metformin Hydrochloride by Mousa Sha’at, Maria Ignat, Liviu Sacarescu, Adrian Florin Spac, Alexandra Barsan (Bujor), Vlad Ghizdovat, Emanuel Nazaretian, Catalin Dumitras, Maricel Agop, Cristina Marcela Rusu, Lacramioara Ochiuz

“…The multifractal dynamics-based theoretical release curves closely matched the experimental data. <b>Conclusions</b>: MCM-48 mesoporous silica effectively enhanced metformin delivery, offering a controlled release profile well-suited for type 2 diabetes management. …”
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Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future by Emmama Jamil, Emmama Jamil, Zikria Saleem, Brian Godman, Brian Godman, Brian Godman, Matti Ullah, Afreenish Amir, Abdul Haseeb, Johanna C. Meyer, Johanna C. Meyer, Muhammad Usman Qamar, Safa S. Almarzoky Abuhussain

“…The findings highlighted significant disparities in the development, adaptation, and implementation of guidelines across different WHO regions, confirming the previously noted lack of standardization and comprehensiveness in LMICs.ConclusionSignificant disparities exist in the availability, structure, and methodological rigor of antibiotic prescribing guidelines across countries with different income levels. …”
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Chronic unilateral vestibular hypofunction: a qualitative study exploring the full spectrum of symptoms and impacts through the ICF framework by Mustafa Karabulut, Hamide Avci, Eda Yalçınkaya, Merel Kimman, Wolfgang Viechtbauer, Alfarghal Mohamad, Vincent Van Rompaey, Nils Guinand, Angélica Perez Fornos, Levent Özlüoğlu, Osman Nuri Özgirgin, Raymond van de Berg

“…Data collection continued until thematic saturation was reached. …”
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New Epitopes for the Serodiagnosis of Human Borreliosis by Mônica E. T. Alcón-Chino, Virgínia L. N. Bonoldi, Rosa M. R. Pereira, Gilberto S. Gazeta, João P. R. S. Carvalho, Paloma Napoleão-Pêgo, Andressa M. Durans, André L. A. Souza, Salvatore G. De-Simone

“…Cross-reactivity was assessed through data bank access and in vitro analysis. Among the 19 epitopes identified, four were selected for further investigation based on their signal intensity, secondary structure, and peptide matching. …”
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Dalbavancin to facilitate early discharge in the treatment of complex musculoskeletal infections: a multi-centre real-life application by T. Azamgarhi, S. Warren, A. Scobie, N. Karunaharan, C. Perez-Sanchez, R. Houghton, S. Hassan, J. Lourtet-Hascoët, J. Lourtet-Hascoët, H. Kershaw, P. Sendi, K. Saeed, K. Saeed

“…Although dalbavancin is approved for acute bacterial skin and skin structure infections, its off-label use in complex musculoskeletal infection (MSKI) is increasing. …”
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Genome-wide identification of the regulatory network of mitogen-activated protein kinase signaling cascades gene families in Hevea Brasiliensis by Xiaojuan Huang, Manman Sun, Xiaoyu Du, Lin Quan, Jinquan Chao, Xiaomin Deng, Hongze Liao

“…Conserved motifs, gene structure, and motif analysis further bolster the validity of phylogenetic classification. …”
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Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis by Natalia E. Fares-Otero, Silvia Amoretti, Brisa Solé, Sarah L. Halligan, Eduard Vieta, Stefan Leucht, Soraya Seedat, Mathias Harrer

“…Study drop-out will be a secondary outcome that will serve as a measure of acceptability. Study selection and data extraction will be performed by at least two independent reviewers. …”
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Mapping, Modeling and Designing a Marble Quarry Using Integrated Electric Resistivity Tomography and Unmanned Aerial Vehicles: A Study of Adaptive Decision-Making by Zahid Hussain, Hanan ud Din Haider, Jiajie Li, Zhengxing Yu, Jianxin Fu, Siqi Zhang, Sitao Zhu, Wen Ni, Michael Hitch

“…UAV methodology involved data collection using a DJI Mavic 2 Pro (20 MP camera) with 4 K resolution images captured at 221 m altitude and 80 min flight duration. …”
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Ethical issues in implementation science: perspectives from a National Heart, Lung, and Blood Institute workshop by Neal W. Dickert, Donna Spiegelman, Jennifer S. Blumenthal-Barby, Garth Graham, Steven Joffe, Jeremy M. Kahn, Nancy E. Kass, Scott Y. H. Kim, Meeta P. Kerlin, Aisha T. Langford, James V. Lavery, Daniel D. Matlock, Kathleen N. Fenton, George A. Mensah

“…Similarly, even when research is exempt and informed consent unnecessary, Data Safety and Monitoring Board oversight of implementation studies may be advisable to ensure quality, address unexpected consequences, and identify overwhelming evidence of benefit. …”
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Enhancing nurses’ communication about psychosocial needs and changes in intimacy and sexuality in patients with advanced cancer: a mixed-method study by Susanne A.M. Arends, Corien M. Eeltink, Floortje K. Ploos van Amstel, Astrid W. Oosten, Donna C. Ruijter, Nelleke van der Loo, Barbara Harterink-Poker, Anneke L. Francke, Irene P. Jongerden

“…Methods: Between 2022 and 2023, we conducted a mixed methods study in six hospitals in The Netherlands. Data were collected three months before and three months after the training course. …”
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Usefulness of differential somatic cell count for udder health monitoring: Effect of intramammary infections, days in milk, quarter location, and parity on quarter-level differenti... by Mariana Fonseca, Daryna Kurban, Jean-Philippe Roy, Débora E. Santschi, Elouise Molgat, Simon Dufour

“…Given the hierarchical structure of the data, a 4-level, linear mixed model with herd, cow, and quarter as random intercepts was built with either SCS or DSCC as the outcome. …”
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Hydrothermal synthesis of a nickel-oxide-infused orange peel nanobiocomposite for enhanced heavy metal removal from mining wastewater by Jacques Romain Njimou, Velma Fai, Mary Tamwa Sieugaing, Djimongbaye Nguenamadje, John Godwin, Oben Bessem Genola, Guy Bertrand Noumi, Bankim Chandra Tripathy

“…Characterization techniques such as FTIR, XRD, SEM, and EDS reveal a highly porous morphology due to NiO nanoparticle integration within the OP matrix, a structure that provides numerous active sites for adsorption. …”
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Synthesis of the serotonin derivative 5-PT and establishment of a research system for protein serotonylation by XIAO Shuyu, TULAMATI Aziguli, YANG Yan, ZHANG Zhigang, YANG Xiaomei, DU Chang, ZHANG Xueli

“…Mass spectrometry analysis data showed that a significant amount of serotonylated proteins were enriched in various cells treated with 5-PT. …”
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